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2604.14906 2026-04-17 physics.bio-ph cs.LG

Unraveling the Mechanism of Drug Binding to SARS-CoV-2 RNA Pseudoknot with Thermodynamics-Driven Machine Learning

Mariia Ivonina, Jakub Rydzewski

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英文摘要

The SARS-CoV-2 RNA pseudoknot is a promising target for antiviral intervention, as it regulates the efficiency of $-$1 programmed ribosomal frameshifting ($-$1 PRF), a mechanism that is essential for viral protein synthesis. The pseudoknot represents a viral RNA sequence composed of helical stems that adopts two long-lived topologies, threaded and unthreaded. Ligand-induced distortion of this fold is thought to underlie the susceptibility of $-$1 PRF to small-molecule inhibitors. Resolving these distortions from unbiased molecular dynamics (MD) requires collective variables (CVs) that isolate the slowest dynamic modes of the RNA--ligand system from the high-frequency fluctuations. Here, we use spectral map (SM), a thermodynamics-driven machine-learning method, to learn such CVs directly from MD trajectories of the SARS-CoV-2 RNA pseudoknot in complex with the $-$1 PRF inhibitor merafloxacin and two related analogs. We examine both threaded and unthreaded pseudoknot topologies and consider the neutral and ionized ligand forms relevant at physiological pH. Free-energy landscapes show that ligand-induced destabilization is topology-selective: merafloxacin and its analogs destabilize the S2 stem in the threaded pseudoknot, whereas in the unthreaded pseudoknot, destabilization shifts to the S1 and S3 stems. We find that the zwitterionic form of merafloxacin uniquely imposes slow dynamics on the otherwise featureless unthreaded pseudoknot. Furthermore, the neutral and zwitterionic forms of merafloxacin differ qualitatively in their mechanisms within the same RNA topology. Overall, these results clarify how pseudoknot topology, ligand type, and protonation state shape the slow conformational dynamics of viral RNA and establish physiological protonation as an essential factor for modeling RNA-targeted drug action.

2604.14878 2026-04-17 cs.IR cs.AI

GenRec: A Preference-Oriented Generative Framework for Large-Scale Recommendation

Yanyan Zou, Junbo Qi, Lunsong Huang, Yu Li, Kewei Xu, Jiabao Gao, Binglei Zhao, Xuanhua Yang, Sulong Xu, Shengjie Li

Comments SIGIR 2026 Camera-Ready version

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英文摘要

Generative Retrieval (GR) offers a promising paradigm for recommendation through next-token prediction (NTP). However, scaling it to large-scale industrial systems introduces three challenges: (i) within a single request, the identical model inputs may produce inconsistent outputs due to the pagination request mechanism; (ii) the prohibitive cost of encoding long user behavior sequences with multi-token item representations based on semantic IDs, and (iii) aligning the generative policy with nuanced user preference signals. We present GenRec, a preference-oriented generative framework deployed on the JD App that addresses above challenges within a single decoder-only architecture. For training objective, we propose Page-wise NTP task, which supervises over an entire interaction page rather than each interacted item individually, providing denser gradient signal and resolving the one-to-many ambiguity of point-wise training. On the prefilling side, an asymmetric linear Token Merger compresses multi-token Semantic IDs in the prompt while preserving full-resolution decoding, reducing input length by ~2X with negligible accuracy loss. To further align outputs with user satisfaction, we introduce GRPO-SR, a reinforcement learning method that pairs Group Relative Policy Optimization with NLL regularization for training stability, and employs Hybrid Rewards combining a dense reward model with a relevance gate to mitigate reward hacking. In month-long online A/B tests serving production traffic, GenRec achieves 9.5% improvement in click count and 8.7% in transaction count over the existing pipeline.

