Forecasting urban phenomena such as housing prices and public health indicators requires the effective integration of various geospatial data. Current methods primarily utilize task-specific models, while recent generic models for spatial representations often support only limited modalities and lack multimodal fusion capabilities. To overcome these challenges, we present UrbanFusion, a spatial representation model that features Stochastic Multimodal Fusion (SMF). The framework employs modality-specific encoders to process different types of inputs, including street view imagery, remote sensing data, cartographic maps, and points of interest (POIs) data. These multimodal inputs are integrated via a Transformer-based fusion module that learns unified representations. An extensive evaluation across 41 tasks in 56 cities worldwide demonstrates UrbanFusion's strong generalization and predictive performance compared to state-of-the-art GeoAI models. Specifically, it 1) outperforms prior models on location-encoding, 2) allows multimodal input during inference, and 3) generalizes well to regions unseen during training. UrbanFusion can flexibly utilize any subset of available modalities for a given location during both pretraining and inference, enabling broad applicability across diverse data availability scenarios.

Active feature acquisition (AFA) is a sequential decision-making problem where the goal is to improve model performance for test instances by adaptively selecting which features to acquire. In practice, AFA methods often learn from retrospective data with systematic missingness in the features and limited task-specific labels. Most prior work addresses acquisition for a single predetermined task, limiting scalability. To address this limitation, we formalize the meta-AFA problem, where the goal is to learn acquisition policies across various tasks. We introduce Learning-to-Measure (L2M), which consists of i) reliable uncertainty quantification over unseen tasks, and ii) an uncertainty-guided greedy feature acquisition agent that maximizes conditional mutual information. We demonstrate a sequence-modeling or autoregressive pre-training approach that underpins reliable uncertainty quantification for tasks with arbitrary missingness. L2M operates directly on datasets with retrospective missingness and performs the meta-AFA task in-context, eliminating per-task retraining. Across synthetic and real-world tabular benchmarks, L2M matches or surpasses task-specific baselines, particularly under scarce labels and high missingness.

In performative learning, the data distribution reacts to the deployed model - for example, because strategic users adapt their features to game it - which creates a more complex dynamic than in classical supervised learning. One should thus not only optimize the model for the current data but also take into account that the model might steer the distribution in a new direction, without knowing the exact nature of the potential shift. We explore how regularization can help cope with performative effects by studying its impact in high-dimensional ridge regression. We show that, while performative effects worsen the test risk in the population setting, they can be beneficial in the over-parameterized regime where the number of features exceeds the number of samples. We show that the optimal regularization scales with the overall strength of the performative effect, making it possible to set the regularization in anticipation of this effect. We illustrate this finding through empirical evaluations of the optimal regularization parameter on both synthetic and real-world datasets.

Current benchmarks are inadequate for evaluating progress in reinforcement learning (RL) for large language models (LLMs).Despite recent benchmark gains reported for RL, we find that training on these benchmarks' training sets achieves nearly the same performance as training directly on the test sets, suggesting that the benchmarks cannot reliably separate further progress.To study this phenomenon, we introduce a diagnostic suite and the Oracle Performance Gap (OPG) metric that quantifies the performance difference between training on the train split versus the test split of a benchmark. We further analyze this phenomenon with stress tests and find that, despite strong benchmark scores, existing RL methods struggle to generalize across distribution shifts, varying levels of difficulty, and counterfactual scenarios: shortcomings that current benchmarks fail to reveal.We conclude that current benchmarks are insufficient for evaluating generalization and propose three core principles for designing more faithful benchmarks: sufficient difficulty, balanced evaluation, and distributional robustness.

