Despite the central role of sensor-derived measurements such as imaging traits and plasma biomarkers in biomedical research and clinical practice, existing generative models for disease prediction largely depend on event-level representations from hospital and registry data. Given the multi-factorial nature of human disease, the absence of explicit modeling of social determinants of health (SDoH), even in the limited form of ICD-coded proxies (chapters Z and V--Y in ICD-10), limits the capacity for personalized disease modeling and clinical decision support. To address this limitation, we propose a generative model with ICD-coded proxies of SDoH for \textit{in silico} modeling of disease reasoning, a conditioned latent diffusion framework that establishes the connection between multi-organ sensor data with tokenized healthcare events. Specifically, we introduce a novel geometric diffusion model to characterize the temporal evolution of complex data representation such as brain networks (region-to-region connectivity encoded in a graph), in parallel with diffusion models for tabular data from other organ systems. Together, we integrate the generative model with digitalized SDoH proxies (coined \modelname{}) for simulated intervention and reasoning of future disease trajectories. We conduct extensive experiments on the UK Biobank (UKB) dataset, which contains organ-specific imaging traits, including brain (44,834), heart (23,987), liver (28,722), and kidney (32,155), along with nearly 500k medical history sequences (age range: 25$\sim$89 years). Our \modelname{} achieves significant improvements over state-of-the-art human disease autoregressive models and imaging trait generative baselines.

Representation learning in electronic health records (EHR) has largely followed paradigms inherited from natural language processing, relying on sequence modeling and reconstruction based objectives that treat clinical labels as ground truth. However, real world clinical supervision is inherently weak, arising from heterogeneous, noisy, and institution specific labeling processes such as billing codes, heuristic phenotypes, and incomplete annotations. In this work, we propose WISTERIA, a weakly supervised representation learning framework that models labels as stochastic observations of an underlying latent clinical state. Instead of optimizing against a single supervision signal, WISTERIA constructs multiple weak supervision operators and learns representations by enforcing consistency across their induced label distributions. This multi view formulation induces an implicit denoising mechanism, allowing the model to recover clinically meaningful structure by reconciling disagreement between noisy labelers. We further incorporate ontology aware regularization in the label space to impose semantic structure over supervision signals. Empirically, WISTERIA improves predictive performance across standard EHR benchmarks, demonstrates strong robustness to label noise, and exhibits superior cross institutional generalization compared to sequence based pretraining objectives. These results suggest that explicitly modeling the supervision process rather than treating labels as fixed targets provides a more appropriate inductive bias for learning robust and clinically meaningful representations from EHR data.

A reliable resume-job matching system helps a company find suitable candidates from a pool of resumes and helps a job seeker find relevant jobs from a list of job posts. While recent advances in embedding-based methods such as ConFit and ConFit v2 can efficiently retrieve candidates at scale, the lack of controllability and explainability limits their real-world adaptations. LLM-based re-rankers can address these limitations through reasoning, but existing training recipes are developed on short-document benchmarks and do not account for noise in real-world recruiting data. In this work, we first conduct a systematic analysis over the LLM re-ranker training pipeline for person-job fit, covering inference algorithm design, RL algorithm selection, data processing, and SFT distillation. We find that using multi-pass re-ranking, training with listwise RL objectives, removing noisy samples, and distilling from a stronger LLM before RL significantly improves re-ranking performance. We then aggregate these findings to train ConFit v3 with Qwen3-8B and Qwen3-32B on real-world person-job fit datasets, and find significant improvements over existing best person-job fit systems as well as strong LLMs such as GPT-5 and Claude Opus-4.5. We hope our findings provide useful insights for future research on adapting LLM-based re-rankers to person-job fit systems.

Providing non-conservative uncertainty quantification for function estimates derived from noisy observations remains a fundamental challenge in statistical machine learning, particularly for applications in safety-critical domains. In this work, we propose novel non-asymptotic probabilistic uniform error bounds for kernel-based regression. Compared to related bounds in the literature that are restricted to (conditionally) independent sub-Gaussian noise, our bounds allow to consider a broad class of non-Gaussian distributions, such as sub-Gaussian, bounded, sub-exponential, and variance/moment-bounded noise. Moreover, our results apply to correlated and uncorrelated noise. We compare our proposed error bounds with existing results in terms of the induced uncertainty region and their performance in safe control, demonstrating the tightness of the proposed bounds.

