Logged advertising auctions make offline reserve-price evaluation attractive but risky. Replay tables can identify policies with large apparent yield gains, yet they can also hide weak threshold support, multiple-comparison effects, subgroup harm, and bidder-response uncertainty. Existing replay and off-policy evaluation methods estimate or rank policy values, but they do not directly answer the operational question of whether the available evidence is strong enough to justify validation. This paper develops a support-aware offline decision framework for reserve-policy selection. Rather than outputting a single point-estimate winner, the framework converts logged evidence into a conservative decision object consisting of certified policies, statistically dominated alternatives, and unresolved candidates requiring further validation. The main theoretical result gives a unified finite-catalog guarantee showing that, under simultaneous uncertainty control and conservative support gates, the framework preserves the best gate-passing policy while eliminating only policies with certified regret. Supporting results characterize support-localized replay generalization, establish information-theoretic threshold-resolution limits, and quantify when heterogeneous bidder response can overturn localized replay rankings. Experiments on iPinYou real-time-bidding logs show that the leading reserve rule achieves a 47.66% replay lift in season two, a 40.71% simultaneous lower-bound lift, and a 43.87% frozen out-of-time replay lift in season three. The framework reduces a 19-policy catalog to a two-policy validation shortlist while certifying non-harm across 44 advertiser, exchange, and region segments. The results support the central claim that offline reserve-policy evaluation should produce certified validation decisions rather than point-estimate rankings alone.

Sampling from discrete distributions with multiple modes and energy barriers is fundamental to machine learning and computational physics. Recent discrete neural samplers like MDNS suffer from mode collapse and fail to sample high-energy barrier regions between modes, which is critical for free energy estimation and understanding phase transitions. We propose Metadynamics Discrete Neural Sampler (MetaDNS), a general framework integrating well-tempered metadynamics into discrete diffusion or autoregressive samplers. By maintaining an adaptive, history-dependent bias potential along selected low-dimensional coordinates, MetaDNS forces exploration of previously inaccessible regions, enabling free energy reconstruction infeasible with standard neural samplers due to a lack of high-energy samples. On challenging low-temperature benchmarks including Ising, Potts, and the copper-gold binary alloy, MetaDNS reproduces the thermodynamic distribution. Compared to MCMC-based metadynamics, MetaDNS also achieves comparable exploration requiring fewer bias deposition steps.

We describe an adaptive market-making architecture that preserves the analytical structure of the Avellaneda--Stoikov framework while introducing a successor measure-style adaptation mechanism. In our paper we keep Avellaneda--Stoikov fast Hamilton--Jacobi--Bellman structure and make it adaptive to changing market regimes and trading objectives. The central idea is to separate market dynamics from the trading objective. The market state determines a low-dimensional set of Avellaneda--Stoikov parameters, while recent realized rewards determine a low-dimensional objective vector. The HJB forward map then converts this objective into optimal bid and ask quotes through a scalarization of future reward features.

Connecting large language models (LLMs) to defensive enforcement requires more than asking a model whether an attack is happening. A defender must decide which model outputs may change the system state, which outputs must be rejected, and how failures should be recorded. We present PocketAgents, a manifest-driven library of autonomous defense agents. Each agent is installed as three data files: a manifest, a prompt, and a runtime context. The shared runtime gives the agent bounded telemetry access and accepts only typed reports whose requested action appears in the manifest. We implemented PocketAgents on top of a cyber arena (Perry), a cyber-deception testbed, and evaluated two agents, Command and Control and Exfiltration, in 18 closed-loop trials of a DarkSide-inspired attack on a small enterprise topology. Thirteen trials produced validated network-block actions and contained the attack; four failed schema validation; one produced a valid no-action decision. The experiments show that a typed boundary makes LLM-driven defense measurable, extensible, and attributable.