Vision-language models (VLMs) could power real-time assistants and autonomous agents, but they face a critical challenge: understanding near-infinite video streams without escalating latency and memory usage. Processing entire videos with full attention leads to quadratic computational costs and poor performance on long videos. Meanwhile, simple sliding window methods are also flawed, as they either break coherence or suffer from high latency due to redundant recomputation. In this paper, we introduce StreamingVLM, a model designed for real-time, stable understanding of infinite visual input. Our approach is a unified framework that aligns training with streaming inference. During inference, we maintain a compact KV cache by reusing states of attention sinks, a short window of recent vision tokens, and a long window of recent text tokens. This streaming ability is instilled via a simple supervised fine-tuning (SFT) strategy that applies full attention on short, overlapped video chunks, which effectively mimics the inference-time attention pattern without training on prohibitively long contexts. For evaluation, we build Inf-Streams-Eval, a new benchmark with videos averaging over two hours that requires dense, per-second alignment between frames and text. On Inf-Streams-Eval, StreamingVLM achieves a 66.18% win rate against GPT-4O mini and maintains stable, real-time performance at up to 8 FPS on a single NVIDIA H100. Notably, our SFT strategy also enhances general VQA abilities without any VQA-specific fine-tuning, improving performance on LongVideoBench by +4.30 and OVOBench Realtime by +5.96. Code is available at https://github.com/mit-han-lab/streaming-vlm.

Large language models (LLMs) augmented with knowledge graphs (KGs) offer a promising approach for knowledge-intensive reasoning. Central to this approach is the selection of appropriate reasoning paths in the KG. Yet, existing methods face a common limitation: reasoning path selection is often performed by separate modules using criteria that are only weakly connected to the reasoning requirements. This often results in selecting incorrect relations or premature pruning of relevant paths. We propose Search-on-Graph (SoG), a method that strengthens the connection between path selection and reasoning by having the LLM itself select which relations to follow, informed by both the available KG structure and the complete reasoning history. SoG follows an \textit{observe-think-navigate} paradigm: at each step, the LLM observes the relational connections available at the current entity, reasons about which path best advances toward answering the question, and navigates accordingly. This context-aware navigation fully exploits the LLM's reasoning capabilities rather than relying on independent selection modules with surrogate criteria. Experiments on six knowledge graph question answering (KGQA) benchmarks demonstrate that SoG outperforms state-of-the-art methods while requiring no task-specific fine-tuning and generalizing across different KG schemas.

Understanding the internal representations of large language models (LLMs) remains a central challenge for interpretability research. Sparse autoencoders (SAEs) offer a promising solution by decomposing activations into interpretable features, but existing approaches rely on fixed sparsity constraints that fail to account for input complexity. We propose AdaptiveK SAE (Adaptive Top K Sparse Autoencoders), a novel framework that dynamically adjusts sparsity levels based on the semantic complexity of each input. Leveraging linear probes, we demonstrate that context complexity is linearly encoded in LLM representations, and we use this signal to guide feature allocation during training. Experiments across ten language models demonstrate that this complexity-driven adaptation outperforms fixed-sparsity approaches on reconstruction fidelity, explained variance, cosine similarity and interpretability metrics while eliminating the burden of extensive hyperparameter tuning. Our code is available at: https://github.com/hiyukie/adaptiveK.

Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering. However, ensuring these models meet critical industry standards for factual accuracy, usefulness, and safety remains a challenge, especially for open-source solutions. We present a rigorous benchmarking framework using a dataset of over 1,000 health questions. We assess model performance across honesty, helpfulness, and harmlessness. Our results highlight trade-offs between factual reliability and safety among evaluated models -- Mistral-7B, BioMistral-7B-DARE, and AlpaCare-13B. AlpaCare-13B achieves the highest accuracy (91.7%) and harmlessness (0.92), while domain-specific tuning in BioMistral-7B-DARE boosts safety (0.90) despite its smaller scale. Few-shot prompting improves accuracy from 78% to 85%, and all models show reduced helpfulness on complex queries, highlighting ongoing challenges in clinical QA.