2604.14876 2026-04-17 cs.IT cs.LG math.IT

Regret Tail Characterization of Optimal Bandit Algorithms with Generic Rewards

Subhodip Panda, Shubhada Agrawal

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Journal ref
2026 IEEE International Symposium on Information Theory (ISIT 2026)
英文摘要

We study the tail behavior of regret in stochastic multi-armed bandits for algorithms that are asymptotically optimal in expectation. While minimizing expected regret is the classical objective, recent work shows that even such algorithms can exhibit heavy regret tails, incurring large regret with non-negligible probability. Existing sharp characterizations of regret tails are largely restricted to parametric settings, such as single-parameter exponential families. In this work, we extend the $\KLinf$-UCB algorithm of to a broad nonparametric class of reward distributions satisfying mild assumptions, and establish its asymptotic optimality in expectation. We then analyze the tail behavior of its regret and derive a novel upper bound on the regret tail probability. As special cases, our results recover regret-tail guarantees for both bounded-support and heavy-tailed (moment-bounded) bandit models. Moreover, for the special case of finitely-supported reward distributions, our upper bound matches the known lower bound exactly. Our results thus provide a unified and tight characterization of regret tails for asymptotically optimal KL-based UCB algorithms, going beyond parametric models.

2604.14867 2026-04-17 cs.SE cs.AI

Vibe-Coding: Feedback-Based Automated Verification with no Human Code Inspection, a Feasibility Study

Michal Töpfer, František Plášil, Tomáš Bureš, Petr Hnětynka

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英文摘要

Vibe coding inherently assumes iterative refinement of LLM-generated code through feedback loops. While effective for conventional software tasks, its reliability in runtime-adaptive systems is unclear -- especially when generated code is not manually inspected. This paper studies feedback-based automated verification of LLM-generated adaptation managers in Collective Adaptive Systems (CAS). We focus on the key challenges of verification in the loop: how to detect failures of generated code at runtime and how to report them precisely enough for an LLM to fix them. We combine the adaptation loop with a vibe-coding feedback loop where correctness is checked against (i) generic architectural constraints and (ii) functional constraints formalized in Functional Constraints Logic (FCL), a novel first-order temporal logic over potentially finite traces. Conducting the Dragon Hunt CAS case study, we show that fine-grained constraint violations provide actionable feedback that typically yields a valid adaptation manager within a few iterations, while simple coarse metric-based feedback often stalls. Our findings suggest that feedback precision is the dominant factor for reliable vibe coding in systems designed by domain experts with no programming skills, thereby obviating the need for human code inspection.

2604.14860 2026-04-17 stat.ML cs.LG

Best of both worlds: Stochastic & adversarial best-arm identification

Yasin Abbasi-Yadkori, Peter L. Bartlett, Victor Gabillon, Alan Malek, Michal Valko

Comments Published in Conference on Learning Theory (COLT 2018)

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英文摘要

We study bandit best-arm identification with arbitrary and potentially adversarial rewards. A simple random uniform learner obtains the optimal rate of error in the adversarial scenario. However, this type of strategy is suboptimal when the rewards are sampled stochastically. Therefore, we ask: Can we design a learner that performs optimally in both the stochastic and adversarial problems while not being aware of the nature of the rewards? First, we show that designing such a learner is impossible in general. In particular, to be robust to adversarial rewards, we can only guarantee optimal rates of error on a subset of the stochastic problems. We give a lower bound that characterizes the optimal rate in stochastic problems if the strategy is constrained to be robust to adversarial rewards. Finally, we design a simple parameter-free algorithm and show that its probability of error matches (up to log factors) the lower bound in stochastic problems, and it is also robust to adversarial ones.

2604.14825 2026-04-17 cs.PL cs.LG

Nautilus: An Auto-Scheduling Tensor Compiler for Efficient Tiled GPU Kernels

Yifan Zhao, Yuchen Yang, Matei Budiu, Sasa Misailovic

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英文摘要

We present Nautilus, a novel tensor compiler that moves toward fully automated math-to-kernel optimization. Nautilus compiles a high-level algebraic specification of tensor operators into efficient tiled GPU kernels. Nautilus's successive lowering design allows high-level optimizations, expression rewrites, and tile optimizations to be jointly applied in a single end-to-end system. Nautilus presents a novel auto-scheduler that discovers sequences of high-level optimizations, while preserving the regular program structure needed by tile optimizers. Nautilus's auto-scheduler captures complex interactions and trade-offs in the high-level optimizations, including aggressive global transformations like advanced reduction fusion. Nautilus is the first end-to-end tensor compiler capable of starting from a math-like description of attention and automatically discovering FlashAttention-3-like kernels, offloading the entire burden of optimization from the programmer to the compiler. Across five transformer-based models and 150 evaluation configurations on NVIDIA GH200 and RTX 5090 GPUs, Nautilus achieves up to 23% higher throughput than state-of-the-art compilers on GH200 and up to 42% on RTX 5090, while matching or exceeding manually written cuDNN kernels on many long-sequence configurations.