Trainable input embedding tables are a standard component of modern language models. We ask whether they are actually necessary at the input interface. For a vocabulary of size $V$, exact token identity requires only $K=\lceil \log_2 V\rceil$ bits. We replace the usual trainable $V\times d_{\text{model}}$ input embedding matrix with fixed minimal binary token codes and a zero-parameter lift to model width. In our main setting, $V=65{,}536$, so $K=16$, and tokens are represented by fixed 16-dimensional binary codes tiled to $d_{\text{model}}=1024$. We also evaluate a fully table-free variant in which codes are generated from token IDs on the fly and randomly recoded by an invertible affine transform over $\mathbb{F}_2^K$. Across matched 32-layer decoder-only models trained on approximately 17B tokens and evaluated over three independent training seeds, fixed minimal codes achieve comparable held-out validation perplexity to a standard learned-input baseline while removing 67.1M trainable input parameters. The fixed-code runs have a lower mean validation perplexity in our experiments, 2.36 versus 2.44, but the observed gap is within the measured seed-to-seed variation of 4.8\%; we therefore interpret the result as evidence that the trainable input table is not necessary, rather than as a statistically resolved superiority claim. The table-free affine-recoded variant remains close at 2.39 despite a slightly shorter training run. These results show that, in this regime, a trainable input embedding table is not necessary for useful language modeling. The output projection remains standard and trainable.

This article presents a novel approach to keyframe detection in ultrasound videos, with a particular focus on fetal brain imaging. The proposed model is a composite neural network architecture that combines a Convolutional Neural Network (CNN) with a Recurrent Neural Network (RNN). The CNN extracts spatial features from individual video frames, while the RNN captures temporal dependencies between consecutive frames within each video sequence. The proposed model may improve the efficiency and accuracy of fetal brain ultrasound analysis, thereby supporting earlier detection, diagnosis, and treatment planning for selected fetal brain conditions.

Discrete diffusion models generate structured sequences by progressively unmasking tokens, but enforcing global property constraints during generation remains an open challenge. We propose primal-dual guided decoding, an inference-time method that formulates constrained generation as a KL-regularised optimisation problem and solves it online via adaptive Lagrangian multipliers. At each denoising step, the method modifies token logits through an additive, constraint-dependent bias, with multipliers updated by mirror descent based on constraint violation. The bias arises as the optimal KL-regularised projection of the constraint, so the constrained distribution remains as close as possible to the model's unconstrained distribution while still satisfying the constraint. The method requires no retraining and no additional model evaluations beyond standard sampling, supports multiple simultaneous constraints, and provides formal bounds on constraint violation. We evaluate our approach on topical text generation, molecular design, and music playlist generation, showing that a single algorithm instantiated via domain-specific scoring functions improves constraint satisfaction while preserving relevant domain-specific quality metrics.

Landslide detection from satellite imagery has advanced through deep learning, yet most models rely on large, highly correlated spectral-topographic inputs whose contributions remain poorly understood. The question of which channels are actually necessary has received surprisingly little attention. This matters: redundant or correlated inputs obscure physical interpretability, inflate computational overhead, and can actively degrade model performance through the Hughes Phenomenon. We present a systematic, explainable channel-selection framework for the Landslide4Sense benchmark, combining Sentinel-2 multispectral and ALOS PALSAR terrain data with 16 engineered spectral and structural indices. Rather than relying on conventional single-band drop tests, which evaluate channels in isolation and miss interaction effects, we apply Sequential Forward Floating Selection (SFFS) to iteratively build and prune a candidate feature pool using a lightweight U-Net++ proxy model. Beyond identifying a compact 8-channel subset that matches or exceeds the segmentation F1 of configurations using up to 30 channels, we use the selection process itself to interrogate which spectral and topographic features landslide models genuinely rely on, and what this reveals about the physical cues driving their predictions. We argue that SFFS represents a principled feature selection approach to input design in Earth observation, in contrast to the prevailing practice of appending every available band and hoping the model learns what to ignore.