Direct Preference Optimization (DPO) has emerged as a simple and effective method for aligning large language models. However, its reliance on a fixed temperature parameter leads to suboptimal training on diverse preference data, causing overfitting on easy examples and under-learning from informative ones. Recent methods have emerged to counter this. While IPO addresses general overfitting, its uniform regularization can be overly conservative. The more targeted approach of $β$-DPO suffers from its own limitations: its batch-level adaptation applies a single, compromised temperature to mixed-margin pairs, its linear update rule can produce unstable negative $β$ values, and its filtering mechanism discards potentially useful training signals. In this work, we introduce Margin-Adaptive Direct Preference Optimization (MADPO), a method that provides a stable, data-preserving, and instance-level solution. MADPO employs a practical two-step approach: it first trains a reward model to estimate preference margins and then uses these margins to apply a continuous, adaptive weight to the DPO loss for each individual training sample. This re-weighting scheme creates an effective target margin that is amplified for hard pairs and dampened for easy pairs, allowing for granular control over the learning signal. We provide a comprehensive theoretical analysis, proving that MADPO has a well-behaved optimization landscape and is robust to reward model estimation errors. We validate our theory with experiments on a summarization task using human preference data. MADPO consistently outperforms strong baselines across a comprehensive sweep of decoding temperatures.

Autonomous surgical systems must adapt to highly dynamic environments where tissue properties and visual cues evolve rapidly. Central to such adaptability is feedback: the ability to sense, interpret, and respond to changes during execution. While feedback mechanisms have been explored in surgical robotics, ranging from tool and tissue tracking to error detection, existing methods remain limited in handling the topological and perceptual challenges of tissue dissection. In this work, we propose a feedback-enabled framework for autonomous tissue dissection that explicitly reasons about topological changes from endoscopic images after each dissection action. This structured feedback guides subsequent actions, enabling the system to localize dissection progress and adapt policies online. To improve the reliability of such feedback, we introduce visibility metrics that quantify tissue exposure and formulate optimal controller designs that actively manipulate tissue to maximize visibility. Finally, we integrate these feedback mechanisms with both planning-based and learning-based dissection methods, and demonstrate experimentally that they significantly enhance autonomy, reduce errors, and improve robustness in complex surgical scenarios.

Low-discrepancy points are designed to efficiently fill the space in a uniform manner. This uniformity is highly advantageous in many problems in science and engineering, including in numerical integration, computer vision, machine perception, computer graphics, machine learning, and simulation. Whereas most previous low-discrepancy constructions rely on abstract algebra and number theory, Message-Passing Monte Carlo (MPMC) was recently introduced to exploit machine learning methods for generating point sets with lower discrepancy than previously possible. However, MPMC is limited to generating point sets and cannot be extended to low-discrepancy sequences (LDS), i.e., sequences of points in which every prefix has low discrepancy, a property essential for many applications. To address this limitation, we introduce Neural Low-Discrepancy Sequences (NeuroLDS), the first machine learning-based framework for generating finite LDS. Drawing inspiration from classical LDS, we train a neural network to map indices to points such that the resulting sequences exhibit minimal discrepancy across all prefixes. To this end, we deploy a two-stage learning process: supervised approximation of classical constructions followed by unsupervised fine-tuning to minimize prefix discrepancies. We demonstrate that NeuroLDS outperforms all previous LDS constructions by a significant margin with respect to discrepancy measures. Moreover, we demonstrate the effectiveness of NeuroLDS across diverse applications, including numerical integration, robot motion planning, and scientific machine learning. These results highlight the promise and broad significance of Neural Low-Discrepancy Sequences. Our code can be found at https://github.com/camail-official/neuro-lds.

Publishing a large language model (LLM) benchmark (especially its ground-truth answers) on the Internet risks contaminating future LLMs and enabling evaluation gaming: it may be unintentionally (or intentionally) used to train or select a model, or exploited to overfit and hack leaderboards when labels are accessible. A common mitigation is to keep the benchmark private and let participants submit their models or predictions to the organizers, but this still permits test-set overfitting through feedback loops. To overcome this issue, we propose CapBencher, a way to publish benchmarks without fully disclosing the ground-truth answers, while preserving open evaluation of LLMs. The main idea is to reduce the best possible accuracy, i.e., Bayes accuracy, by injecting randomness to the answers by preparing several logically correct answers, and only include one of them as the solution in the benchmark. Not only does this obscure the ground-truth answers, but it also offers a test for leakage or gaming: since even fully capable models should not surpass the Bayes accuracy, any model that does is a strong signal. We show theoretically and empirically that CapBencher accurately detects test-set overfitting across diverse benchmarks, models, training methodologies, and scenarios.