2604.14810 2026-04-17 stat.ML cs.LG stat.CO

Scalable Model-Based Clustering with Sequential Monte Carlo

Connie Trojan, Pavel Myshkov, Paul Fearnhead, James Hensman, Tom Minka, Christopher Nemeth

Comments Accepted at AISTATS 2026. 31 pages, 20 figures

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英文摘要

In online clustering problems, there is often a large amount of uncertainty over possible cluster assignments that cannot be resolved until more data are observed. This difficulty is compounded when clusters follow complex distributions, as is the case with text data. Sequential Monte Carlo (SMC) methods give a natural way of representing and updating this uncertainty over time, but have prohibitive memory requirements for large-scale problems. We propose a novel SMC algorithm that decomposes clustering problems into approximately independent subproblems, allowing a more compact representation of the algorithm state. Our approach is motivated by the knowledge base construction problem, and we show that our method is able to accurately and efficiently solve clustering problems in this setting and others where traditional SMC struggles.

2604.14809 2026-04-17 stat.ML cs.LG stat.AP

Expert-Guided Class-Conditional Goodness-of-Fit Scores for Interpretable Classification with Informative Missingness: An Application to Seismic Monitoring

Shahar Cohen, David M. Steinberg, Yael Radzyner, Yochai Ben Horin

Comments 50 pages, 8 figures

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英文摘要

We study a classification problem with three key challenges: pervasive informative missingness, the integration of partial prior expert knowledge into the learning process, and the need for interpretable decision rules. We propose a framework that encodes prior knowledge through an expert-guided class-conditional model for one or more classes, and use this model to construct a small set of interpretable goodness-of-fit features. The features quantify how well the observed data agree with the expert model, isolating the contributions of different aspects of the data, including both observed and missing components. These features are combined with a few transparent auxiliary summaries in a simple discriminative classifier, resulting in a decision rule that is easy to inspect and justify. We develop and apply the framework in the context of seismic monitoring used to assess compliance with the Comprehensive Nuclear-Test-Ban Treaty. We show that the method has strong potential as a transparent screening tool, reducing workload for expert analysts. A simulation designed to isolate the contribution of the proposed framework shows that this interpretable expert-guided method can even outperform strong standard machine-learning classifiers, particularly when training samples are small.

2604.14800 2026-04-17 eess.IV cs.CV physics.med-ph

Generative Modeling of Complex-Valued Brain MRI Data

Marco Schlimbach, Moritz Rempe, Jessica Mnischek, Lukas T. Rotkopf, Jens Weingarten, Jens Kleesiek, Kevin Kröninger

Comments 16 pages, 8 figures

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英文摘要

Objective. Standard Magnetic Resonance Imaging (MRI) reconstruction pipelines discard phase information captured during acquisition, despite evidence that it encodes tissue properties relevant to tumor diagnosis. Current machine learning approaches inherit this limitation by operating exclusively on reconstructed magnitude images. The aim of this study is to build a generative framework which is capable of jointly modeling magnitude and phase information of complex-valued MRI scans. Approach. The proposed generative framework combines a conditional variational autoencoder, which compresses complex-valued MRI scans into compact latent representations while preserving phase coherence, with a flow-matching-based generative model. Synthetic sample quality is assessed via a real-versus-synthetic classifier and by training downstream classifiers on synthetic data for abnormal tissue detection. Main results. The autoencoder preserves phase coherence above 0.997. Real-versus-synthetic classification yields low AUROC values between 0.50 and 0.66 across all acquisition sequences, indicating generated samples are nearly indistinguishable from real data. In downstream normal-versus-abnormal classification, classifiers trained entirely on synthetic data achieve an AUROC of 0.880, surpassing the real-data baseline of 0.842 on a publicly available dataset (fastMRI). This advantage persists on an independent external test set from a different institution with biopsy-confirmed labels. Significance. The proposed framework demonstrates the feasibility of jointly modeling magnitude and phase information for normal and abnormal complex-valued brain MRI data. Beyond synthetic data generation, it establishes a foundation for the usage of complete brain MRI information in future diagnostic applications and enables systematic investigation of how magnitude and phase jointly encode pathology-specific features.

