BioM-JEPA: joint-embedding prediction of graph-connected gene blocks in single cells
BioM-JEPA:单细胞中基于图连接基因块的联合嵌入预测
机构 * Westlake University(西湖大学) ; Centre for Artificial Intelligence and Robotics (CAIR), Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences (HKISI-CAS)(中国科学院香港创新研究院人工智能与机器人中心) ; Institute of Automation, Chinese Academy of Sciences (CASIA)(中国科学院自动化研究所) ; University of Chinese Academy of Sciences (UCAS)(中国科学院大学)
AI总结 BioM-JEPA通过预测图连接基因块的聚合表示学习单细胞嵌入,在CellBench任务中实现最低扰动响应误差,微调与保留嵌入吞吐量优于scFoundation,为单细胞表示学习提供新预测单元。
Comments 34 pages, 6 figures, and 13 supplementary tables (Tables S1-S13); includes Supplementary Information with detailed training and evaluation protocols. Numerical source data for all figures are provided as ancillary files; training code and the BioM-JEPA checkpoint will be released via GitHub