We study finite-horizon offline reinforcement learning (RL) with function approximation for both policy evaluation and policy optimization. Prior work established that statistically efficient learning is impossible for either of these problems when the only assumptions are that the data has good coverage (concentrability) and the state-action value function of every policy is linearly realizable ($q^π$-realizability) (Foster et al., 2021). Recently, Tkachuk et al. (2024) gave a statistically efficient learner for policy optimization, if in addition the data is assumed to be given as trajectories. In this work we present a statistically efficient learner for policy evaluation under the same assumptions. Further, we show that the sample complexity of the learner used by Tkachuk et al. (2024) for policy optimization can be improved by a tighter analysis.

Recent research on reasoning models explores the meta-awareness of language models, including their ability to determine optimal thinking duration, recognize knowledge boundaries, and structure concept-level thinking. While current large reasoning models depend solely on answer-based verification, we show that adding meta-awareness objectives leads to significant performance gains over models without such meta-knowledge. MAPR (Meta-Awareness via Predictive Reward) utilizes a self-generated task of predicting rollout statistics - specifically length, pass-rate, and concepts used - allowing for verification against the actual statistics. Furthermore, by leveraging this self-predictive capability, the model can regulate its reasoning behavior by i) filtering out trivial or unsolvable prompts, ii) reducing lengthy generations that tend to be incorrect, and iii) generating hints relevant to the problem. The results are inspiring: MAPR yields significant improvements in both accuracy and training efficiency on various reasoning benchmarks. More specifically, our method can speed up GRPO training by over 1.28x to reach the same performance, and achieve 83.18% gain in accuracy on AIME25, and a 13.04% average gain over six mathematics benchmarks. The code is publicly available at https://github.com/akatigre/MAPR-RL.

For the combinatorial graph alignment problem (GAP) -- finding the node correspondence that maximizes the number of common edges (nce) between two unlabeled graphs -- properly initialized FAQ remains a strong classical baseline, while existing GNN approaches struggle in the purely structural setting. We introduce a chaining procedure: a sequence of Folklore-type (2-FWL) GNNs in which each network is trained with cross-entropy after decoding the previous network's similarity matrix and ranking nodes by their current alignment quality. This non-differentiable ranking step injects discrete combinatorial feedback at every link; at inference, we iterate the final network and keep the candidate with highest observed nce. On sparse Erdos-Renyi graphs at noise level 0.25, chained FGNNs with FAQ post-processing reach 85% accuracy versus 13% for FAQ initialized from the convex relaxation, and essentially 0% for prior GNN methods. On correlated regular graphs, where MPNNs with constant features produce identical node embeddings (1-WL fails to refine) and FAQ's convex initialization is degenerate, chaining is the only method we know that recovers a non-trivial alignment. On three real-world benchmarks (yeast PPI, coauthorship, and road networks), we show that recent comparisons underestimate FAQ by initializing it from a uniform doubly stochastic matrix; once FAQ is initialized from the convex relaxation it already surpasses prior reported numbers, and dataset-specific chained FGNNs further improve on this strengthened baseline.

Large Multimodal Models (LMMs) demonstrate impressive in-context learning abilities from few multimodal demonstrations, yet the internal mechanisms supporting such task learning remain opaque. Building on prior work of Large Language Models, we show that a small subset of attention heads in Large Multimodal Models is responsible for transmitting representations of visual relations. The activations of these attention heads, termed function vectors, can be extracted and manipulated to alter an LMM's performance on relational tasks. First, using synthetic and real image datasets, we apply causal mediation analysis to identify attention heads that strongly influence relational predictions, and extract multimodal function vectors that improve zero-shot accuracy at inference time. We further demonstrate that these multimodal function vectors can be fine-tuned with a modest amount of training data, while keeping LMM parameters frozen, to significantly outperform in-context learning baselines. Finally, we show that relation-specific function vectors can be linearly combined to solve analogy problems involving novel and untrained visual relations, highlighting the strong generalization ability of this approach. Through experiments on two LMMs, including OpenFlamingo and Qwen3-VL, our results show that these models encode visual relational knowledge within localized internal structures, which can be systematically extracted and optimized, thereby advancing our understanding of model modularity and enhancing control over relational reasoning in LMMs.