Hyperspectral super-resolution (HSR) reconstructs a high-spatial-resolution hyperspectral image by fusing a low-resolution hyperspectral image (LR-HSI) with a high-resolution multispectral image (HR-MSI). In the absence of real-world paired data, HSR methods are evaluated almost exclusively on synthetic experiments derived from hyperspectral datasets through Wald's protocol. Despite the protocol's widespread adoption, its practical implementation varies markedly across research works, typically relying on a single (usually Gaussian) or very few point spread functions (PSFs), one or two spectral response functions (SRFs), and a couple of spatial downsampling factors. As a result, reported performance figures are difficult to compare across the literature, in addition to being often difficult to reproduce; furthermore, they may not generalize across realistic sensing conditions. We introduce HyperBench, a unified and extensible framework that standardizes synthetic experimentation for HSR. HyperBench supports diverse degradation configurations spanning ten PSFs, four SRFs derived from operational multispectral sensors, configurable spatial downsampling factors, and matched additive white Gaussian noise; its goal is to automate large-scale evaluation and structured logging. By decoupling model development from experimental design, the framework enables reproducible, apples-to-apples cross-method comparison with minimal friction. We use HyperBench to evaluate six recently proposed HSR methods across a 70-configuration sweep on four widely used hyperspectral scenes and observe that the inter-method PSNR spread widens from approximately 5 dB on the easiest PSF to over 13 dB on the hardest - a fragility that is structurally invisible to the prevailing single-configuration evaluation protocol. HyperBench code is available at https://github.com/ritikgshah/HyperBench .

The rapid growth of electric vehicles is shifting the main constraint on transport electrification from vehicle adoption to the deployment and operation of charging infrastructure. Charging-network design requires decisions across three interdependent layers: Planning, which determines where and how much infrastructure to build; Scheduling, which governs charging dispatch, pricing, and grid interaction; and Behavior, which captures how users choose stations, charging times, and charging durations. Existing studies have advanced each layer substantially, but the literature remains fragmented, and cross-layer interactions are often treated through simplifying assumptions. This survey develops a three-layer Planning-Scheduling-Behavior (PSB) framework to organize EV charging research according to decision horizon, actor objective, and coupling structure. We further identify a fidelity-tractability tradeoff, termed the PSB trilemma: each layer is computationally difficult in isolation, and realistic integration across layers generally requires reducing the fidelity of at least one layer. Reviewing the three pairwise-coupling literatures - Planning-Scheduling, Scheduling-Behavior, and Planning-Behavior - we show that the omitted third layer is typically fixed exogenously or represented by a static aggregate surrogate. These simplifications enable tractability but impose distinct costs: they can obscure long-term investment feedback, temporal grid and emissions dynamics, or heterogeneous user response and equity outcomes. Building on this diagnosis, we identify open challenges in emerging charging technologies, behavioral incentives, equity metrics, and city-scale learning-based methods that balance fidelity, interpretability, and policy relevance.

AI is now embedded in healthcare, finance, policy, and many other domains, yet genuine human-AI synergy - combined performance that exceeds what either party achieves alone - is uncommon. Meta-analyses show that AI assistance tends to improve human performance compared to working alone, but studies finding true synergy are scarce. We call this persistent shortfall the synergy gap. Most current work treats human-AI combination as an engineering problem and concentrates on interpretability, trust calibration, or interface design. These matter, but they cover only part of what determines whether combination works. Closing the synergy gap, we argue, requires explicit engagement with a wider design space. We map that space through six interconnected elements: sociotechnical context, decision-making frameworks, human decision participants, AI capabilities, interaction, and holistic evaluation. For each element, we describe what it covers, how it shapes the others in practice, and what it implies for design. The result is a shared vocabulary for practitioners building hybrid systems, an analytical lens for researchers studying combination patterns, and a starting point for evaluators interested in the full quality of human-AI decision-making rather than accuracy alone.

When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is essential for treatment and surgical planning. However, ischemic stroke lesions vary widely in shape, size, and location, and in grayscale MRI modalities such as T1W they may resemble surrounding brain structures. This makes lesion detection and segmentation a challenging task for clinicians. This study introduces a novel VRU-Net architecture, derived from visual features, residual connections, and a U-shaped network, for detecting and segmenting ischemic stroke lesions in 3D magnetic resonance imaging scans. The proposed method first uses a modified VGG model to identify ischemic stroke in separate 2D slices. Then, a U-shaped segmentation model with residual blocks segments the lesion in each slice. This procedure is applied independently to the axial, sagittal, and coronal planes, and the final output is generated by aggregating the three segmentation results. To improve both performance and processing speed, a high-performance classifier is applied before the segmentation model in a sequential framework. This strategy reduces unnecessary segmentation of non-lesion slices and improves overall accuracy. In addition, decomposing 3D images into 2D slices reduces model complexity while allowing information from three anatomical planes to support more accurate lesion localization. The proposed model is trained on the Anatomical Tracings of Lesions After Stroke dataset and outperforms state-of-the-art models in terms of accuracy and Dice coefficient. Moreover, the segmentation output provides feedback that helps the classification model reduce false-positive predictions.

