Retrieval-Augmented Multimodal Learning for Enzyme-Substrate Interaction Prediction Under Low-Homology Shift
检索增强的多模态学习用于低同源性偏移下的酶-底物相互作用预测
机构 * School of Information Science and Engineering, East China University of Science and Technology(华东理工大学信息科学与工程学院) ; Institute of Natural Sciences and Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University(上海交通大学自然科学研究院和张江高等研究院) ; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University(上海交通大学生命科学技术学院)
专题命中 跨模态检索 :multimodal(title,abstract);cross-modal(abstract)
AI总结 提出RAMMESI框架,通过跨模态交互建模、自适应融合和检索增强,解决酶-底物相互作用预测中稀疏正监督和低同源性分布偏移问题,在低序列一致性场景下表现优异。
Comments 13 pages, 6 figures