Individual Head-Related Transfer Functions (HRTFs) are starting to be introduced in many commercial immersive audio applications and are crucial for realistic spatial audio rendering. However, one of the main hesitations regarding their introduction is that creating individual HRTFs is impractical at scale due to the complexities of the HRTF measurement process. To mitigate this drawback, HRTF spatial upsampling has been proposed with the aim of reducing the measurements required. While prior work has seen success with different machine learning (ML) approaches, these models often struggle with long-range preservation of local spatial variation patterns across neighbouring source directions and generalization at high upsampling factors. In this paper, we propose a novel transformer-based architecture for HRTF upsampling, leveraging the attention mechanism to better capture spatial correlations across the HRTF sphere. Working in the spherical harmonic (SH) domain, our model learns to reconstruct high-resolution HRTFs from sparse input measurements with significantly improved accuracy. To enhance spatial coherence, we introduce a neighbour dissimilarity loss that promotes magnitude smoothness, yielding more realistic upsampling. We evaluate our method using both perceptual localization models and objective spectral distortion metrics. Experiments show that our model outperforms existing methods across several evaluation metrics in generating realistic, high-fidelity HRTFs.

Inverse materials design is shifting materials discovery from forward prediction to targeted proposal of candidates that satisfy objectives under physical constraints. Here, we review recent advances in generative crystal structure modeling, multimodal learning, and closed-loop design pipelines for crystalline solids. We survey how modern generators learn chemical-structural priors from large databases to enable controllable sampling of periodic structures, and compare leading model classes including variational autoencoders, normalizing flows, autoregressive formulations, and diffusion models. Particular attention is given to how feasibility constraints and physical priors are enforced across the workflow, through representation choices, training objectives, sampling-time guidance, and post-generation screening and relaxation. We also discuss how multimodal learning fuses diverse materials modalities, including crystal structures, thermodynamic, electronic information, microscopy, spectroscopy, processing context, and scientific text, to construct a more universal, transferable representation of chemical space. In addition, diverse inverse-design strategies are examined, particularly those that integrate conditional generation with latent optimization, Bayesian optimization, reinforcement learning, and active learning. Finally, we highlight recurring failure modes, such as surrogate exploitation, diversity collapse, distribution shift, and the stability-synthesizability gap, and outline discovery-grade evaluation practices based on staged reporting of validity, novelty, uniqueness, stability, and cost.

Agentic systems entering production typically operate as partially integrated assemblies where structural defects, not task-level errors, dominate the failure landscape. At this maturity level, task-level error detection may be infeasible: structural failure modes mask the signal that task-level monitors are designed to detect.We present a monitoring and triage methodology that decomposes agentic system evaluation into three dimensions (quality, suitability, efficiency) at three monitoring scopes (within-run, cross-run, structural), using variance as a characterization signal. Findings are routed through severity classification adapted from FMEA, concentrating human attention on the subset that warrants investigation. We evaluate on a synthetic testbed of 220 runs across 120 document bundles with controlled error injection.Three results emerge. Monitor scope determines failure type: within-run monitors surface deterministic stage defects (CV = 0.02), cross-run monitors surface stochastic integration consequences (CV = 1.25, 24% at L2), and a structural monitor identifies an integration gap with perfect consistency (CV = 0.00). Injected task-level errors are indistinguishable from clean baselines, confirming structural defects mask task-level signal. Deterministic triage routes 97% of findings to automated tracking, leaving the 2% reflecting variable behavior for human investigation.We propose, on Stage 1 evidence, a maturity-staging model in which monitoring transitions from structural characterization to error detection to reliability tracking as integration defects resolve. The taxonomy, CV-based scope characterization, and severity model transfer architecturally to document-driven, multi-stage agentic workflows in regulated industries; specific calibrations are domain-specific. Deploy monitoring early: the first thing it finds is the most important thing to fix.