Existing binary corpora typically capture only one or two axes of binary variation: they either provide cross-compiler builds without a temporal axis, or CVE labels for single-build binaries. None combine cross-build diversity, cross-version history, and CVE labels into a queryable structure. We present ASSEMBLAGE-DEEPHISTORY, which consolidates these dimensions into a unified framework where every binary's compilation context, source code, vulnerable functions, and package version are stored as first-class metadata. ASSEMBLAGE-DEEPHISTORY comprises 73,610 binaries spanning 248 open-source projects, compiled across GCC, Clang, and MSVC at multiple optimization levels on Linux and Windows, with multi-year historical builds. Each binary is indexed in a database that links it to its source code, functions, debug info, variant builds, historical versions, and vulnerable functions. Three analyses demonstrate this structure's value: (1) a three-stage LLM benchmark (recognition, strategy-guided detection, and cross-build transfer) to test whether LLMs reason about binary vulnerabilities or pattern-match on build-specific artifacts; (2) a comparison of MalConv embeddings, jTrans function embeddings, and TLSH fuzzy hashes quantifying how same-package versions cluster in each space; and (3) a Bayesian regression decomposing binary similarity into contributions from temporal distance, file changes, and commits.

Worked examples are step-by-step solutions to problems in a specific domain, offered to students to acquire domain-specific problem-solving skills. The effectiveness of worked examples could be enhanced by combining them with self-explanations, which ask students to explain rather than passively study each problem-solving step. The main challenge of this approach is assessing the correctness of the student's explanations. In the prevailing approach, student explanations are judged by their semantic similarity to an instructor's or domain expert's explanation. Given recent advances in LLM-based automated scoring, it remains unclear whether semantic similarity methods are still the most effective technique to automatically score textual student responses like essays or code explanations. Comparing these methods also requires quality datasets that offer distinctive features such as balanced class distributions and domain-specific labeled data for automated scoring tasks. In this paper, we present a rigorous comparison between LLMs and semantic similarity used for automated scoring, framed as a binary classification task.

We study the problem of selecting covariates for unbiased estimation of the total causal effect.Existing approaches typically rely on global causal structure learning over all variables, or on strong assumptions such as causal sufficiency - where observed variables share no latent confounders - or the pretreatment assumption, which limits covariates to those unaffected by the treatment or outcome. These requirements are often unrealistic in practice, and global learning becomes computationally prohibitive in high-dimensional settings.To address these challenges, we propose a novel local learning method for covariate selection in nonparametric causal effect estimation that avoids both the pretreatment and causal sufficiency assumptions. We first characterize a local boundary that contains at least one valid adjustment set whenever one exists for identifying the causal effect, and then develop local identification procedures to efficiently search within this boundary.We prove that the proposed method is sound and complete. Experiments on multiple synthetic datasets and two real-world datasets show that our approach achieves accurate causal effect estimation while substantially improving computational efficiency.

Frontier large language models are increasingly deployed as orchestration backbones for biological research workflows, yet no shared evidence base exists for comparing their refusal behaviour on legitimate research prompts. RefusalBench, introduced here, is a matched-triple benchmark of 141 prompts in 47 bundles that holds task framing constant while varying only biological risk tier (benign, borderline, dual-use), enabling tier-conditioned comparisons robust to subdomain confounding. A 15-prompt should-refuse positive-control module establishes per-model calibration floors; three models fail to refuse even these prompts. Across 19 frontier models in the May 2026 snapshot, strict refusal rates span 0.1% to 94.6% on identical prompts. Jurisdiction does not predict refusal in this snapshot (Mann-Whitney U, p = 0.393; EU n = 1, US bimodal); provider identity does, with Anthropic's API stack predicting refusal at OR = 21.03 (95% CI: 14.58-30.34 prompt-clustered; 5.70-77.55 under model-clustered GEE). This effect is best read as access-path-level rather than model-weight-level: 99.8% of Anthropic's strict refusals carry the same safety_policy adjudicated reason code, consistent with a small set of canonical refusal templates rather than case-by-case model reasoning. Strict refusal rate misranks safety calibration: Grok 4.20 achieves the highest tier discrimination (Youden's J = 0.787) while ranking only seventh by overall refusal rate, and Claude Opus 4.7's J dropped 65% from prior versions with no improvement in dual-use detection. Nine of 18 frontier models exhibit a hedge-but-help partial-compliance pattern at dual-use tier that binary refusal metrics cannot detect.