2604.14796 2026-04-17 q-bio.BM cs.LG

PUFFIN: Protein Unit Discovery with Functional Supervision

Gökçe Uludoğan, Buse Giledereli, Elif Ozkirimli, Arzucan Özgür

Comments 21 pages, 9 figures, to appear in ISMB 2026 proceedings

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英文摘要

Proteins carry out biological functions through the coordinated action of groups of residues organized into structural arrangements. These arrangements, which we refer to as protein units, exist at an intermediate scale, being larger than individual residues yet smaller than entire proteins. A deeper understanding of protein function can be achieved by identifying these units and their associations with function. However, existing approaches either focus on residue-level signals, rely on curated annotations, or segment protein structures without incorporating functional information, thereby limiting interpretable analysis of structure-function relationships. We introduce PUFFIN, a data-driven framework for discovering protein units by jointly learning structural partitioning and functional supervision. PUFFIN represents proteins as residue-level structure graphs and applies a graph neural network with a structure-aware pooling mechanism that partitions each protein into multi-residue units, with functional supervision that shapes the partition. We show that the learned units are structurally coherent, exhibit organized associations with molecular function, and show meaningful correspondence with curated InterPro annotations. Together, these results demonstrate that PUFFIN provides an interpretable framework for analyzing structure-function relationships using learned protein units and their statistical function associations. We made our source code available at https://github.com/boun-tabi-lifelu/puffin.

2604.14787 2026-04-17 eess.SY cs.LG cs.NI cs.SY

Towards Trustworthy 6G Network Digital Twins: A Framework for Validating Counterfactual What-If Analysis in Edge Computing Resources

Julian Jimenez Agudelo, Paola Soto, Ayat Zaki-Hindi, Jean-Sébastien Sottet, Sébastien Faye, Nina Slamnik-Kriještorac, Johann Marquez-Barja, Miguel Camelo Botero

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英文摘要

Network Digital Twins (NDTs) enable safe what-if analysis for 6G cloud-edge infrastructures, but adoption is often limited by fragmented workflows from telemetry to validation. We present a data-driven NDT framework that extends 6G-TWIN with a scalable pipeline for cloud-edge telemetry aggregation and semantic alignment into unified data models. Our contributions include: (i) scalable cloud-edge telemetry collection, (ii) regime-aware feature engineering capturing the network's scaling behavior, and (iii) a validation methodology based on Sign Agreement and Directional Sensitivity. Evaluated on a Kubernetes-managed cluster, the framework extrapolates performance to unseen high-load regimes. Results show both Deep Neural Network (DNN) and XGBoost achieve high regression accuracy (R2 > 0.99), while the XGBoost model delivers superior directional reliability (Sa > 0.90), making the NDT a trustworthy tool for proactive resource scaling in out-of-distribution scenarios.

2604.14766 2026-04-17 eess.SP cs.AI

Temporal Cross-Modal Knowledge-Distillation-Based Transfer-Learning for Gas Turbine Vibration Fault Detection

Ali Bagheri Nejad, Mahdi Aliyari-Shoorehdeli, Abolfazl Hasanzadeh

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英文摘要

Preventing machine failure is inherently superior to reactive remediation, particularly for critical assets like gas turbines, where early fault detection (FD) is a cornerstone of industrial sustainability. However, modern deep learning-based FD models often face a significant trade-off between architectural complexity and real-time operational constraints, often hindered by a lack of temporal context within restricted vibration signal windows. To address these challenges, this study proposes a Temporal Cross-Modal Knowledge-Distillation Transfer-Learning (TCMKDTL) framework. The framework employs a "privileged" teacher model trained on expansive temporal windows incorporating both past and future signal context to distill latent feature-based knowledge into a compact student model. To mitigate issues of data scarcity and domain shift, the framework leverages robust pre-training on benchmark datasets (such as CWRU) followed by adaptation to target industrial data. Extensive evaluation using experimental and industrial gas turbine (MGT-40) datasets demonstrates that TCMKDTL achieves superior feature separability and diagnostic accuracy compared to conventional pre-trained architectures. Ultimately, this approach enables high-performance, unsupervised anomaly detection suitable for deployment on resource-constrained industrial hardware.