Tool-augmented language agents speculatively issue likely future tool calls to hide latency, but those calls leak inferred user intent to external services before the agent commits to the branch. Every external observer that received the call retains the disclosure after the agent abandons the branch. Timing is the issue, not authorization: no commit-time cleanup, read-only restriction, or access-control allow-list unsends what an observer already holds. We call these invocations ghost tool calls and propose Speculative Tool Privacy Contracts, a runtime abstraction that treats observation before commitment as a first-class effect, distinct from state mutation. We implement the contracts in a prototype runtime and evaluate twelve policies across three corpora. Speculative dispatch increases what an observer can infer about user intent; post-hoc filters, read-only restrictions, and access-control allow-lists leave that inference intact; only issue-time policies that change or suppress the speculative call's argument or destination projection before dispatch reduce it.

Publicly available phonocardiogram (PCG) datasets remain limited in size and pathological diversity, constraining both auscultation training and the generalisation of automated heart-sound classifiers. A class-conditional diffusion model for PCG generation is developed in the log-mel domain and synthetic fidelity is assessed using complementary (i) physiology-inspired plausibility metrics, (ii) downstream label-consistency evaluation, and (iii) expert listening. Experiments use the Phy-sioNet/Computing in Cardiology Challenge 2016 dataset (3240 recordings) with recording-level splits. After preprocessing and quality control, 16,749 non-overlapping 4 s clips are mapped to a normalised 1 x 128 x 128 log-mel representation to train a conditional 2D U-Net denoiser with classifier-free guidance. Signal-level plausibility is quantified on reconstructed waveforms using three lightweight metrics: an envelope-autocorrelation rhythm score, an amplitude-based explosion score, and the dominant cycle lag. Synthetic clips preserve similar dominant cycle durations but exhibit reduced envelope periodicity and increased transient burstiness relative to real clips. For downstream evaluation, a ResNet-50 classifier achieves 92.24% accuracy on the held-out real test set and 82.8% accuracy on class-balanced synthetic batches, indicating that generated signals retain discriminative structure relevant to normal/abnormal classification. In a pilot expert listening study (60 clips, two clinicians), most synthetic clips are judged as heart-sound-like, while abnormality sensitivity is low for both real and synthetic 4 s excerpts. Overall, the results provide a practical baseline for diffusion-based PCG generation while highlighting remaining challenges in retaining abnormal acoustic cues and reducing reconstruction-induced artefacts.

The rapid development of LLMs has significantly advanced tabular question answering, but most systems cannot perform future-oriented numerical prediction. To address this gap, we introduce a novel task, Open-Domain Tabular Question Answering for Future Data Forecasting and Reasoning, and propose the first dataset to cover time-series forecasting and forecast-based reasoning scenarios using real estate data. This task poses challenges in retrieving precise historical data, overcoming the forecasting limitations of LLMs, and standardizing responses for diverse queries. To solve the above challenges, we propose TimeFore, an LLM agent-based framework that decomposes the problem into three collaborative roles: a Retriever autonomously generates SQL to fetch data, a Forecaster invokes external time-series models for higher accuracy, and an Analyzer synthesizes the results to construct a precise and consistent final answer. Extensive experiments demonstrate the effectiveness of our TimeFore.

Large language models (LLMs) are increasingly integrated into high-performance computing (HPC) workflows, accelerating scientific discovery through diverse perspectives such as code generation and domain-specific decision-making. Yet, how soft errors propagate and affect LLM inference remains largely unexplored. To bridge this gap, we present a comprehensive study on error propagation in LLM inference, enabled by our proposed LLMFI, a configurable and deterministic fault-injection framework. Using LLMFI, we systematically inject faults across three open-weighted LLMs and thirteen representative tasks, covering reasoning, multilingual, mathematical, and coding domains. In addition, we conduct fine-grained case studies that reveal critical vulnerability patterns. Overall, our study yields 17 takeaways that advance the understanding of error propagation in LLM inference and introduces four low-overhead directions to improve reliability through software-only modification, offering practical guidance for future error detection and mitigation.