Multimodal large language models (MLLMs) remain vulnerable to transfer-based targeted attacks, where perturbations optimized on open-source surrogate encoders can generalize to closed-source MLLMs. A key challenge for improving adversarial transferability is to effectively capture the intrinsic visual focus shared across different models, such that perturbations align with transferable semantic cues rather than surrogate-specific behaviors. However, existing methods suffer from spatial-domain feature redundancy and surrogate-specific gradient signals, thereby hindering cross-model transferability. In this paper, we propose FRA-Attack, which addresses both challenges from a unified frequency-domain regularization perspective. For feature alignment, a high-pass DCT objective on patch features suppresses redundant global structures and concentrates the loss on the high-frequency band that carries the MLLMs' intrinsic visual focus. For gradient optimization, we introduce Frequency-domain Gradient Regularization (FGR), a \textit{model-agnostic} low-pass regularizer that modulates the surrogate gradient using only the geometric frequency coordinate, \textit{i.e.}, no surrogate-derived statistic is involved, so that FGR is model-agnostic by construction, removing surrogate-specific high-frequency artifacts while preserving transferable low-frequency directions. Together, the two components form a unified frequency-domain treatment of transferability. Extensive experiments on $15$ flagship MLLMs across $7$ vendors show that FRA-Attack achieves superior cross-model transferability, particularly with state-of-the-art performance on GPT-5.4, Claude-Opus-4.6 and Gemini-3-flash.

The proliferation of large language models has introduced a new paradigm of synthetic political communication in which narratives may be generated, semantically coordinated, and strategically disseminated across platforms at scale. We present a cross-platform framework for detecting synthetic political narratives using four coordination signals -- lexical diversity D(C), temporal burstiness B(C), rhetorical repetition R(C), and semantic homogenization H(C) -- combined into a Synthetic Narrative Coordination Score SNC(C). We apply the framework to a corpus of 353,223 records spanning six geopolitical event windows collected from six Telegram channels and nine Reddit communities (2023--2026). Results show that IntelSlava exhibits the lowest lexical diversity (MATTR 0.52--0.54), the highest burstiness (B=+0.48 to +0.73), and the highest rhetorical overlap with peer channels (Jaccard 0.12), ranking first in the composite SNC(C) on four of six event windows (SNC 0.45--0.60). Rybar ranks last on all windows despite its high semantic homogenization, because its Russian-language output yields high lexical diversity and near-zero rhetorical Jaccard with English-language channels -- demonstrating that no single indicator is sufficient for coordination detection. Multi-dimensional SNC(C) scoring provides a more robust and interpretable signal than any individual metric.

Kolmogorov-Arnold Networks (KANs) approximate multivariate functions using learnable univariate edge functions, typically parameterized by B-spline bases. Although effective, spline-based implementations can be computationally expensive. A modified version of KANs, called FastKAN, improves efficiency by replacing splines with Gaussian radial basis functions (RBFs), but it relies on a fixed kernel and shape parameter. In this work, we extend the RBF-based KAN framework by introducing a broader family of radial basis kernels and by initializing the kernel shape parameter using leave-one-out cross-validation (LOOCV). To the best of our knowledge, this is the first study that integrates LOOCV-based kernel scale estimation with deep KAN training. We also introduce Matérn and Wendland kernels into the KAN framework for the first time, enabling more flexible basis representations beyond the Gaussian kernel used in FastKAN. The LOOCV estimate provides a data-driven initialization of the kernel scale, which is subsequently refined during network training. The proposed adaptive RBF-KAN is evaluated on several two-dimensional benchmark functions. The results highlight the importance of kernel selection and adaptive shape parameters, with different kernels showing advantages for smooth functions, discontinuities, and oscillatory patterns. Overall, combining LOOCV-based initialization with adaptive kernel learning provides a practical strategy for improving RBF-based KAN models.

