Validation gating is a fundamental component of classical Kalman-based tracking systems. Only measurements whose normalized innovation squared (NIS) falls below a prescribed threshold are considered for state update. While this procedure is statistically motivated by the chi-square distribution, it implicitly replaces the unconditional innovation process with a conditionally observed one, restricted to the validation event. This paper shows that innovation statistics computed after gating converge to gate-conditioned rather than nominal quantities. Under classical linear--Gaussian assumptions, we derive exact expressions for the first- and second-order moments of the innovation conditioned on ellipsoidal gating, and show that gating induces a deterministic, dimension-dependent contraction of the innovation covariance. The analysis is extended to NN association, which is shown to act as an additional statistical selection operator. We prove that selecting the minimum-norm innovation among multiple in-gate measurements introduces an unavoidable energy contraction, implying that nominal innovation statistics cannot be preserved under nontrivial gating and association. Closed-form results in the two-dimensional case quantify the combined effects and illustrate their practical significance.

A growing body of empirical research suggests that generative AI narrows performance gaps between novice and expert workers on routine tasks--the so-called "equalizer" effect. This paper challenges the generality of that conclusion. Drawing on cognitive augmentation theory, expert-novice research, and structured observations of in-house generative-AI use across a small software product team, we argue that AI functions primarily as a cognitive amplifier: a system whose output quality depends fundamentally on the expertise of the human who directs it. We present a framework comprising three layers of human contribution (problem definition, quality evaluation, iterative refinement) and three levels of engagement (passive acceptance, iterative collaboration, cognitive direction), demonstrating that domain expertise--not prompt engineering skill--determines amplification effectiveness. We reconcile the equalizer and amplifier perspectives by proposing that AI equalizes performance on well-structured, routine tasks while amplifying pre-existing differences on complex tasks requiring deep judgment. This reconciliation carries direct implications for hybrid human-AI system design: rather than building AI that replaces expertise, we should build AI that rewards and develops it. We outline a research agenda for the HHAI community centered on expertise-sensitive AI design, adaptive collaboration interfaces, and longitudinal studies of human capability development in AI-augmented work.

Purpose: The Unadjusted Langevin Algorithm (ULA) in combination with diffusion models can generate high quality MRI reconstructions with uncertainty estimation from highly undersampled k-space data. However, sampling methods such as diffusion posterior sampling (DPS) or likelihood annealing suffer from long reconstruction times and the need for parameter tuning. The purpose of this work is to develop a robust sampling algorithm with fast convergence. Theory and Methods: In the reverse diffusion process used for sampling the posterior, the exact likelihood is multiplied with the diffused prior at all noise scales. To overcome the issue of slow convergence, preconditioning is used. The method is trained on fastMRI data and tested on retrospectively undersampled brain data of a healthy volunteer. Results: For posterior sampling in Cartesian and non-Cartesian accelerated MRI the new approach outperforms annealed sampling and DPS in terms of reconstruction speed and sample quality. Conclusion: The proposed exact likelihood with preconditioning enables rapid and reliable posterior sampling across various MRI reconstruction tasks without the need for parameter tuning.

Multi-period image collections are common in real-world applications. Cities are re-scanned for mapping, construction sites are revisited for progress tracking, and natural regions are monitored for environmental change. Such data form multi-period scenes, where geometry and appearance evolve. Reconstructing such scenes is an important yet underexplored problem. Existing pipelines rely on incompatible assumptions: static and in-the-wild methods enforce a single geometry, while dynamic ones assume smooth motion, both failing under long-term, discontinuous changes. To solve this problem, we introduce ChronoGS, a temporally modulated Gaussian representation that reconstructs all periods within a unified anchor scaffold. It's also designed to disentangle stable and evolving components, achieving temporally consistent reconstruction of multi-period scenes. To catalyze relevant research, we release ChronoScene dataset, a benchmark of real and synthetic multi-period scenes, capturing geometric and appearance variation. Experiments demonstrate that ChronoGS consistently outperforms baselines in reconstruction quality and temporal consistency. Our code and the ChronoScene dataset are publicly available at https://github.com/ZhongtaoWang/ChronoGS.