Existing evaluations of neural operators and in-context operator learning rely primarily on prediction error, but accurate output prediction does not guarantee the correct local dynamical structure. A model may match solutions while exhibiting incorrect sensitivities, distorted frequency response, spurious mode coupling, or unstable tangent behavior. We introduce a Jacobian-based spectral audit for in-context operator learning. For a fixed prompt, we differentiate the network output with respect to the query function and view the resulting Jacobian as a learned tangent operator. Projecting it onto Fourier modes, we obtain a local spectral characterization of the inferred operator, including frequency-dependent gains, phase structure, and cross-mode coupling. The audit complements standard prediction metrics by testing whether the model reproduces local mechanisms of the underlying PDE operator rather than only outputs. Across benchmarks, the audit reveals distinct operator-level phenomena, including phase transport, viscosity-dependent damping, nonlinear mode coupling, and reaction--diffusion stability structure. It also detects failures partially hidden by prediction-error metrics, including high-frequency degradation, incorrect phase recovery, and prompt--operator inconsistencies. Corrupted or internally inconsistent prompts lead to degraded tangent-operator structure even when pointwise predictions remain partially accurate. Our results suggest that prediction accuracy and local operator fidelity are distinct properties of learned neural operators. Our framework also provides a diagnostic for stability, sensitivity, and operator consistency.

Quantum LDPC code discovery requires searching large algebraic design spaces while reliably certifying the parameters and equivalence classes of any candidates found. We introduce an LLM-guided evolutionary workflow in which language models mutate Python programs that generate bivariate-bicycle and perturbed bivariate-bicycle code ansätze. Across five campaigns, the system performed approximately 1{,}650 evolutionary iterations, screened about $2 \times 10^5$ candidate codes, and required ${\sim}140$ hours of computation and ${\sim}$US\$400 in LLM inference cost. Candidate codes are evaluated through a staged validation pipeline combining $\mathrm{GF}(2)$ rank computation, distance estimation and certification, mixed-integer linear programming, BLISS Tanner-graph deduplication, decomposability analysis, and local-Clifford equivalence checks. At block length $n \leq 360$, the workflow identifies 465 distinct candidate codes: 97 CSS bivariate-bicycle codes and 368 non-CSS perturbed variants. The CSS search recovers known high-performing codes and finds new finite-length representatives, including an indecomposable [[288,16,12]] code and higher-weight codes with up to $k = 50$ at distance $d = 8$. The non-CSS search produces perturbed codes matching the gross-code figure of merit at [[144,12,12]], along with additional high-distance candidates reported as certified values or upper bounds according to MILP status. Overall, these results show that LLM-guided program evolution can serve as a practical tool for structured quantum-code discovery when paired with independent evaluation.

Many machine learning problems, including similarity learning, ranking, and clustering, rely on empirical pairwise loss functions whose quadratic computational cost quickly becomes prohibitive at scale. We demonstrate how a frugal approach that retains only a fraction of the available information on pairs can achieve estimation or optimization performance comparable to that obtained by using all pairs, by leveraging survey sampling techniques. A central finding, supported by both theory and experiments, is that such sampling plans must target pairs directly rather than individual observations. In particular, for pairwise losses between high-dimensional vectors such as embeddings in vision or graph learning, assigning higher inclusion probabilities to informative pairs using suitable auxiliary information yields performance close to full pairwise evaluation, providing a principled and theoretically grounded trade-off between accuracy and computational cost.