Glaciers play a critical role as freshwater reserves and indicators of climate change, yet their automatic delineation, especially for debris-covered glaciers, remains challenging due to spectral similarity with surrounding terrain. This study introduces CryoNet, a deep learning framework that leverages a rich multi-modal dataset combining Sentinel-2 optical imagery, DEM-derived topographic variables, spectral indices, Principal Component Analysis (PCA), InSAR coherence and phase, tasseled-cap features, and GLCM texture to discriminate clean-ice glaciers, debris-covered glaciers, and glacial lakes. CryoNet is an encoder-decoder CNN with nested skip connections and spatial-channel Squeeze-and-Excitation (scSE) attention, built upon a ResNet101 encoder to capture hierarchical contextual and spatial features. The study is conducted in the Poiqu Basin in the central Himalaya, and transferability is evaluated by applying the trained model to the Mont Blanc Massif in the Alps. We additionally analyse the importance of each data layer in improving glacier mapping performance. The proposed model achieves an overall IoU of 90.52%, mean Recall of 98.08%, and mean Precision of 92.26%. For debris-covered glaciers specifically, CryoNet obtains an IoU of 90.46%, a recall of 95.79%, and a precision of 94.21%. Across both per-class and overall metrics, CryoNet surpasses DeepLabV3+, SegFormer, and U-Net, taken as state-of-the-art (SOTA) references, demonstrating its effectiveness for robust glacier mapping in complex high-mountain environments.

Steganalysis models excel on benchmark datasets but struggle in the wild when analyzed images are produced by a processing pipeline unseen during training. This problem known as Cover Source Mismatch (CSM) is particularly hard in realistic settings where practitioners (1) have access to only a small, unlabeled dataset, (2) are unsure of the processing techniques applied to these images, and (3) lack information on the proportion of covers and stegos in that set. To answer this challenge, we introduce TADA (Target Alignment through Data Adaptation), a framework learning to emulate the unknown processing pipeline from a small unlabeled target set. This architecture is trained with a loss combining residual covariance alignment, residual distribution matching, and a $\ell^2$ loss constraining the emulator to produce realistic images. Across toy and operational targets, TADA yields substantial gains in robustness to CSM and improves operational generalization compared to strong holistic and atomistic baselines. Additional resources are available at this link: https://github.com/RonyAbecidan/TADA

Protein-protein interactions (PPIs) govern nearly all cellular processes, yet computational methods for identifying binding partners typically produce ranked predictions without mechanistic justification. This creates a fundamental barrier to adoption because biologists cannot assess whether predictions reflect genuine biochemical insight or spurious correlations. We present \textbf{Protein Thoughts}, a framework that reformulates PPI discovery as an interpretable search problem with explicit reasoning. The system decomposes binding evidence into four biologically meaningful signals: sequence similarity reflecting evolutionary relationships, structural complementarity capturing geometric fit, interface balance, and chemical compatibility encoding residue-level interactions. Rather than collapsing these signals into an opaque score, we preserve their individual contributions through a transparent value function that enables both ranking and auditing. To navigate large candidate spaces efficiently, we introduce hypothesis-guided entropy-regularized Tree-of-Thoughts search. A fine-tuned language model generates search directives from embedding-derived features, classifying candidates as high-priority, exploratory, or skippable. These directives condition a Boltzmann policy that balances exploitation with entropy-driven exploration, while hypothesis-aware pruning prevents premature abandonment of promising candidates. For candidates exhibiting score disagreement, hypothesis-conditioned embedding-space flow matching transports protein embeddings toward the binder manifold. On the SHS148k benchmark, Protein Thoughts achieves mean best-binder rank of 11.2 versus 47.7 for an entropic tree search baseline, a 76% improvement, and for binding prediction the trained value function achieves $91.08 \pm 0.19$ Micro-F1, outperforming existing PPI methods on the same dataset.

Graph Partitioning is a critical problem in numerous scientific and engineering domains including social network analysis, VLSI design, and many more. Spectral methods are known to produce quality partitions while minimizing edge cuts for a wide range of problems. However, the computational cost associated with the calculation of the Fiedler vector, an eigenvector associated with the second smallest eigenvalue of the graph Laplacian, remains a significant bottleneck due to memory issues and computational costs. In this paper, we present an accelerated approach to spectral bisection partitioning by replacing the traditional eigenvalue calculation with a simple artificial neural network model to approximate the Fiedler vector. We demonstrate that our approach achieves partitioning quality comparable to spectral bisection while significantly reducing the computational overhead, making it more scalable and efficient for large-scale problems

Many complex systems can be modeled by temporal networks, whose organization often evolves through distinct structural phases. Detecting the change points that delimit these phases is both important and challenging. In this work, we extend the conditional entropy of heat diffusion from static graphs to temporal networks and study its properties. We provide an upper bound and explain how discrepancies from it arise from the presence of asymmetric temporal paths. Moreover, we show that this quantity is monotone in time, yielding an information-theoretic analog of the second law of thermodynamics for inhomogeneous diffusion on temporal networks. We then introduce a local version of conditional entropy, designed to probe diffusion over finite temporal windows, and show that it provides an informative signal for change-point detection in continuous-time temporal networks. We evaluate the proposed methodology on synthetic benchmarks, including comparative experiments with existing nonparametric baselines in the snapshot setting, and then apply it to a real-world temporal contact network from a French primary school. Finally, we show how to use detected change points to perform community detection on targeted sub-intervals, improving the quality and interpretability of the clustering results.