We introduce a density-power weighted variant for the Stein operator, called the $γ$-Stein operator. This is a novel class of operators derived from the $γ$-divergence, designed to build robust inference methods for unnormalized probability models. The operator's construction (weighting by the model density raised to a positive power $γ$ inherently down-weights the influence of outliers, providing a principled mechanism for robustness. Applying this operator yields a robust generalization of score matching that retains the crucial property of being independent of the model's normalizing constant. We extend this framework to develop two key applications: the $γ$-kernelized Stein discrepancy for robust goodness-of-fit testing, and $γ$-Stein variational gradient descent for robust Bayesian posterior approximation. Empirical results on contaminated Gaussian and quartic potential models show our methods significantly outperform standard baselines in both robustness and statistical efficiency.

Graphons, as limits of graph sequences, provide an operator-theoretic framework for analyzing the asymptotic behavior of graph neural operators. Spectral convergence of sampled graphs to graphons induces convergence of the corresponding neural operators, enabling transferability analyses of graph neural networks (GNNs). This paper develops a unified spectral framework that brings together convergence results under different assumptions on the underlying graphon, including no regularity, global Lipschitz continuity, and piecewise-Lipschitz continuity. The framework places these results in a common operator setting, enabling direct comparison of their assumptions, convergence rates, and tradeoffs. We further illustrate the empirical tightness of these rates on synthetic and real-world graphs.

Developers consistently use version constraints to specify acceptable versions of the dependencies for their project. Pinning dependencies can reduce the likelihood of breaking changes, but comes with a cost of manually managing the replacement of outdated and vulnerable dependencies. On the other hand, floating can be used to automatically get bug fixes and security fixes, but comes with the risk of breaking changes. Security practitioners advocate pinning dependencies to prevent against software supply chain attacks, e.g., malicious package updates. However, since pinning is the tightest version constraint, pinning is the most likely to result in outdated dependencies. Nevertheless, how the likelihood of becoming outdated or vulnerable dependencies changes across version constraint types is unknown. The goal of this study is to aid developers in making an informed dependency version constraint choice by empirically evaluating the likelihood of dependencies becoming outdated or vulnerable across version constraint types at scale. In this study, we first identify the trends in dependency version constraint usage and the patterns of version constraint type changes made by developers in the npm, PyPI, and Cargo ecosystems. We then modeled the dependency state transitions using survival analysis and estimated how the likelihood of becoming outdated or vulnerable changes when using pinning as opposed to the rest of the version constraint types. We observe that among outdated and vulnerable dependencies, the most commonly used version constraint type is floating-minor, with pinning being the next most common. We also find that floating-major is the least likely to result in outdated and floating-minor is the least likely to result in vulnerable dependencies.

Diffusion Posterior Sampling (DPS) provides a principled Bayesian approach to inverse problems by sampling from $p(x_0 \mid y)$. While posterior sampling is valuable for capturing uncertainty and multi-modality, many classical and practical inverse problem settings ultimately prioritize accurate point estimation -- most notably the MAP estimator, which has long served as a standard reconstruction objective in imaging and scientific applications. We introduce Local MAP Sampling (LMAPS), a new inference framework that iteratively solves local MAP subproblems along the diffusion trajectory. This perspective clarifies their connection to global MAP and DPS, offering a unified probabilistic interpretation for optimization-based methods. Building on this foundation, we develop practical algorithms with a covariance approximation motivated by a Gaussian prior assumption, and a reformulated objective for stability and interpretability. Across a broad set of image restoration and scientific tasks, LMAPS achieves state-of-the-art performance.

