医学 AI

Polarization-artifact reduction and accuracy improvement of Jones-matrix polarization-sensitive optical coherence tomography by multi-focus averaging

Lida Zhu, Shuichi Makita, Junya Tamaoki, Yiqiang Zhu, Yiheng Lim, Makoto Kobayashi, Yoshiaki Yasuno

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref Biomedical Optics Express 15, 256-276 (2024)

Learning to Generalize towards Unseen Domains via a Content-Aware Style Invariant Model for Disease Detection from Chest X-rays

Mohammad Zunaed, Md. Aynal Haque, Taufiq Hasan

专题命中 生物医学文本 ：分类 cs.CV、cs.LG、eess.IV；biomedical(comments)

Comments Accepted to IEEE Journal of Biomedical and Health Informatics

Current poisson's ratio values of finite element models are too low to consider soft tissues nearly-incompressible: illustration on the human heel region

Nolwenn Fougeron, Alessio Trebbi, Bethany Keenan, Yohan Payan, Gregory Chagnon

专题命中 生物医学文本 ：medical image(abstract)；biomedical(journal_ref)

Journal ref Computer Methods in Biomechanics and Biomedical Engineering, 2023, pp.1 - 10

A 21.3%-Efficiency Clipped-Sinusoid UWB Impulse Radio Transmitter with Simultaneous Inductive Powering and Data Receiving

Nima Soltani, Hamed M. Jafari, Karim Abdelhalim, Hossein Kassiri, Xilin Liu, Roman Genov

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref IEEE Transactions on Biomedical Circuits and Systems, 2022

Multiresolution Dual-Polynomial Decomposition Approach for Optimized Characterization of Motor Intent in Myoelectric Control Systems

Oluwarotimi Williams Samuel, Mojisola Grace Asogbon, Rami Khushaba, Frank Kulwa, Guanglin Li

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref IEEE Transactions on Biomedical Engineering, November 2022

HeartSpot: Privatized and Explainable Data Compression for Cardiomegaly Detection

Elvin Johnson, Shreshta Mohan, Alex Gaudio, Asim Smailagic, Christos Faloutsos, Aurélio Campilho

专题命中 生物医学文本 ：分类 cs.CV、cs.LG、eess.IV；biomedical(comments)

Comments Accepted to IEEE-EMBS International Conference on Biomedical and Health Informatics 2022. IEEE copyrights may apply

Access to care: analysis of the geographical distribution of healthcare using Linked Open Data

Selene Baez Santamaria, Emmanouil Manousogiannis, Guusje Boomgaard, Linh P. Tran, Zoltan Szlavik, Robert-Jan Sips

专题命中 生物医学文本 ：biomedical(abstract,comments)

Comments Accepted at 4th Workshop on Semantic Web solutions for large-scale biomedical data analytics (SeWeBMeDA-2020)

Deep Learning for Regularization Prediction in Diffeomorphic Image Registration

Jian Wang, Miaomiao Zhang

专题命中 生物医学文本 ：分类 cs.CV、cs.LG、eess.IV；biomedical(journal_ref)

Comments 20 pages, 8 figures

Journal ref Machine Learning for Biomedical Imaging (MELBA) 2022

Simulation of corrosion and mechanical degradation of additively manufactured Mg scaffolds in simulated body fluid

Mohammad Marvi-Mashhadi, Wahaaj Ali, Muzi Li, Carlos González, Javier LLorca

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref Journal of the Mechanical Behavior of Biomedical Materials, 126, 104881, 2022

Automatic Estimation of Ulcerative Colitis Severity from Endoscopy Videos using Ordinal Multi-Instance Learning

Evan Schwab, Gabriela Oana Cula, Kristopher Standish, Stephen S. F. Yip, Aleksandar Stojmirovic, Louis Ghanem, Christel Chehoud

专题命中 生物医学文本 ：分类 cs.CV、cs.LG、eess.IV；biomedical(comments)

Comments *Co-Senior Authors. Accepted for publication in the Special Issue Journal of Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization and presented at the MICCAI 2021 AE-CAI $|$ CARE $|$ OR 2.0 Workshop

Strength, corrosion resistance and cellular response of interfaces in bioresorbable poly-lactic acid/Mg fiber composites for orthopedic applications

Wahaaj Ali, Mónica Echeverry-Rendón, Alexander Kopp, Carlos González, Javier LLorca

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref Journal of the Mechanical Behavior of Biomedical Materials, 123, 104781, 2021

Electrothermal equivalent three-dimensional Finite Element Model of a single neuron

Ilaria Cinelli, Michel Destrade, Maeve Duffy, Peter McHugh

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref IEEE Transactions on Biomedical Engineering, 65 (2018) 1373-1381