Reference-based graph compression encodes each vertex's neighbor list relative to a recent vertex, exploiting locality to compress large directed graphs. The dominant tool, WebGraph's BVGraph, fixes a single encoding pipeline and relies on a separately chosen vertex ordering -- typically URL-lexicographic or Layered Label Propagation (LLP). The interaction between ordering and encoder is rarely measured. We propose a two-stage Leiden+LLP vertex ordering -- global LLP to seed labels, Leiden community detection, then per-cluster LLP on each induced subgraph -- and study how it interacts with reference-based compression. On graphs with poor initial vertex order, reordering saves 0.3 to 5.4 bits per edge on every dataset and encoder we measured. The size of that gain is largely insensitive to the encoder: on four of five weakly ordered datasets, four independently parameterised encoders agree on the Leiden+LLP-vs-plain-LLP gain within roughly +/- 0.04 bpe. On URL-ordered web crawls, where the distributed ordering already encodes locality, adaptive encoders still benefit from reordering, but encoders tuned to URL-induced residual structure (BV-HC, CG at K>1) are mildly hurt by it. To quantify how much encoder choice matters once ordering is fixed, we contribute three reference-based encoders -- BG, CS, and CG -- that perform per-vertex cost-optimal selection from up to 28 candidate decompositions. Each is run under its own best-tested ordering. The best of the three improves over BVGraph high-compression by 2-9% on every dataset tested, with the encoder-level gain consistently smaller than the ordering-level gain on weakly ordered datasets. The encoder framework also yields a self-delimiting bitstream that supports low-overhead random access.

Atmospheric visibility is a critical variable for transportation safety and air quality management, however, accurate prediction remains challenging due to the complex interactions between meteorological conditions and air pollutants, as well as the rarity of low-visibility events. This study introduces a machine learning framework to nowcast visibility in six major South Korean cities. To handle the imbalance in the 2018-2020 training data, we applied the Synthetic Minority Over-sampling Technique with Nominal and Continuous (SMOTENC) and Conditional Tabular Generative Adversarial Network (CTGAN). An ensemble approach combining machine learning and deep learning models was then used and evaluated on a 2021 test dataset. The results revealed a marked decline in predictive performance in the test set compared to the cross-validation phase. This degradation was attributed to a distributional shift between training and testing periods, which was quantitatively confirmed by measuring the Wasserstein distance of the most influential feature identified by SHAP analysis. In general, this study presents a methodology that aims to simultaneously address the dual challenges of data imbalance and temporal distributional shifts, and emphasizes the necessity of accounting for evolving external environmental factors when implementing nowcasting models on time-series data.

Graph neural networks (GNNs) are increasingly used to model biological systems, yet the reliability of post-hoc explanation methods for recovering meaningful molecular mechanisms remains unclear. Here, we systematically evaluate four widely used approaches: Saliency Attribution (SA), Integrated Gradients (IG), GNNExplainer, and Layer-wise Relevance Propagation (LRP) for identifying disease-relevant structure in breast cancer RNA-seq data projected onto a protein-protein interaction network. Using synthetic benchmarks with known ground-truth motifs, we show that explanation methods recover distinct signal organizations: SA performs best for sparse single-node drivers, whereas IG and LRP preferentially recover distributed pathway-like and cascade-like signals. In TCGA BRCA data, we identify a consistent topological signature of disease-associated hubs in which attribution peaks in the immediate 1-hop neighborhood and decays across successive network shells, a pattern most pronounced for IG and LRP and associated with strong enrichment of known cancer hubs. We further observe a trade-off between local hub enrichment and global gene ranking performance, with IG optimizing local enrichment and SA achieving superior global discrimination. Motivated by these complementary behaviors, we introduce a framework combining a shell-based hub score with consensus ranking across explainers. Consensus scores improve prioritization of canonical cancer genes (TP53, BRCA1, ESR1, MYC), reduce dependence on node degree, and, especially when tuned, outperform individual methods. Pathway enrichment further reveals improved recovery of biologically coherent cancer programs, including ERBB2, RTK, MAPK, immune, and cytokine signaling. Together, these results demonstrate that topology-aware integration of graph explanations can improve biological interpretability and biologically relevant molecular recovery.