How can we generate samples from a conditional distribution that we never fully observe? This question arises across a broad range of applications in both modern machine learning and classical statistics, including image post-processing in computer vision, approximate posterior sampling in simulation-based inference, and conditional distribution modeling in complex data settings. In such settings, compared with unconditional sampling, additional feature information can be leveraged to enable more adaptive and efficient sampling. Building on this, we introduce Conditional Generator using MMD (CGMMD), a novel framework for conditional sampling. Unlike many contemporary approaches, our method frames the training objective as a simple, adversary-free direct minimization problem. A key feature of CGMMD is its ability to produce conditional samples in a single forward pass of the generator, enabling practical one-shot sampling with low test-time complexity. We establish rigorous theoretical bounds on the loss incurred when sampling from the CGMMD sampler, and prove convergence of the estimated distribution to the true conditional distribution. In the process, we also develop a uniform concentration result for nearest-neighbor based functionals, which may be of independent interest. Finally, we show that CGMMD performs competitively on synthetic tasks involving complex conditional densities, as well as on practical applications such as image denoising and image super-resolution.

The Universal Thermal Climate Index (UTCI) is a measure of thermal comfort that quantifies how humans experience environmental conditions. Due to its robustness and versatility as a bioclimatic indicator, it has been extensively employed across a wide range of studies in bioclimatology and is increasingly used as an operational measure of outdoor thermal comfort. Calculating the UTCI value from the relevant environmental parameters is nominally not straightforward, which is why using a 6th-degree polynomial approximation has become the standard way to calculate UTCI values. Although it is computationally efficient, the error of this polynomial approximation can be substantial. The goal of this study was to develop an improved version of the polynomial approximation - one that retains comparable computational efficiency but is more robust in terms of numerical stability and substantially more accurate, particularly in reducing the frequency of larger errors. This goal was achieved using sparse orthogonal regression, namely sparse regression with an orthogonal polynomial basis, which not only substantially reduces the average errors (i.e., the mean error, the mean absolute error, and the root mean square error) but also drastically reduces the frequency of large errors. By leveraging Legendre polynomial bases, approximation models could be constructed that efficiently populate a Pareto front of accuracy versus complexity and exhibit stable, hierarchical coefficient structures across varying model capacities. Training the new approximation models over only 20% of the data, with the testing performed over the remaining 80%, highlights successful generalization, with the results being robust under bootstrapping. The decomposition effectively approximates the UTCI as a Fourier-like expansion in an orthogonal basis, yielding results near the theoretical optimum in the L2 (least squares) sense.

Building on our previous work on Fredholm Neural Networks (Fredholm NNs/ FNNs) for solving integral equations, we extend the framework to inverse problems for linear and nonlinear elliptic partial differential equations. The proposed scheme consists of a custom-designed deep neural network (DNN) in which the number of layers, weights, biases and hyperparameters are computed in an explainable manner based on a fixed-point scheme, and we therefore refer to this as the Potential Fredholm Neural Network (PFNN). We first build the PFNN as a method for solving the forward problem, showing that this approach ensures both a high accuracy and explainability, achieving small errors in the interior of the domain, and near machine-precision on the boundary. We then use this approach to solve inverse problems for elliptic PDEs, and provide a rigorous proof for the consistency of the scheme and error bounds for both the interior and boundary of the domain, tied directly to the architecture of the PFNN. In particular, we show that these error bounds depend on the approximation of the boundary function and the integral discretization scheme, both of which directly correspond to components of the Fredholm NN architecture. In this way, we construct an explainable scheme that provides accurate solutions to the inverse problems, whilst still explicitly respecting the boundary conditions, due to the architecture of the PFNN. We assess the performance of the proposed scheme for linear and semi-linear elliptic PDEs in two and three dimensions.

Emerging economies, particularly the MINT countries (Mexico, Indonesia, Nigeria, and Türkiye), are gaining influence in global stock markets, although they remain susceptible to the economic conditions of developed countries like the G7 (Canada, France, Germany, Italy, Japan, the United Kingdom, and the United States). This interconnectedness and sensitivity of financial markets make understanding these relationships crucial for investors and policymakers to predict stock price movements accurately. To this end, we examined the main stock market indices of G7 and MINT countries from 2012 to 2024, using a recent graph neural network (GNN) algorithm called multivariate time series forecasting with graph neural network (MTGNN). This method allows for considering complex spatio-temporal connections in multivariate time series. In the implementations, MTGNN revealed that the US and Canada are the most influential G7 countries regarding stock indices in the forecasting process, and Indonesia and Türkiye are the most influential MINT countries. Additionally, our results showed that MTGNN outperformed traditional methods in forecasting the prices of stock market indices for MINT and G7 countries. Consequently, the study offers valuable insights into economic blocks' markets and presents a compelling empirical approach to analyzing global stock market dynamics using MTGNN.