Learning deep representations for video-based intake gesture detection

Philipp V. Rouast, Marc T. P. Adam

专题命中 生物医学文本 ：分类 cs.CV、cs.LG、eess.IV；biomedical(comments)

Comments To be published in IEEE Journal of Biomedical and Health Informatics

A Learnable Despeckling Framework for Optical Coherence Tomography Images

Saba Adabi, Elaheh Rashedi, Hamed Mohebbi, Xue-wen Chen, Silvia Conforto, Mohammad. R. Nasiriavanaki

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Comments under review

Journal ref Journal of Biomedical Optics -2018

Improving Correlation with Human Judgments by Integrating Semantic Similarity with Second--Order Vectors

Bridget T. McInnes, Ted Pedersen

专题命中 生物医学文本 ：biomedical(abstract,comments)

Comments 10 pages, Appears in the Proceedings of the 16th Workshop on Biomedical Natural Language Processing (BioNLP-2017), August 2017, Vancouver, BC

Discovering Beaten Paths in Collaborative Ontology-Engineering Projects using Markov Chains

Simon Walk, Philipp Singer, Markus Strohmaier, Tania Tudorache, Mark A. Musen, Natalya F. Noy

专题命中 生物医学文本 ：biomedical(abstract,comments)

Comments Published in the Journal of Biomedical Informatics

NEMO: Extraction and normalization of organization names from PubMed affiliation strings

Siddhartha Jonnalagadda, Philip Topham

专题命中 生物医学文本 ：biomedical(abstract,journal_ref)

Journal ref Siddhartha Jonnalagadda, Philip Topham. NEMO: Extraction and normalization of organization names from PubMed affiliation strings. Journal of Biomedical Discovery and Collaboration, 2010 Oct 4;5:50-75

EIT Reconstruction Algorithms: Pitfalls, Challenges and Recent Developments

William R. B. Lionheart

专题命中 生物医学文本 ：biomedical(abstract,comments)

Comments A review paper for the 4th Workshop on Biomedical Applications of EIT, Manchester, UK, 2003

Journal ref Physiol. Meas. 25 (February 2004) 125-142

Phil Bourne (1953-2026): From Small Molecules to Big Data --- The Journey of a Multifaceted Visionary

菲尔·伯恩（1953-2026）：从小分子到大数据 —— 一位多面有远见者的历程

Andreas Prlić, Cameron Mura

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本文纪念2026年去世的菲尔·伯恩，回顾其从小分子到大数据的跨尺度科学生涯，提及他获国际计算生物学学会2026年度杰出服务奖却未能领奖，以及他在多领域的奠基贡献与纪念网站的相关信息。

Comments 8 pages, 3 figures

EpiBench: Can LLMs Understand Epitopes for Antibody Drug Discovery?

EpiBench：大型语言模型能否为抗体药物发现表位？

Zirui Wang, Jiaqi Wang, Qinghan Wang, Yuzhi Xu, Gang Du, Tingjun Hou, Odin Zhang

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本研究提出用于评估大型语言模型表位推理能力的基准EpiBench，发现现有通用LLMs在抗体药物发现相关表位推理上仍存局限，为改进序列感知型生物医学LLMs提供了测试平台。

AutoProteinEngine: A Large Language Model Driven Agent Framework for Multimodal AutoML in Protein Engineering

AutoProteinEngine：一种用于蛋白质工程多模态自动机器学习的大语言模型驱动智能体框架

Yungeng Liu, Zan Chen, Yu Guang Wang, Yiqing Shen

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 研究针对生物学家缺乏计算知识难以应用深度学习开展蛋白质工程的问题，提出AutoProteinEngine框架，集成LLMs与AutoML，经两项任务验证其性能优于传统方法，降低了深度学习应用门槛。

Omics Data Discovery Agents: Agent-Supported Retrieval, Reanalysis, and Synthesis of Published Omics Data

组学数据发现代理

Alexandre Hutton, Jesse G. Meyer

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本文提出了一种基于代理的框架，通过自动化提取和处理组学数据，实现对生物医学文献的可执行查询和大规模数据重用。

Enhancing Phenotype Recognition in Clinical Notes Using Large Language Models: PhenoBCBERT and PhenoGPT

利用大型语言模型增强临床笔记中的表型识别：PhenoBCBERT和PhenoGPT

Jingye Yang, Cong Liu, Wendy Deng, Da Wu, Chunhua Weng, Yunyun Zhou, Kai Wang

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本研究提出PhenoBCBERT和PhenoGPT两种模型，利用大型语言模型提升临床笔记中表型术语的自动识别与提取，从而推动疾病相关生物学研究。