Large language models (LLMs) achieve remarkable generative performance, yet their output quality is dependent on the decoding strategy. While sampling-based methods (e.g., top-k, nucleus) and search-and-select based methods (e.g., beam search, best-of-n, majority voting) can improve upon greedy decoding, both approaches suffer from limitations: sampling generally commits to a single path, while search often expends excessive computation regardless of task complexity. To address these, we introduce Entropy-informed decoding (EDEN), a plug-and-play, model-agnostic decoding framework that adaptively allocates computation based on the model's own uncertainty, approximating higher-width beam search with fewer expansions. At each generation step, EDEN estimates the entropy of the output token distribution and adjusts the branching factor monotonically with the entropy, expanding more candidates in high-entropy regions and following a greedier path in low-entropy regions, improving token efficiency. Experiments across complex tasks, including mathematical reasoning, code generation, and scientific questions, demonstrate that EDEN consistently improves output quality over existing decoding strategies, achieving better accuracy-expansion trade-offs than fixed-width beam search. By treating next-token selection as a noisy maximisation problem, we prove that branching factors monotone in entropy are guaranteed to find better (i.e. more probable) continuations than any fixed branching factor within the same total expansion budget, and derive explicit regret rates characterising the benefit of the adaptive allocation.

Selective state space models (SSMs), such as Mamba, achieve strong per-token expressivity by making the time discretization step $\TildeΔ$ a learned function of the input. However, in doing so, $\TildeΔ$ ceases to represent a physical sampling interval, limiting its irregular time series modeling capability. Continuous-time SSMs, such as S5, preserve the physical meaning of $\TildeΔ$ and handle irregular timestamps natively ($\TildeΔ\equivΔ)$, but their dynamics remain linear time-invariant (LTI), limiting per-token expressivity. We propose \textbf{TIDES}, a selective SSM variant that reconciles selective and continuous architectures by moving input-dependence off the step size and onto the diagonal state matrix. As a result, $\TildeΔ$ retains its physical meaning, tied to the state discretization, allowing the model to handle irregular timestamps natively without sacrificing the per-token expressivity that makes selective SSMs effective. We show this on a novel \emph{Fading Flash} experimental benchmark, a compact controlled diagnostic for sequence models that jointly tests input-dependence and extrapolation to out-of-distribution $Δ$ values, and isolates the distinct failure modes of current state-of-the-art architectures that TIDES avoids by construction. On large-scale benchmarks, TIDES sets the new state-of-the-art average rank on UEA time-series classification and the Physiome-ODE regression benchmark. Code available at: https://github.com/TaylanSoydan/TIDES.

Large Language Models are increasingly used as zero-shot classifiers in complex reasoning tasks. However, standard constrained decoding suffers from a phenomenon we define as Renormalization Bias. When a model is restricted to a small set of target labels, the standard softmax operation discards the probability mass assigned to semantic synonyms in the original distribution. This loss of information, which we call the Silent Vote, results in artificial overconfidence and poor calibration. We propose Semantic Softmax, an inference-time layer that recovers this lost information by aggregating the scores of the semantic neighborhood surrounding each target label. We evaluate this approach on Qwen-3 and Phi-4-mini models using GoEmotions and Civil Comments datasets. Our results demonstrate consistent improvements across all evaluation metrics: Semantic Softmax substantially reduces Expected Calibration Error (ECE) and Brier Score, while simultaneously enhancing discriminative performance in terms of AUROC and Macro-F1. By accounting for linguistic nuances, our method provides a more calibrated and accurate alternative for zero-shot classification.

Modern large language models (LLMs) rely on system prompts to establish behavioral constraints and safety rules. Standard causal self-attention treats privileged instructions and untrusted user content with equal structural priority -- a mismatch that leaves models vulnerable to prompt injection and instruction erosion over extended contexts. We propose CALYREX (Cross-Attention LaYeR EXtended transformers), which utilizes cross-attention between input and system prompt to structurally isolate and anchor the rule. A placement ablation on a 1.5B backbone identifies insertion at the final eighth of layers as optimal, confirmed by mechanistic activation analysis showing behavioral constraints are naturally concentrated there. At 8B scale, controlling for training data, backbone, and parameter budget, CALYREX yields $+7.4\%$ on instruction-following (IFEval) and $+16.3\%$ on multi-turn instruction adherence, while reducing many-shot jailbreaking attack success rate by $13\%$. This advantage appears to widen with model scale, consistent with larger models more effectively utilizing the dedicated routing pathway.