Large Language Models (LLMs) have recently been leveraged for asset pricing tasks and stock trading applications, enabling AI agents to generate investment decisions from unstructured financial data. However, most evaluations of LLM timing-based investing strategies are conducted on narrow timeframes and limited stock universes, overstating effectiveness due to survivorship and data-snooping biases. We critically assess their generalizability and robustness by proposing FINSABER, a backtesting framework evaluating timing-based strategies across longer periods and a larger universe of symbols. Systematic backtests over two decades and 100+ symbols reveal that previously reported LLM advantages deteriorate significantly under broader cross-section and over a longer-term evaluation. Our market regime analysis further demonstrates that LLM strategies are overly conservative in bull markets, underperforming passive benchmarks, and overly aggressive in bear markets, incurring heavy losses. These findings highlight the need to develop LLM strategies that are able to prioritise trend detection and regime-aware risk controls over mere scaling of framework complexity.

Automation of sleep analysis, including both macrostructural (sleep stages) and microstructural (e.g., sleep spindles) elements, promises to enable large-scale sleep studies and to reduce variance due to inter-rater incongruencies. While individual steps, such as sleep staging and spindle detection, have been studied separately, the feasibility of automating multi-step sleep analysis remains unclear. In this case study, we evaluate whether a fully automated analysis using validated machine learning models for sleep staging (RobustSleepNet) and subsequent spindle detection (SUMOv2) can replicate findings from an expert-based study of bipolar disorder. The automated analysis qualitatively reproduced key findings from the expert-based study, including significant differences in fast spindle densities between bipolar patients and healthy controls, accomplishing in minutes what previously took months to complete manually. While the results of the automated analysis differed quantitatively from the expert-based study, possibly due to biases between expert raters or between raters and the models, the models individually performed at or above inter-rater agreement for both sleep staging and spindle detection. Our results demonstrate that fully automated approaches have the potential to facilitate large-scale sleep research. We are providing public access to the tools used in our automated analysis by sharing our code and introducing SomnoBot, a privacy-preserving sleep analysis platform.

Generative information retrieval (GenIR) is a promising neural retrieval paradigm that formulates document retrieval as a document identifier (docid) generation task, allowing for end-to-end optimization toward a unified global retrieval objective. However, existing GenIR models suffer from token-level misalignment, where models trained to predict the next token often fail to capture document-level relevance effectively. While reinforcement learning-based methods, such as reinforcement learning from relevance feedback (RLRF), aim to address this misalignment through reward modeling, they introduce significant complexity, requiring the optimization of an auxiliary reward function followed by reinforcement fine-tuning, which is computationally expensive and often unstable. To address these challenges, we propose direct document relevance optimization (DDRO), which aligns token-level docid generation with document-level relevance estimation through direct optimization via pairwise ranking, eliminating the need for explicit reward modeling and reinforcement learning. Experimental results on benchmark datasets, including MS MARCO document and Natural Questions, show that DDRO outperforms reinforcement learning-based methods, achieving a 7.4% improvement in MRR@10 for MS MARCO and a 19.9% improvement for Natural Questions. These findings highlight DDRO's potential to enhance retrieval effectiveness with a simplified optimization approach. By framing alignment as a direct optimization problem, DDRO simplifies the ranking optimization pipeline of GenIR models while offering a viable alternative to reinforcement learning-based methods.

Constructing fast and accurate surrogate models is a key ingredient for making robust predictions in many topics. We introduce a new model, the Multiparameter Eigenvalue Problem (MEP) emulator. The new method connects emulators and can make predictions directly from observables to observables. We present that the MEP emulator can be trained with data from Eigenvector Continuation (EC) and Parametric Matrix Model (PMM) emulators. A simple simulation on a one-dimensional lattice confirms the performance of the MEP emulator. Using $^{28}$O as an example, we also demonstrate that the predictive probability distribution of the target observables can be easily obtained through the new emulator.

