2510.17064
2026-06-04
cs.AI
BRAINCELL-AID: An Agentic AI Created Brain Cell Type Resource for Community Annotation
BRAINCELL-AID:用于社区注释的由AI代理创建的脑细胞类型资源
Rongbin Li, Wenbo Chen, Zhao Li, Rodrigo Munoz-Castaneda, Jinbo Li, Neha S. Maurya, Arnav Solanki, Huan He, Hanwen Xing, Meaghan Ramlakhan, Zachary Wise, Nelson Johansen, Zhuhao Wu, Hua Xu, Michael Hawrylycz, W. Jim Zheng
发表机构
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McWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston(德克萨斯大学健康科学中心休斯顿分校麦克威廉斯生物医学信息学学院)
;
Appel Alzheimer’s Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine(艾伯神经变性病研究机构、费尔家庭脑与心灵研究机构、韦尔·科恩医学中心)
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Department of Biomedical Informatics and Data Science, School of Medicine, Yale University(耶鲁大学医学院生物医学信息学与数据科学系)
;
Allen Institute for Brain Science(艾伦脑科学研究所)
AI总结
提出一种多智能体AI系统BRAINCELL-AID,结合检索增强生成和自由文本描述与本体标签,实现对单细胞RNA测序数据中基因集注释的准确性和鲁棒性提升,并应用于小鼠脑细胞图谱的注释。