Autonomous LLM agents increasingly operate in stateful environments where they access tools, files, memory, and external services. While such capabilities enable complex real-world workflows, they also introduce security risks that are difficult to capture with existing evaluations. Current agent security benchmarks often rely on manually curated tasks, provide limited coverage of emerging threats, and focus primarily on final outcomes rather than the execution processes that lead to unsafe behavior. We introduce SeClaw, a framework that combines specification-driven security task synthesis with execution-based security evaluation for Autonomous agents. Spec-driven security task synthesis enables scalable and controllable construction of security tasks from structured risk specifications, while SeClaw docker provides a standardized testbed for evaluating agent behavior under diverse safety-risk scenarios. The benchmark covers risks arising from resources, user tasks, environments, and intrinsic agent behaviors, and supports trajectory-aware assessment of unsafe actions beyond final responses. By bridging systematic task synthesis and reproducible security evaluation, SeClaw provides a practical foundation for measuring, diagnosing, and comparing security failures in autonomous LLM agents. The code is available at https://github.com/seclaw-eval/seclaw-eval.

Chronic pain diminishes quality of life by decreasing functional ability, yet objectively measuring this functional impact remains challenging in real-world settings. While optical motion capture provides high precision for assessing altered movement quality, it is costly and restricted to laboratory environments. We aimed to develop and validate Quantitative Movement Testing (QMT), a computer vision pipeline extracting 3D kinematic biomarkers from standard monocular smartphone video, balancing clinical accessibility with biomechanical accuracy. We validated the QMT pipeline, utilising deep learning-based 3D pose-estimation, against gold-standard optical motion capture in healthy controls (N=13). Following leave-one-subject-out calibration to correct systematic bias, we deployed QMT in two prospective clinical cohorts to assess real-world utility: a pre- and post-intervention trial for fibromyalgia patients, and a 30-day longitudinal at-home monitoring study of chronic sciatica patients and healthy controls. In laboratory validation, QMT extracted clinical kinematic metrics with high agreement to optical motion capture, yielding strong correlations (r > 0.85) and low mean absolute errors. QMT demonstrated high test-retest reliability (r > 0.86) in fibromyalgia patients and successfully tracked day-to-day movement fluctuations in chronic sciatica. While real-world home settings introduced higher measurement variance than lab settings, QMT found group-level differences between healthy controls and sciatica patients based entirely on remote recordings. Monocular 3D pose estimation offers a scalable alternative to traditional assessments. QMT provides an objective, accessible biomarker for tracking disease progression and treatment response in clinical trials, though further research is needed to optimise reliability in home environments.

State-space models are traditionally based on physical knowledge, but multi-step predictions from these physical models can be poor due to model inaccuracy. Black-box deep learning has shown promise as an alternative. However, these methods rely on the availability of large datasets and potentially available physical knowledge is neglected. We propose the PG-RSSNN, a physics-guided recurrent state-space neural network that incorporates recurrent structures to enable the use of non-saturating activation functions in multi-step prediction. It mitigates the vanishing gradients and eliminates the risk of numerical divergence in training seen in existing structures that feed back state estimates. Results across multiple systems with various physical model imperfections, from linear state-space models with Gaussian noise to a robotic arm and a cascaded water tank system, show that the proposed PG-RSSNN maintains stable training behavior, and improves multi-step predictions, as compared with black-box neural networks and physics-only models, even with limited training data and when physical models are only partially known.

Predicting whether an individual with Alzheimer's disease will experience mild or severe disease progression is essential for personalized treatment. Typically, practitioners seek to predict the distribution of a discrete disease score, conditional on an individual's current MRI volume and their historical disease trajectory. Classical statistical regression models and single-task neural networks are not well-suited for this purpose because fitting separate models is infeasible (since each individual typically has few observations), while ignoring individual-level correlation leads to poor generalization. Meta-learning, in contrast, provides a natural avenue to dynamically predict distributions without retraining and model nonlinear relationships between the outcome and covariates. Motivated by this, we propose a Bayesian meta-learner that is trained on multiple individuals but tailors the predictive disease score distribution to each individual's historical data. Our model predicts on unseen individuals without retraining, scales linearly with the number of historical observations, and is guaranteed to be less overconfident when predicting long-term disease scores compared to its deterministic counterpart. On real-world data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, our model achieves performance competitive with both single-task models and deterministic meta-learners, while substantially improving performance when predicting long-term disease progression.