The computation of the dominant eigenpair for symmetric positive semidefinite matrices is fundamental in numerical optimization. This work shifts the paradigm from the classical Rayleigh quotient to an unconstrained difference formulation, whose global optimum recovers the dominant eigenpair. Within this framework, we prove that gradient descent with a constant step-size $α\in (0, 1)$ converges almost surely to the global optimum at a local linear rate. This analysis thereby reinterprets the classical power method as the conservative special case $α=1/2$ and rigorously establishes its asymptotic sub-optimality. To advance this first-order scheme, we propose the Split-Merge algorithm based on the majorization-minimization principle. After splitting the matrix, we introduce auxiliary vectors to effectively merge the decomposition factors, resulting in a matrix-free and parameter-free iteration that captures tighter curvature information. We establish that Split-Merge converges almost surely to a global minimizer, and show that the iteration exhibits a spectral peeling mechanism that suppresses the targeted eigenspace, potentially surpassing the static linear rate of power iterations. Numerical evaluations across synthetic and real-world datasets confirm that our method has scalable efficiency, achieving speed-ups exceeding $10\times$ over the power method, with performance comparable to subspace iterations.

Visual content on social media has become increasingly influential in shaping political discourse and civic engagement, but it also limits participation due to the increased cost of multimedia production. In tandem, the growth of generative AI provides novel ways for citizens to participate in politics by lowering these costs. Drawing on a dataset of 239,526 Instagram images, we analyze the effects of synthetic images during the 2024 United States presidential election, using a multimodal workflow combining computer vision, large language models, and facial affect analysis. Results show that meme format is a stronger predictor of engagement than AI-generated content alone. However, AI-generated memes yield a significant interaction effect, suggesting synergistic increases in engagement when synthetic imagery is integrated with memes through human curation. We also characterize how users curate images. Partisans use AI in different ways: Democrat-leaning users tend to use it for in-group support, whereas Republican-leaning users more often employ it for out-group attacks. Users generally select happier synthetic faces compared to real photographs. We define generative memesis as a mode of communication in which memes are no longer shared person-to-person, but mediated by AI through customized visuals. We discuss how generative AI may empower civic participation, the bifurcation of content production and curation, and its implications for in the history of novel technologies and participatory culture.

Cells in multicellular organisms coordinate to form structural and functional niches. With spatial transcriptomics (ST) enabling gene expression profiling in spatial contexts, it has been revealed that spatial niches serve as cohesive and recurrent units in physiological and pathological processes. These observations suggest universal tissue organization principles encoded by conserved niche patterns, and call for a query-based niche analytical paradigm beyond current computational tools. In this work, we defined the niche-query task, which is to identify similar niches across ST samples given a niche of interest (NOI). We further developed QueST, a specialized method for solving this task. QueST models each niche as a subgraph, uses contrastive learning to learn discriminative niche embeddings, and incorporates adversarial training to mitigate batch effects. In simulations and benchmark datasets, QueST outperformed existing methods repurposed for niche querying, accurately capturing niche structures in heterogeneous environments and demonstrating strong generalizability across diverse sequencing platforms. Applied to tertiary lymphoid structures in renal and lung cancers, QueST revealed functionally distinct niches associated with patient prognosis and uncovered conserved and divergent spatial architectures across cancer types. Applied to a combinatorial spatial perturbation dataset, QueST demonstrated a complete de novo discovery-oriented workflow, characterizing previously unresolved tumor nodules through querying. These results demonstrate that QueST enables systematic, quantitative profiling of spatial niches across samples, providing a powerful tool to dissect spatial tissue architecture in health and disease.