A central challenge in reinforcement learning (RL) is to learn models that generalize beyond the tasks on which they are trained, a goal traditionally pursued through multi-task and meta RL. Recently, transformer architectures have emerged as a promising approach, enabling adaptation to new tasks via in-context learning without explicit parameter updates. From a functional perspective, a transformer can be viewed as a functional operator that maps a context to a task-specific function. It is thus fundamental to understand and design this operator to support stronger generalization in RL. In this work, we address this resulting question of generalization from a kernel-based perspective by establishing a connection between non-linear transformers and kernel-based temporal difference learning. By interpreting the transformer as performing regression in a Reproducing Kernel Hilbert Space (RKHS), we show that value functions from different domains can be represented using a shared set of weights, provided they lie within the same RKHS. Experiments on multiple MetaWorld domains support this interpretation, demonstrating convergence of the temporal-difference objective.

Existing accounts of grokking explain the phenomena in terms of mechanistic frameworks such as circuit efficiency or lazy-to-rich transitions. However, despite a known dependence between grokking and model size, how model capacity shapes grokking remains an open question. We give an information-theoretic account of this relationship on the task of modular arithmetic, showing that grokking does not immediately occur when a model becomes large enough to memorise the training set, but rather emerges as the outcome of a competition between two measurable timescales: a memorisation speed $T_{\text{mem}}(P)$ and a generalisation speed $T_{\text{gen}}(P)$, both of which are functions of model parameter count $P$. Adapting the information capacity framework of Morris et al. (2025), we estimate $T_{\text{mem}}(P)$ on random-label data of equivalent complexity and $T_{\text{gen}}(P)$ on the modular task itself, and show that grokking emerges close to the parameter scale where these timescales intersect. The framework also suggests an empirical model for predicting memorisation speed given model capacity and dataset complexity, recovering the previously reported empirical observation that larger models memorise faster. Overall, we motivate the formalisation of different learning timescales as important abstractions to study when explaining how model capacity shapes grokking on algorithmic tasks.

Obtaining an accurate short-term forecasting for heat demand is an essential part of operating district heating networks cost-efficient and reliable. Heat consumption time series at the building level are highly dependent on exogenous variables such as outdoor temperature and individual usage patterns, making forecasting in this context a challenging task. Thus, this paper benchmarks novel Transformer-based and xLSTM architectures for short-term heat-demand forecasting. Using hourly data from 25 German buildings (2017-2025), we compare three-hour and 24-hour forecasting horizons relevant for intraday control and day-ahead scheduling. We establish a multi-building benchmark that tests whether models trained on pooled, heterogeneous building data are able to generalize across diverse building stock. The results show that the xLSTM achieves the lowest RMSE (19.88 kWh for three-hour, 21.47 kWh for 24-hour forecasts), while the Temporal Fusion Transformer attains the best MAE (9.16 kWh for three-hour forecasts). As xLSTMs and Transformers require long training times and have a huge number of trainable parameters, their sustainability remains questionable. Therefore, this paper further investigates the trade-off between predictive accuracy and computational resource demand of the evaluated forecasting models. The findings indicate that also low-parameter models like a traditional fully-connected network achieve good predictive results, highlighting that marginal accuracy gains of the novel prediction models come at substantial resource expense for this use case.

Large-scale 3D vision-language models (VLMs) like LLaVA-3D offer strong spatial reasoning but are difficult to deploy due to high computational costs. We propose a knowledge distillation framework that transfers spatial reasoning from a 7B teacher to a 2.29B student model. Our approach achieves 8.7x lower inference latency and a 3x reduction in model size while retaining 54-72% of the teacher's performance. The framework utilizes VGGT as the vision encoder and a multi-task distillation pipeline with uncertainty-aware loss weighting. To improve reasoning without chain-of-thought (CoT) data, we introduce "Hidden CoT": learnable latent tokens that serve as an internal scratchpad before answer generation. This is the first use of latent scratchpad reasoning in distilled 3D VLMs. The student model jointly performs spatial description, depth estimation, and object detection. Experiments on ScanNet and 3D-FRONT show strong spatial understanding, reaching 68-72% accuracy on proximity and contact tasks. Our framework enables efficient 3D scene QA on resource-constrained platforms.

