A specialized reasoning large language model for accelerating rare disease diagnosis: a randomized AI physician assistance trial
一种用于加速罕见病诊断的专用推理大语言模型:随机AI辅助医生试验
机构 * Tsinghua Medicine, Tsinghua University(清华大学医学部,清华大学) ; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College(北京大学人民医院眼科,中国医学科学院 & 北京大学医学部) ; Department of Statistics and Data Science, Tsinghua University(清华大学统计与数据科学系) ; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College(北京大学人民医院风湿免疫科,中国医学科学院 & 北京大学医学部) ; Department of Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College(北京大学人民医院罕见病科,中国医学科学院 & 北京大学医学部) ; Department of Dermatology, Xijing Hospital, Air Force Medical University(西安空军军医大学西京医院皮肤科) ; School of Computer Science and Technology, East China Normal University (ECNU)(东华大学计算机科学与技术学院) ; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University(首都医科大学宣武医院神经外科) ; Department of Ophthalmology, National University of Singapore(新加坡国立大学眼科) ; Singapore Eye Research Institute, Singapore National Eye Centre(新加坡眼科学研究所,新加坡国家眼科中心) ; Ophthalmology and Visual Science Academic Clinical Program, Duke-NUS Medical School(杜克-国立新加坡大学医学学校眼科与视觉科学学术临床项目) ; Department of Pediatrics, The First Hospital of Tsinghua University(清华大学第一医院儿科) ; College of Future Technology, Peking University(北京大学未来技术学院) ; School of Health and Wellbeing, University of Glasgow(格拉斯哥大学健康与福祉学院)
专题命中 规划推理 :reasoning(title,abstract);分类 cs.CL、cs.AI
AI总结 提出开源推理大模型RaDaR(32B参数),通过增强推理训练和合成数据,在罕见病诊断中超越DeepSeek-R1等模型,随机试验显示其辅助使医生诊断准确率提升21.44个百分点。
Comments 36 pages, 5 figures