2604.14751 2026-04-17 cs.IT cs.DC cs.LG eess.SP math.IT

Exploiting Correlations in Federated Learning: Opportunities and Practical Limitations

Adrian Edin, Michel Kieffer, Mikael Johansson, Zheng Chen

Comments 14 pages, 7 figures, submitted for possible publication

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英文摘要

The communication bottleneck in federated learning (FL) has spurred extensive research into techniques to reduce the volume of data exchanged between client devices and the central parameter server. In this paper, we systematically classify gradient and model compression schemes into three categories based on the type of correlations they exploit: structural, temporal, and spatial. We examine the sources of such correlations, propose quantitative metrics for measuring their magnitude, and reinterpret existing compression methods through this unified correlation-based framework. Our experimental studies demonstrate that the degrees of structural, temporal, and spatial correlations vary significantly depending on task complexity, model architecture, and algorithmic configurations. These findings suggest that algorithm designers should carefully evaluate correlation assumptions under specific deployment scenarios rather than assuming that they are always present. Motivated by these findings, we propose two adaptive compression designs that actively switch between different compression modes based on the measured correlation strength, and we evaluate their performance gains relative to conventional non-adaptive approaches. In summary, our unified taxonomy provides a clean and principled foundation for developing more effective and application-specific compression techniques for FL systems.

2604.14725 2026-04-17 cs.DB cs.LG

RELOAD: A Robust and Efficient Learned Query Optimizer for Database Systems

Seokwon Lee, Jaeyoung Sim, Sihyun Kim, Yuhsing Li, Yiwen Zhu, Kwanghyun Park

Comments This work is currently under review

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英文摘要

Recent advances in query optimization have shifted from traditional rule-based and cost-based techniques towards machine learning-driven approaches. Among these, reinforcement learning (RL) has attracted significant attention due to its ability to optimize long-term performance by learning policies over query planning. However, existing RL-based query optimizers often exhibit unstable performance at the level of individual queries, including severe performance regressions, and require prolonged training to reach the plan quality of expert, cost-based optimizers. These shortcomings make learned query optimizers difficult to deploy in practice and remain a major barrier to their adoption in production database systems. To address these challenges, we present RELOAD, a robust and efficient learned query optimizer for database systems. RELOAD focuses on (i) robustness, by minimizing query-level performance regressions and ensuring consistent optimization behavior across executions, and (ii) efficiency, by accelerating convergence to expert-level plan quality. Through extensive experiments on standard benchmarks, including Join Order Benchmark, TPC-DS, and Star Schema Benchmark, RELOAD demonstrates up to 2.4x higher robustness and 3.1x greater efficiency compared to state-of-the-art RL-based query optimization techniques.

2604.14723 2026-04-17 cs.SE cs.AI

Bounded Autonomy for Enterprise AI: Typed Action Contracts and Consumer-Side Execution

Sarmad Sohail, Ghufran Haider

Comments 37 pages, 5 figures, 9 tables

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英文摘要

Large language models are increasingly used as natural-language interfaces to enterprise software, but their direct use as system operators remains unsafe. Model errors can propagate into unauthorized actions, malformed requests, cross-workspace execution, and other costly failures. We argue this is primarily an execution architecture problem. We present a bounded-autonomy architecture in which language models may interpret intent and propose actions, but all executable behavior is constrained by typed action contracts, permission-aware capability exposure, scoped context, validation before side effects, consumer-side execution boundaries, and optional human approval. The enterprise application remains the source of truth for business logic and authorization, while the orchestration engine operates over an explicit published actions manifest. We evaluate the architecture in a deployed multi-tenant enterprise application across three conditions: manual operation, unconstrained AI with safety layers disabled, and full bounded autonomy. Across 25 scenario trials spanning seven failure families, the bounded-autonomy system completed 23 of 25 tasks with zero unsafe executions, while the unconstrained configuration completed only 17 of 25. Two wrong-entity mutations escaped all consumer-contributed layers; only disambiguation and confirmation mechanisms intercept this class. Both AI conditions delivered 13-18x speedup over manual operation. Critically, removing safety layers made the system less useful: structured validation feedback guided the model to correct outcomes in fewer turns, while the unconstrained system hallucinated success. Several safety properties are structurally enforced by code and intercepted all targeted violations regardless of model output. The result is a practical, deployed architecture for making imperfect language models operationally useful in enterprise systems.