Medicine is rife with high-stakes uncertainty. Doctors routinely make clinical judgments and decisions that juggle many fundamental unknowns, like predictions about what might be causing a patients' symptoms or decisions about what treatment to try next. Despite increasing interest in developing AI systems that aid or even replace doctors in clinical settings, current systems struggle with calibrated reasoning under uncertainty, and are often deeply opaque about their reasoning. We propose a framework for AI systems that can make practically useful but formally transparent clinical predictions under uncertainty. Given a clinical situation, our framework (MedMSA) uses language models to retrieve relevant prior knowledge, but constructs a formal probabilistic model to support calibrated and verifiable inferences under uncertainty. We show how an initial proof-of-concept of this framework can be used for differential diagnosis, producing an uncertainty-weighted list of potential diagnoses that could explain a patients' symptoms, and discuss future applications and directions for applying this framework more generally for safe clinical collaborations.

We present Metal-Sci, a 10-task benchmark of scientific Apple Silicon Metal compute kernels spanning six optimization regimes (stencils, all-pairs in $n$-body problems, multi-field Boltzmann, neighbor-list molecular dynamics, multi-kernel PDE, FFT). Each task ships a CPU reference, a roofline-anchored fitness function, and a held-out generalization size. We pair the benchmark with a lightweight harness for automatic kernel search that runtime-compiles each candidate, scores it against the roofline across multiple sizes, and feeds structured compile and per-size correctness diagnostics back to a frozen LLM driving a $(1{+}1)$ evolutionary loop. We report matched single-model sweeps of Claude Opus 4.7, Gemini 3.1 Pro, and GPT 5.5 on M1 Pro: in-distribution self-speedups span $1.00\times$ to $10.7\times$. Beyond raw speedup, our central methodological claim is structural: the held-out gate scoring function $Φ_\mathcal{T}$ (evaluated once at end-of-run on a configuration the agent never sees during search) functions as a cheap mechanical oversight primitive on this automatic search loop, catching e.g. an Opus template <uint D> HMC win that returns wrong samples at unseen dimensions, and a GPT FFT3D best that wins in-distribution at $2.95\times$ speedup but collapses to $0.23\times$ on a $256^3$ held-out cube, a silent regression that the in-distribution score alone cannot see. Code at https://github.com/vicgalle/metal-sci-kernels

Training neural networks to satisfy universal constraints over continuous domains poses unique challenges. Common examples include Lyapunov Neural Networks (Lyapunov NNs) and Physics-Informed Neural Networks (PINNs), where analytical solutions are generally either unavailable or overly restrictive. Sample-based methods are therefore commonly used to enforce these constraints, and the choice of samples has a substantial impact on convergence speed, stability, and solution quality. Most existing methods rely on fixed heuristics or handcrafted rules, and are suboptimal in practice. In this paper, we aim to improve upon them by learning, from data and experience, how to dynamically and iteratively adjust the samples in response to the model's evolving learning performance. Trained by reinforcement learning, the learned policy improves empirical constraint satisfaction on test problems while significantly improving efficiency. We validate the approach on both Lyapunov NNs and PINNs, and demonstrate its broader applicability to domains where adaptive input selection is essential for effective training.

Understanding human mental states from natural behavior is crucial for intelligent systems in the real world. However, most current research focuses on predicting isolated mental state labels, lacking structured annotations of complex interpersonal interactions. To support structured analysis, we introduce MOTOR-Bench, a carefully-designed benchmark with a real-world dataset MOTOR-dataset, containing 1,440 multimodal video clips in collaborative learning scenarios, reflecting key real-world data challenges including natural class imbalance, visual noise, and domain-specific language. Each sample is labeled by educational experts based on self-regulated learning theory. We further evaluate several state-of-the-art multimodal large language models and multi-agent systems in a zero-shot setting on our MOTOR-Bench. However, their performance on this task remains limited, suggesting that existing methods still struggle with structured reasoning from observable behavior to deeper mental states. To address this challenge, we propose a reasoning multi-agent framework, named MOTOR-MAS. It coordinates multiple agents through a structured agent coordination mechanism to infer explicit behaviors, internal cognitions, and psychological emotions. Experimental results show that our MOTOR-MAS outperforms the best single-model benchmark by 15.93 points in Macro-F1 scores for the three labels of behavior, cognition, and emotion, and outperforms the general multi-agent benchmark by 10.2 points in internal cognition prediction.

