DeepFilters: Scattering-Aware Pupil Engineering with Learned Digital Filter Reconstruction for Extended Depth of Field Microscopy
DeepFilters: 通过学习的数字滤波器重建实现散射感知的瞳孔工程用于扩展深度场显微镜
机构 * Boston University, Department of Electrical and Computer Engineering(波士顿大学电气与计算机工程系) ; Georgia Tech Research Institute, Electro-Optical Systems Lab(佐治亚理工研究学院电光学系统实验室) ; Boston University, Department of Biology(波士顿大学生物学系) ; Harvard Medical School, Brigham and Women’s Hospital, Department of Orthopedic Surgery(哈佛医学院布里特妇女医院骨科系) ; Boston University, Neurophotonics Center(波士顿大学神经光子学中心) ; Boston University, Department of Biomedical Engineering(波士顿大学生物医学工程系)
AI总结 本文提出DeepFilters框架,通过校准的可微前向模型联合优化参数化瞳孔滤波器和基于数字滤波器的重建网络,实现无需重新训练的广泛泛化,扩展PSF至400微米以上并在生物组织中实现120微米深度的信号恢复。
Comments 38 pages (18 main text, 20 supplement), 23 Figures (7 main text, 16 supplement)