2604.14707 2026-04-17 cs.MM cs.SD

Geo2Sound: A Scalable Geo-Aligned Framework for Soundscape Generation from Satellite Imagery

Kunlin Wu, Yanning Wang, Haofeng Tan, Boyi Chen, Teng Fei, Xianping Ma, Yang Yue, Zan Zhou, Xiaofeng Liu

Comments 15 pages, 4 figures, 4 tables. Includes supplementary material and SatSound-Bench dataset details

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英文摘要

Recent image-to-audio models have shown impressive performance on object-centric visual scenes. However, their application to satellite imagery remains limited by the complex, wide-area semantic ambiguity of top-down views. While satellite imagery provides a uniquely scalable source for global soundscape generation, matching these views to real acoustic environments with unique spatial structures is inherently difficult. To address this challenge, we introduce Geo2Sound, a novel task and framework for generating geographically realistic soundscapes from satellite imagery. Specifically, Geo2Sound combines structural geospatial attributes modeling, semantic hypothesis expansion, and geo-acoustic alignment in a unified framework. A lightweight classifier summarizes overhead scenes into compact geographic attributes, multiple sound-oriented semantic hypotheses are used to generate diverse acoustically plausible candidates, and a geo-acoustic alignment module projects geographic attributes into the acoustic embedding space and identifies the candidate most consistent with the candidate sets. Moreover, we establish SatSound-Bench, the first benchmark comprising over 20k high-quality paired satellite images, text descriptions, and real-world audio recordings, collected from the field across more than 10 countries and complemented by three public datasets. Experiments show that Geo2Sound achieves a SOTA FAD of 1.765, outperforming the strongest baseline by 50.0%. Human evaluations further confirm substantial gains in both realism (26.5%) and semantic alignment, validating our high-fidelity synthesis on scale. Project page and source code: https://github.com/Blanketzzz/Geo2Sound

2604.14678 2026-04-17 eess.SY cs.RO cs.SY

Energy-based Regularization for Learning Residual Dynamics in Neural MPC for Omnidirectional Aerial Robots

Johannes Kübel, Henrik Krauss, Jinjie Li, Moju Zhao

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英文摘要

Data-driven Model Predictive Control (MPC) has lately been the core research subject in the field of control theory. The combination of an optimal control framework with deep learning paradigms opens up the possibility to accurately track control tasks without the need for complex analytical models. However, the system dynamics are often nuanced and the neural model lacks the potential to understand physical properties such as inertia and conservation of energy. In this work, we propose a novel energy-based regularization loss function which is applied to the training of a neural model that learns the residual dynamics of an omnidirectional aerial robot. Our energy-based regularization encourages the neural network to cause control corrections that stabilize the energy of the system. The residual dynamics are integrated into the MPC framework and improve the positional mean absolute error (MAE) over three real-world experiments by 23% compared to an analytical MPC. We also compare our method to a standard neural MPC implementation without regularization and primarily achieve a significantly increased flight stability implicitly due to the energy regularization and up to 15% lower MAE. Our code is available under: https://github.com/johanneskbl/jsk_aerial_robot/tree/develop/neural_MPC.

2604.14661 2026-04-17 cs.SE cs.AI cs.LG

AIPC: Agent-Based Automation for AI Model Deployment with Qualcomm AI Runtime

Jianhao Su, Zhanwei Wu, ShengTing Huang, Weidong Feng

Comments 19 pages, 1 figure, technical report

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Edge AI model deployment is a multi-stage engineering process involving model conversion, operator compatibility handling, quantization calibration, runtime integration, and accuracy validation. In practice, this workflow is long, failure-prone, and heavily dependent on deployment expertise, particularly when targeting hardware-specific inference runtimes. This technical report presents AIPC (AI Porting Conversion), an AI agent-driven approach for constrained automation of AI model deployment. AIPC decomposes deployment into standardized, verifiable stages and injects deployment-domain knowledge into agent execution through Agent Skills, helper scripts, and a stage-wise validation loop. This design reduces both the expertise barrier and the engineering time required for hardware deployment. Using Qualcomm AI Runtime (QAIRT) as the primary scenario, this report examines automated deployment across representative vision, multimodal, and speech models. In the cases covered here, AIPC can complete deployment from PyTorch to runnable QNN/SNPE inference within 7-20 minutes for structurally regular vision models, with indicative API costs roughly in the range of USD 0.7-10. For more complex models involving less-supported operators, dynamic shapes, or autoregressive decoding structures, fully automated deployment may still require further advances, but AIPC already provides practical support for execution, failure localization, and bounded repair.