Existing latent world models for autonomous driving have opened a promising path toward future-aware driving intelligence. However, they typically treat future latent states as prediction targets or auxiliary signals, rather than directly conditioning trajectory planning. This can entangle current and future features in latent space. In this work, we propose DriveFuture, a future-aware latent world modeling framework for autonomous driving that explicitly learns planning-oriented foresight by conditioning the current latent state modeling process on future world states. Specifically, during training, the model first predicts future latent world states from the current latent state and ego action, and then refines the prediction against the ground-truth future latent state via cross-attention. The resulting future-aware latent serves as an explicit condition for a diffusion-based trajectory planner. During inference, DriveFuture conditions on the predicted future latent state instead of the ground-truth future state. DriveFuture achieves SOTA performance on the public NAVSIM benchmarks, reaching \textbf{55.5} EPDMS on NAVSIM-v2 {\textcolor{blue}{\textit{navhard}}}, \textbf{89.9} EPDMS on NAVSIM-v2 {\textcolor{blue}{\textit{navtest}}}, and \textbf{90.7} PDMS on NAVSIM-v1 {\textcolor{blue}{\textit{navtest}}}, respectively. These results suggest that the key to latent world modeling lies not merely in simulating future states, but more importantly in conditioning current decision-making on future states. Notably, as of April 2026, DriveFuture ranks \textbf{1st} on the \href{https://huggingface.co/spaces/AGC2025/e2e-driving-navhard}{NAVSIM-v2 {\textcolor{blue}{\textit{navhard}}}} leaderboard and achieves SOTA performance on \href{https://huggingface.co/spaces/AGC2024-P/e2e-driving-navtest}{NAVSIM-v1 {\textcolor{blue}{\textit{navtest}}}}.

As data-science agents shift from co-pilots to auto-pilots, silent misframing becomes a critical failure mode. Agents quietly commit to plausible but unintended task framings, producing clean, executable artifacts that hide their incorrect assessment of the task. Existing benchmarks score whether the pipeline runs, ignoring whether the agent recognized the task was underspecified. We introduce Ambig-DS, two diagnostic suites: one for prediction-target ambiguity (Ambig-DS-Target, 51 tasks built on DSBench, a tabular modeling benchmark) and one for evaluation-objective ambiguity (Ambig-DS-Objective, 61 tasks built on MLE-bench, a Kaggle-style ML competition benchmark), constructed so that scoring uses each source benchmark's original evaluator. For every task we pair the original, fully specified version with an ambiguous variant produced by controlled edits; a human-and-LLM verification pipeline confirms each variant admits multiple plausible interpretations with decision-relevant consequences. The suites are analyzed independently and ambiguity lowers performance in both. Across five agents spanning efficient to frontier-class models, we find in our controlled diagnostic setting: (i) failures are silent commitments: wrong-target submissions on Target, wrong-metric or non-committal baseline submissions on Objective, rather than execution errors; (ii) allowing the agent to ask one clarifying question recovers much of the loss under idealized conditions, suggesting missing framing information drives a substantial part of the observed degradation; but (iii) agents cannot reliably tell when to use it: permissive prompts induce over-asking on clear tasks, while conservative prompts induce silent defaulting on ambiguous ones. Recognizing target and objective underspecification, not pipeline execution, is the bottleneck missing from standard DS-agent evaluations.

Discovering governing equations from observational data remains a fundamental challenge in scientific modeling, particularly when the underlying mathematical structure is unknown. Traditional sparse identification methods like SINDy excel at discovering parsimonious models but require researchers to specify candidate basis functions a priori, a limitation that often leads to model failure when critical terms are omitted or when systems exhibit unconventional dynamics. Purely symbolic regression approaches offer unlimited flexibility but struggle with noise sensitivity and frequently produce overly complex, unstable equations. We present AutoSINDy, a hybrid Discovery-then-Solve framework that combines the exploratory power of symbolic regression with the robust sparsity-promoting capabilities of SINDy. Our method operates in three stages: (1) PySR-based symbolic regression discovers candidate functional forms from bootstrapped data chunks; (2) a curation pipeline decomposes, expands, and filters these expressions using collinearity analysis to construct a minimal yet comprehensive library; and (3) SINDy identifies sparse governing equations from this custom-tailored library. Extensive experiments across canonical nonlinear systems demonstrate that AutoSINDy consistently recovers ground-truth equations even under high observational noise, achieving a ground-truth recovery rate of 92.8% across all trials. Compared with standard SINDy using enriched libraries and standalone symbolic regression, AutoSINDy achieves higher predictive accuracy, superior generalization to unseen trajectories, and substantially lower symbolic complexity.