Event cameras have emerged as a high-bandwidth, low-latency sensing modality for safety-critical perception in automated driving systems (ADS), offering microsecond temporal resolution, 120-140 dB dynamic range, and intrinsic absence of motion blur. However, no task-agnostic quality metric currently operates directly on the asynchronous event stream: state-of-the-art proxies require a downstream task (e.g., detection accuracy, tracking error) to assess stream integrity, which is incompatible with the certification requirements of ISO 21448 (SOTIF) and ISO/PAS 8800:2024. The recent BiasBench benchmark (CVPR 2025) explicitly identifies this gap. This work proposes a unified algebraic framework that lifts the Pearson Correlation Coefficient (PCC), historically used in two prior works for redundancy filtering and ROI selection on frame-based images, to the three standard event representations: Time Surface, Event Frame, and Voxel Grid. The framework yields three metrics: (i) r-TS for stream integrity monitoring against an ego-motion-predicted Time Surface, (ii) r2-EF for adaptive ROI selection requiring only integer comparisons, and (iii) r-VG for temporal redundancy gating. A structural isomorphism is established between the contrast-threshold mechanism of the event camera (|Delta L| >= C) and the PCC-based change criterion, the three lifted metrics are formalized, and pipeline latency and information loss are analyzed symmetrically against the raw stream. Illustrative behavior of each metric is demonstrated on a procedural-synthetic event stream, generated by direct simulation of the emission model rather than drawn from any real or video-derived dataset, including a tunnel-dip integrity-anomaly scenario in which r_C drops from 0.93 (coherent flow) to below 0 (alarm). An explicit epistemic convention ([ESTABLISHED], [SOLID], [HYPOTH.], [OPEN]) delineates the status of every contribution.

Grid-based neural networks such as convolutional autoencoders are widely used in dimension reduction-based surrogate models for computational fluid dynamics. In recent years, the use of coordinate-based approaches like conditional neural fields has emerged. Their independence of the spatial discretization is a beneficial feature for various applications in computational fluid dynamics. This paper discusses the spatio-temporal prediction of aircraft ditching loads using a conditional neural field approach. The model is evaluated using two datasets for the dynamic loads of the fuselage of a DLR-D150 aircraft, one of which relates to a single fixed spatial discretization and the other that includes data from different discretizations. When paired with a long short-term memory (LSTM) network in the latent space, the neural field-based model achieves a spatio-temporal prediction accuracy for the first data set that is close to that of grid-dependent convolutional autoencoder-based models, and with significantly less parameters. Results for the second data set demonstrate the ability of the neural field-based approach to reconstruct ditching loads accurately for heterogeneous spatial discretizations. This allows for flexible use of training datasets generated for different geometries and/or discretizations, as well as the use of the surrogate model to predict loads for different configurations.

Large Language Model (LLM) agents are increasingly proposed to automate offensive security tasks, with recent studies reporting near human-level success rates in Capture-the-Flag (CTF) challenges. We here revisit these results, providing a second look at these claims. We engineer different agent architectures of increasing complexity and modularity on 30 web-based CTFs challenges spanning 14 vulnerability classes. We instantiate these agents with multiple LLM backbones, and compare them with claude-code, a general-purpose agent that automatically determines its internal architecture. Our evaluation yields three main findings. First, claude-code achieves performance comparable to the engineered architectures (19/30 solved tasks), suggesting that general-purpose agents are strong baselines for offensive security tasks. Second, both our architectures and claude-code struggle in the same challenge categories, revealing persistent barriers that keep current agents below human-level capability. Third, by leveraging our manually designed architectures we can systematically measure the impact of additional components, finding that structured orchestration of specialized roles outperforms monolithic designs, improving run-to-run consistency, and reducing execution costs.