Threat Vectors and the State of the Art in Defense Methods for Security in Neurotechnology

神经技术安全防御方法中的威胁向量与现状

Bryce-Allen Bagley, Nathaniel Rose, Quintus Kilbourn, Matthew Canham

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本文针对脑机接口安全研发滞后问题，回顾神经安全技术现状，全面调查BCI系统安全威胁，给出可应用于弥补神经安全差距的现有方法建议，助力提升神经技术安全。

SciHorizon-GENE: Benchmarking LLM for Life Sciences Inference from Gene Knowledge to Functional Understanding

SciHorizon-GENE：从基因知识到功能理解的生命科学推理基准测试

Xiaohan Huang, Meng Xiao, Chuan Qin, Qingqing Long, Jinmiao Chen, Yuanchun Zhou, Hengshu Zhu

机构 * Computer Network Information Center, Chinese Academy of Sciences（中国科学院计算机网络信息中心） ； University of the Chinese Academy of Sciences（中国科学院大学） ； DUKE-NUS Medical School, National University of Singapore（新加坡国立大学杜克-新加坡医学学校） ； Singapore Immunology Network, Agency for Science, Technology and Research（新加坡免疫网络，科技研究局） 纠错

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 针对大语言模型在基因级推理能力上的不足，构建了包含超过19万个人类基因和54万问题的基准SciHorizon-GENE，从研究关注敏感性、幻觉倾向、答案完整性和文献影响力四个生物学关键维度评估模型，揭示了模型在生成忠实、完整且基于文献的功能解释方面的持续挑战。

Comments Accepted by SIGKDD 2026. 12 pages

PRAXIS: Case-distilled and code-verified AI agents for biological research

PRAXIS：用于生物学研究的案例提炼与代码验证的AI智能体

Zhenyu Ma, Yuyang Song, Chunyi Yang, Jingyi Zhu, Limei Xu, Min Xiao, Xukai Jiang

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 提出PRAXIS框架，通过文献学习和案例提炼将研究经验转化为结构化长期记忆，支持生物计算任务中的问题定义、对象验证、方法选择等，实验表明基于案例的学习提升了复杂生物研究任务的方法选择、错误抑制和工作流组织。

Dynamic Density Estimation in Heterogeneous Cell Populations

异质细胞群体中的动态密度估计

Armin Küper, Robert Dürr, Steffen Waldherr

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本文提出了一种基于样本近似的密度估计方法，用于重建不可测的细胞属性，相比传统网格离散化方法，在准确性和计算效率上表现更优。

Comments 7 pages, 5 figures, this article has been accepted for publication in a future issue of IEEE Control Systems Letters

Numerical methods for interface coupling of compressible and almost incompressible media

可压缩与近不可压缩介质界面耦合的数值方法

Mauricio J. Del Razo, Randall J. LeVeque

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 研究开发了模拟冲击波从气体进入薄弹性固体和近不可压缩流体的数值方法，通过高分辨率冲击捕捉方法和自适应网格细化技术，简化了薄界面模型并提高了计算效率。

Journal ref SIAM Journal on Scientific Computing, 39.3: B486-B507 (2017)

Systemic physiological cliff at menopause revealed by temporal deconvolution of 300 million lab tests: a multi-cohort retrospective study

通过3亿次实验室检测的时间反卷积揭示更年期系统性生理悬崖：一项多队列回顾性研究

Glen Pridham, Yoav Hayut, Noa Lavi-Shoseyov, Michal Neeman, Noa Hovav, Yoel Toledano, Uri Alon

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 本研究提出一种从天文学借鉴的反卷积框架，利用大规模横截面数据重建女性更年期前后的系统性生理轨迹，发现更年期在多个生理系统（内分泌、骨骼、肝脏、肾脏、炎症和脂质）中引发阶梯式生理悬崖，且激素替代疗法可显著减弱这些突变。

Comments main text: pages 1-23, 5 figures, 1 table. supplemental: pages 24-51 8 figures, 5 tables, supplemental discussion

Sparse Contextual Coupling Reshapes Diffusion Geometry in Multilayer Hypergraphs

稀疏上下文耦合重塑多层超图中的扩散几何

Hao Ding, Sanjukta Krishnagopal

专题命中 生物医学文本 ：biomedical(abstract)；分类 q-bio

AI总结 该研究提出了一种基于扩散的框架，用于分析稀疏条件特定层如何重塑多层超图中的扩散几何，通过将密集的MSigDB功能基因集层与稀疏的疾病特定DGIdb药物-基因超图耦合，发现稀疏层对扩散距离和社区结构有显著影响。