Large Language Models (LLMs) are reshaping knowledge work, yet their impact on voluntary, self-guided open innovation forums (contributors choose tasks without managerial direction) may differ fundamentally from effects observed in organizational settings. We study this question in open-source software development, where individuals' contributions collectively drive innovation at a community level. Unlike product innovation, where typologies for classifying innovation are well established, knowledge work in open-source settings calls for a distinction grounded in the cognitive demand a task places on the contributor. Burgeoning literature distinguishes substantive contributions, which require creative problem formulation to introduce new functionality, from incremental contributions, which draw on comprehension of existing code to maintain and refine it. We exploit a natural experiment around GitHub Copilot's launch in October 2021, where Copilot supported languages like Python while not supporting R for business reasons, creating an exogenous partition between otherwise comparable ecosystems. Using three complementary identification strategies and two classification approaches, we find that Copilot availability increases open-source contributions by 28 to 40 percent. The increase in incremental contributions is significantly larger than the increase in substantive contributions across all specifications. This disparity is more pronounced in projects with higher activity levels and widens following a model upgrade: LLMs function more effectively when existing context helps define the problem and constrain solutions, tilting collaborative innovation toward exploitation of established codebases rather than exploration of new functionality. This paper provides a rare instance of causal field evidence on LLM effects, given the speed at which GenAI has exploded across the knowledge economy.

Evolutionary Reinforcement Learning (ERL), which integrates Evolutionary Algorithms (EAs) and Reinforcement Learning (RL) for optimization, has demonstrated remarkable performance advancements. By fusing both approaches, ERL has emerged as a promising research direction. This survey offers a comprehensive overview of the diverse research branches in ERL. Specifically, we systematically summarize recent advancements in related algorithms and identify three primary research directions: EA-assisted Optimization of RL, RL-assisted Optimization of EA, and synergistic optimization of EA and RL. Following that, we conduct an in-depth analysis of each research direction, organizing multiple research branches. We elucidate the problems that each branch aims to tackle and how the integration of EAs and RL addresses these challenges. In conclusion, we discuss potential challenges and prospective future research directions across various research directions. To facilitate researchers in delving into ERL, we organize the algorithms and codes involved on https://github.com/yeshenpy/Awesome-Evolutionary-Reinforcement-Learning.

Recent work has proposed Wasserstein k-means (Wk-means) clustering as a powerful method to classify regimes in time series data, and one-dimensional asset returns in particular. In this paper, we begin by studying in detail the behaviour of the Wasserstein k-means clustering algorithm applied to synthetic one-dimensional time series data. We extend the previous work by studying, in detail, the dynamics of the clustering algorithm and how varying the hyperparameters impacts the performance over different random initialisations. We compute simple metrics that we find to be useful in identifying high-quality clusterings. We then extend the technique of Wasserstein k-means clustering to multidimensional time series data by approximating the multidimensional Wasserstein distance as a sliced Wasserstein distance, resulting in a method we call 'sliced Wasserstein k-means (sWk-means) clustering'. We apply the sWk-means clustering method to the problem of automated regime classification in multidimensional time series data, using synthetic data to demonstrate the validity and effectiveness of the approach. Finally, we show that the sWk-means method is able to identify distinct market regimes in real multidimensional financial time series, using publicly available foreign exchange spot rate data as a case study. We conclude with remarks about some limitations of our approach and potential complementary or alternative approaches.

Interactive assistance systems typically provide feedback after an action has been completed, supporting error recovery but not preventing the error itself. We present TRAFA, a real-time predictive feedback system for procedural tasks that intervenes before errors are committed. TRAFA operationalizes predictive feedback through a Track-Forecast-Act framework that tracks hand and object state, forecasts user motion conditioned on scene context, and triggers feedback when a predicted action is likely to violate task constraints. We instantiate this pipeline in a sequential assembly setting and evaluate it through both technical benchmarking and a controlled user study against conventional reactive feedback. Our results show that predictive feedback improves task accuracy and efficiency while maintaining a comparable number of feedback events. These findings position feedback timing as a key dimension in system design and show how real-time anticipation can be integrated into interactive systems to prevent errors before they occur.