Yes. We find that large multimodal models develop mental imagery when solving spatial puzzles, and they do imagine sheep when solving sheep puzzles. We fine-tune a Qwen3.5 VLM to solve twelve diverse visual reasoning tasks -- including tangram, jigsaw, sokoban, 3D mental rotation, and rush hour -- that require understanding geometry, spatial relationships, and the consequences of actions. By supervising the model to predict the open-loop sequence of actions to solve a puzzle from an initial state, we show that the model's activations after each action encode meaningful visual information about the intermediate state. This finding suggests that an imperfect visual world model begins to form as a byproduct of learning to select correct actions, in the absence of any explicit visual supervision. Building on this observation, we propose two ways to sharpen and use the mental images formed by the model. We find that integrating as few as sixteen visual tokens per step into the chain of thought improves the average solve rate from 83% to 89%, with particularly strong gains on reasoning-heavy tasks such as jigsaw and 3D mental rotation.

Population pharmacokinetic/pharmacodynamic (PK/PD) modeling traditionally relies on classical ordinary differential equations to simulate drug dynamics. In this work, we reformulate a compartmental PK/PD model as an open quantum system and implement it using quantum circuits developed in PennyLane. Four pharmacological compartments (central, peripheral, effect-site, and response) are encoded using twelve qubits, with inter-compartmental transitions represented through controlled quantum operations that emulate stochastic dynamics. The framework is evaluated on Phase 1 clinical data using a quantum-enhanced stochastic approximation expectation-maximization (SAEM) approach. Compared with the classical implementation, the quantum model achieves substantially improved log-likelihood values, indicating stronger statistical fit while preserving identical parameter estimates, thereby validating numerical consistency and model interpretability. The quantum-based optimization converges faster in terms of iterations, although total runtime is increased due to current simulation overhead. The study demonstrates stable large-scale simulation performance and establishes a hybrid quantum-classical approach that maintains biological fidelity while improving statistical modeling capacity. The dataset and problem statement originate from the Quantum Innovation Challenge 2025, and additional details are provided via the associated link.

Feedforward 3D Gaussian Splatting (3DGS) often struggles in trajectory-based sparse-view driving scenes. Existing Gaussian repair methods mainly target optimization-based 3DGS, while diffusion-based repair is typically restricted to iterative refinement near observed viewpoints, leaving feedforward 3DGS repair underexplored. We propose ConFixGS, a plug-and-play method that learns to fix feedforward 3DGS with confidence-aware diffusion priors. Starting from a pretrained feedforward model, ConFixGS generates diffusion-enhanced local pseudo-targets and validates them through reprojection-based cross-checking against support views. The resulting dense confidence maps guide refinement, enhancing reliable details while suppressing hallucinated or inconsistent evidence. On Waymo, nuScenes, and KITTI, ConFixGS improves challenging novel view synthesis, with PSNR gains of up to 3.68 dB and FID reduced by nearly half. Our results highlight confidence-aware fusion of generative priors and support-view consistency as a key principle for robust feedforward 3D driving scene reconstruction.

Remote Sensing (RS) single-image super-resolution aims to reconstruct high-resolution imagery from low-resolution observations while preserving fine spatial structures. Recent Swin Transformer-based models, including Swin2SR, provide strong spatial context modeling throughshifted-window self-attention, but their feed-forward networks remain generic channel-mixing modules and do not separate low-frequency structural content from high-frequency residual detail. To address this limitation, we propose SFG-SwinSR, a Spatial-Frequency Gated Swin Transformer for single-image super-resolution in remote sensing. SFG-SwinSR modifies the original Swin2SR attention block by replacing each transformer block's standard feed-forward network with a lightweight Spatial-Frequency Gated Feed-Forward Network (SFG-FFN). The module estimates low-frequency content via a depthwise-blur branch, extracts high-frequency residuals by subtraction, refines them with a lightweight spatial branch, and adaptively injects detail through a bottleneck gate. Experiments on SpaceNet and SEN2VENμS show that SFG-SwinSR improves reconstruction quality under the evaluated settings. On SpaceNet, it achieves 45.19 dB PSNR and 0.9852 SSIM, indicating effective enhancement of high-frequency details. This demonstrates that spatial-frequency transformation within the transformer feed-forward network improves detail reconstruction in RS super-resolution.