As distributed model training scales to span hundreds of thousands of GPUs, scale-out networks face unprecedented performance and efficiency demands. NVIDIA Spectrum-X Ethernet has been designed from the ground up to achieve predictable and stable network performance with high utilization and low latency. This paper presents the Spectrum-X multiplane architecture, which replaces hierarchical depth with topological parallelism, and introduces hardware-accelerated load balancing in NICs and switches as the key architectural approach to provide fast reaction to highly dynamic network conditions at the microsecond timescales that AI training workloads demand. We describe the motivation, design principles, evaluation methodology and performance on state-of-the-art benchmarks, as well as the lessons we learned from deploying and debugging Spectrum-X networks in large-scale systems. Our evaluation highlights production-grade AI infrastructure performance across three core dimensions: 98% of the theoretical line rate with low jitter-free latency; strong cross-tenant isolation for concurrent workloads; robust, capacity-proportional bisection bandwidth and 7% latency increase for 10% fabric link failures; and rapid reaction to host and fabric link flaps during LLM training workloads.

The growing use of information hiding in network streaming media for covert communication poses a significant security threat, necessitating the development of robust detection technologies. However, existing steganalysis methods for network voice streams mostly rely on data distributions in specific scenarios, making it difficult to adapt to the practical detection needs of non-homologous data distributions. Through Hessian analysis, we find that the loss landscapes of mainstream models are dominated by numerous saddle points and sharp local minima, rendering them highly sensitive to data distribution shifts and fundamentally limiting generalization. Therefore, we propose a new optimizer, Domain-Aware Sharpness Minimization (DASM). The core mechanisms of DASM consist of two aspects: first, it integrates domain-supervised contrastive learning with sharpness-aware optimization, explicitly preserving inter-domain feature separation while seeking flat minima; second, we design an adaptive domain gap modulation strategy that dynamically calibrates the optimization loss weights by sensing the real-time feature separability of different domains. Extensive experimental results demonstrate that our method outperforms the state-of-the-art methods by a large margin and achieves excellent generalization and robustness.

As multi-agent systems move from short interactions to tool-using workflows with specialized roles and persistent state, completion becomes a runtime-control problem rather than a purely generative one. This preprint studies verify-gated completion as an admission-control pattern for governed multi-agent runtimes: agents may propose completion, but a read-only verifier decides whether the claim is admitted. Ambiguous or weakly evidenced cases resolve fail-closed, while packetized state and event traces preserve an audit path. We examine one bounded reference implementation and ask what the released evidence can support about auditable, verify-gated completion. In the released verify-completed slice, the known-outcome invoked-event verify success share was 1,791/1,800 = 99.5%. This is an accounting measure over invoked verification events, not a task-completion, production-reliability, or benchmark-success rate. Task-level verify coverage is not computable; 1,762/1,801 rows came from one high-volume reporting cluster; and only 17 events were production-classified. A shadow Policy/Governance Verifier evaluation showed 1,526/1,548 = 98.58% rule agreement, 0/1,526 false-success among safe-to-proceed predictions, and blocked precision of 2/518 = 0.39%, so it remains advisory. The evidence supports a narrow conclusion: under observed conditions, a read-only verify gate plus packetized admission records made completion decisions inspectable and fail-closed. Claims about deployed operation, safety guarantees, outcome gains, task-level coverage, recovery effectiveness, or external validity remain outside scope.

Quantum error correction (QEC) is essential for building fault-tolerant quantum computers, requiring decoders that are simultaneously accurate, fast, and scalable. Most state-of-the-art neural decoders achieve high accuracy but process the full dense syndrome array of size $O(d^2 R) $regardless of the actual error rate, where d is the code distance and R is the number of measurement rounds. At physically relevant error rates (p ~ 0.1%), fewer than 5% of syndrome entries contain active detection events -- yet existing decoders process the entire syndrome volume. We introduce the Sparse Mamba Decoder (SMD), a defect-centric neural decoder that processes only the k active detection events using a 13-dimensional feature representation per defect and a Mamba state-space backbone, achieving $O(k)$ complexity. Across depolarizing, uniform circuit-level, SI1000, and Google Sycamore experimental benchmarks, SMD reduces the MWPM logical error rate by up to 49% at $d \le 5$ under SI1000 noise, runs 95-467x faster than the Tesseract near-MLD decoder and 232-463x faster than Belief Matching, and maintains nearly constant latency (24-57 us) across d = 3-9 under uniform circuit-level noise. On the Sycamore experimental dataset, the SMD ensemble matches or slightly surpasses the dense Mamba decoder of Varbanov et al. All results are obtained on commodity NVIDIA GPUs with 7.5-16M parameters, without specialized accelerators.