Missense variant interpretation remains challenging because pathogenicity depends on heterogeneous evidence from population frequency, evolutionary conservation, transcript context, amino acid substitution severity, prior pathogenicity predictors and protein-language-model-derived features. We present AnnotateMissense, a scalable annotation, benchmarking and genome-wide prediction framework for missense variant interpretation. AnnotateMissense integrates hg38 missense variants derived from dbNSFP v5.1 with ANNOVAR annotations, dbNSFP transcript/protein descriptors, AlphaMissense scores, ESM-derived features, conservation metrics, population-frequency variables, established pathogenicity predictors and engineered amino acid/codon-context features. Using 132,714 ClinVar-labelled missense variants, we benchmarked machine-learning and deep-learning models under controlled feature configurations. The full 303-feature benchmark set achieved the strongest performance with XGBoost, reaching mean MCC = 0.9411 and ROC-AUC = 0.9950 across stratified five-fold cross-validation. Restricted naive and location-oriented feature sets achieved lower best MCC values of 0.4989 and 0.5113, respectively. Circularity-controlled ablations showed that removing prior-predictor, population-frequency and clinically overlapping evidence reduced performance, whereas excluding AlphaMissense and ESM-derived features alone had minimal effect. Temporal ClinVar validation on newly observed pathogenic/benign variants achieved MCC = 0.7613, accuracy = 0.8798 and F1-score = 0.8750. The final model was applied to 90,643,830 hg38 missense variants to generate AnnotateMissense pathogenicity scores and binary prediction labels. Code and outputs are available at https://github.com/MuhammadMuneeb007/CAGI7_Annotate_All_Missense and https://doi.org/10.5281/zenodo.19981867.

Mixed-motive scenarios are ubiquitous in real-world multi-agent interactions, where self-interested agents often defect for immediate rewards, overlooking the potential of altruistic cooperation to improve long-term gains and collective welfare. Peer punishment can deter defection, but as costly second-order altruism, its persistent imposition may undermine the punisher's interests. Existing approaches often struggle to effectively implement punishment to promote cooperation. To balance the efficacy and cost of punishment, we propose Adaptive Punishment for Cooperation (APC), a distributed method that determines punishment intensity based on both a dynamic punishment probability and the severity of defection. This dynamic probability substantially reduces costly and ineffective punishment while also promotes cooperation. To accurately assess defection and its severity, we use a defection awareness module, whose learning is guided by game reward. Theoretical analysis and empirical results show APC performs effectively in iterated public goods game. Empirically, APC also significantly outperforms existing baselines across sequential social dilemmas, learning rational and effective punishment policies that foster cooperation by strategically deterring defection.

We introduce a physics-inspired continuous relaxation framework that yields substantially improved solutions for NP-hard combinatorial optimization problems, including Quadratic Unconstrained Binary Optimization (QUBO), binary sparse coding, and planted-solution Ising models. By parameterizing discrete binary variables as continuous wave-like states on the complex unit circle, we inherently smooth highly non-convex energy landscapes. We show that representing binary variables as complex phases reveals an implicit regularization mechanism that promotes convergence toward discrete states. Extracting this mechanism yields significant improvements even within standard real-valued optimization frameworks, using this regularizer explicitly. Empirically, this regularization yields vastly higher ground-state convergence rates than standard real-valued alternatives. Our models achieved zero error in large-scale 160x160 QUBO tasks under severe noise (sigma=0.25), and outperformed traditional algorithms (OMP and LASSO) in underdefined sparse coding with perfect recovery at sigma=0.15. The solver's robustness was further validated by recovering exact ground-state configurations in 8 out of 11 rigorously engineered planted-solution benchmarks.

Data streams in real-world industrial scenarios often contain transitional operating conditions that are uncovered during offline training, leading to significant distribution shifts. To bridge the gap between static offline models and dynamic online data, a novel asymmetric adaptation-based fault diagnosis method is proposed in this paper. Specifically, in the offline stage, we employ domain generalization techniques to extract domain-invariant features from multiple stable conditions and construct robust normalized fault prototypes as reference anchors. Subsequently, during online inference, we design an online test-time adaptation method based on a periodic prototype re-projection mechanism to dynamically update prototype positions. Furthermore, we utilize the geometric distribution derived from anchors to guide the updates of classifiers and adopt an asymmetric learning rate strategy for the feature extractor and classifier. The proposed approach ensures rapid adaptation to new transitional conditions while preserving the discriminative power inherited from the offline domain generalization initialization. Experimental results demonstrate that this mechanism effectively leverages offline generalized knowledge to guide online inference, significantly improving robustness in non-stationary environments.