The core challenge in unsupervised anomaly detection is identifying abnormal patterns without prior knowledge of their characteristics. While existing methods have addressed aspects of this problem, they often struggle to learn a robust representation of the normal data distribution that is distinct from anomalous patterns. In this paper, we present a novel framework, Unified Unsupervised Anomaly Detection ($\text{U}^2\text{AD}$), that comprehensively addresses anomaly detection in multivariate time series. Our approach learns the underlying data distribution of normal samples by utilizing score-based generative modeling. We introduce a novel time-dependent score network and a unified training objective that together delineate the manifold of normal data while considering both local and global temporal contexts. Reconstruction is then performed via a deterministic sampling process using an ordinary differential equation solver. Our extensive experimental evaluations demonstrate that $\text{U}^2\text{AD}$ not only outperforms current state-of-the-art methods in detection accuracy but also identifies anomalies at significantly earlier stages of their occurrence.

Autoregressive (AR) video diffusion models adopt a streaming generation framework, enabling long-horizon video generation with real-time responsiveness, as exemplified by the Self Forcing training paradigm. However, existing AR video diffusion models still suffer from significant attention complexity and severe memory overhead due to the redundant key-value (KV) caches across historical frames, which limits scalability. In this paper, we tackle this challenge by introducing KV cache compression into autoregressive video diffusion. We observe that attention heads in mainstream AR diffusion models exhibit markedly distinct attention patterns and functional roles that remain stable across samples and denoising steps. Building on our empirical study of head-wise functional specialization, we divide the attention heads into two categories: static heads, which focus on transitions across autoregressive chunks and intra-frame fidelity, and dynamic heads, which govern inter-frame motion and consistency. We then propose Forcing-KV, a hybrid KV cache compression strategy that performs structured static pruning for static heads and dynamic pruning based on segment-wise similarity for dynamic heads. While maintaining output quality, our method achieves a generation speed of over 29 frames per second on a single NVIDIA H200 GPU along with 30% cache memory reduction, delivering up to 1.35x and 1.50x speedups on LongLive and Self Forcing at 480P resolution, and further scaling to 2.82x speedup at 1080P resolution. Code and demo videos are provided at https://zju-jiyicheng.github.io/Forcing-KV-Page.

Medical vision-language models (VLMs) and AI agents have made significant progress in learning to analyze and reason about clinical images. However, existing medical visual question answering (VQA) benchmarks collapse model capabilities into a single accuracy score, obscuring where and why models fail. We propose DeepTumorVQA, a hierarchical benchmark that follows the multi-stage evidence chain in tumor diagnosis and decomposes 3D CT reasoning into four stages: recognition, measurement, visual reasoning, and medical reasoning. Higher-level questions remain independently scorable, while their ground-truth evidence chains are defined over lower-level primitives. The benchmark contains 476K questions across 42 clinical subtypes on 9,262 3D CT volumes. In addition to a direct reasoning mode for VLMs, DeepTumorVQA provides tool-interaction environments for agent evaluation, where a model can call external tools, including segmentation models, measurement programs, and medical knowledge modules, before answering the question. Evaluating over 30 model configurations, we find that reliable quantitative measurement is the primary bottleneck, making later-stage visual and medical reasoning harder for VLMs, while tool augmentation substantially mitigates this issue. When tools are available, leveraging medical knowledge and tools to reason about medical images becomes a new challenge. We further show that ground-truth step-by-step tool-use traces from DeepTumorVQA can supervise agents and reduce tool-use and reasoning failures. This stage-wise progression from recognition to measurement to visual and medical reasoning provides a concrete roadmap for future medical VLM and AI agent studies. All data and code are released at https://github.com/Schuture/DeepTumorVQA.