Large Language Model (LLM)-based code analysis tools are adopted to automate software documentation tasks. However, the scalability of these approaches to real codebases, where Intermediate Representations (IR) exceed LLM context limits, remains underexplored. This paper introduces an agentic architecture with context engineering for automated UML diagram generation from source code repositories. It employs a hierarchy of five specialized agents: PlannerAgent, AnalyzerAgent, DiagramAgent, CorrectorAgent and DependencyAnalyzerAgent, built on the Claude Agent SDK, each addressing a distinct cognitive subtask. A deterministic, importance-weighted IR compaction layer transforms full project IRs into diagram-specific views guaranteed to fit within token constraints, requiring no LLM calls and completing in milliseconds. Thus, we evaluate the system across 12 open-source repositories in 4 programming languages (Java, JavaScript, PHP, Python) and 7 UML diagram types, producing 84 observations assessed on 5 automated metrics. Results demonstrate high syntactic validity (mean: 91.5%, with component and deployment diagrams reaching 100%), strong relationship precision (mean: 0.858) and consistent structural quality (mean: 81.7/100, with cross-language variance of 3.1 points). Entity recall averaged 0.313, reflecting deliberate architectural prioritization over exhaustive coverage. A sensitivity analysis (31 to 4,578 IR entities) confirms that quality scores remain stable regardless of scale.

Selecting the most suitable algorithm for a given problem instance remains a challenging task, particularly in online or dynamic environments where problem characteristics evolve over time. Relying solely on instantaneous performance metrics can result in a reactive and unstable behaviour, often leading to suboptimal algorithm switching. This paper introduces a computationally efficient approach for aggregating an algorithm's performance across multiple problem instances that is fairly immune to erratic variations in instance features. Inspired by features inherent to Reinforcement Learning (RL), this technique encapsulates rewards and penalties into a latent yield that, in turn, triggers exploitation and exploration, consequently resulting in adaptive algorithm switching. The proposed technique employs island models, inspired by Genetic Algorithms, to facilitate parallel exploration and performance exchanges among algorithm populations inhabiting local repertoires. Experimental evaluations on sorting algorithms and robotic obstacle avoidance tasks demonstrate the feasibility and effectiveness of the approach, highlighting its potential in domains where adaptive algorithm selection is critical.

Stochastic Dominance (SD) theory provides a rigorous framework for selecting superior assets tailored to the asset allocation needs of investors with varying risk preferences (i.e., risk-averse, risk-seeking, and risk-neutral). However, traditional stock clustering methods typically rely on geometric metrics such as Euclidean distance, which often fail to effectively capture the intrinsic risk dominance relationships among assets. To address this limitation, this paper proposes an innovative clustering analysis framework based on SD test statistics. Methodologically, this study deeply integrates SD theory with machine learning algorithms. Transcending the limitations of traditional reliance on geometric distance, we innovatively utilize test statistics from first-, second-, and third-order SD to construct a "Stochastic Dominance Coefficient Matrix." Building upon this matrix, we modify the classic K-means and Hierarchical Clustering algorithms. Specifically, we derive 12 distinct algorithm variants tailored to different orders of SD relationships. Simultaneously, we construct the SD-SC coefficient and the SD-DBI index as specialized validity indices to evaluate the clustering performance. Empirically, we analyze constituent stock data from a representative developed market (the US NASDAQ Index) and an emerging market (China's CSI 100 Index). The results verify the effectiveness and robustness of the proposed method. Furthermore, we apply the clustering results to the modification of the Single Index Model and the construction of Global Minimum Variance Portfolios (GMVP). The findings demonstrate that the proposed method effectively facilitates customized asset allocation for investors, holding significant theoretical value and practical implications.