2604.14624 2026-04-17 cs.SE cs.AI

Asking What Matters: Reward-Driven Clarification for Software Engineering Tasks

Sanidhya Vijayvargiya, Vijay Viswanathan, Graham Neubig

Comments 28 pages, 6 figures

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英文摘要

Humans often specify tasks incompletely, so assistants must know when and how to ask clarifying questions. However, effective clarification remains challenging in software engineering tasks as not all missing information is equally valuable, and questions must target information users can realistically provide. We study clarification in real software engineering tasks by quantifying which types of information most affect task success and which questions elicit useful responses from simulated users. Using Shapley attribution and distributional comparisons, we identify two key properties of effective clarification: task relevance (which information predicts success) and user answerability (what users can realistically provide). We operationalize these properties as multi-stage reinforcement learning rewards to train CLARITI, an 8B-parameter clarification module, that matches GPT-5's resolution rate on underspecified issues while generating 41% fewer questions. Our results suggest that grounding reward design in empirical analysis of information impact and user answerability improves clarification efficiency.

2604.14614 2026-04-17 cs.DS cs.LG

Tight Bounds for Learning Polyhedra with a Margin

Shyamal Patel, Santosh Vempala

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英文摘要

We give an algorithm for PAC learning intersections of $k$ halfspaces with a $ρ$ margin to within error $\varepsilon$ that runs in time $\textsf{poly}(k, \varepsilon^{-1}, ρ^{-1}) \cdot \exp \left(O(\sqrt{n \log(1/ρ) \log k})\right)$. Notably, this improves on prior work which had an exponential dependence on either $k$ or $ρ^{-1}$ and matches known cryptographic and Statistical Query lower bounds up to the logarithmic factors in $k$ and $ρ$ in the exponent. Our learning algorithm extends to the more general setting when we are only promised that most points have distance at least $ρ$ from the boundary of the polyhedron, making it applicable to continuous distributions as well.

2604.14613 2026-04-17 cs.IR cs.AI

Uncertainty-aware Generative Learning Path Recommendation with Cognition-Adaptive Diffusion

Xiangrui Xiong, Hang Liang, Baiyang Chen, Zifei Pan, Yanli Lee

Comments 20 pages, 4 figures

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英文摘要

Learning Path Recommendation (LPR) is critical for personalized education, yet current methods often fail to account for historical interaction uncertainty (e.g., lucky guesses or accidental slips) and lack adaptability to diverse learning goals. We propose U-GLAD (Uncertainty-aware Generative Learning Path Recommendation with Cognition-Adaptive Diffusion). To address representation bias, the framework models cognitive states as probability distributions, capturing the learner's underlying true state via a Gaussian LSTM. To ensure highly personalized recommendation, a goal-oriented concept encoder utilizes multi-head attention and objective-specific transformations to dynamically align concept semantics with individual learning goals, generating uniquely tailored embeddings. Unlike traditional discriminative ranking approaches, our model employs a generative diffusion model to predict the latent representation of the next optimal concept. Extensive evaluations on three public datasets demonstrate that U-GLAD significantly outperforms representative baselines. Further analyses confirm its superior capability in perceiving interaction uncertainty and providing stable, goal-driven recommendation paths.

2604.14604 2026-04-17 cs.CR cs.AI cs.SD

Hijacking Large Audio-Language Models via Context-Agnostic and Imperceptible Auditory Prompt Injection

Meng Chen, Kun Wang, Li Lu, Jiaheng Zhang, Tianwei Zhang

Comments Accepted by IEEE S&P 2026

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英文摘要

Modern Large audio-language models (LALMs) power intelligent voice interactions by tightly integrating audio and text. This integration, however, expands the attack surface beyond text and introduces vulnerabilities in the continuous, high-dimensional audio channel. While prior work studied audio jailbreaks, the security risks of malicious audio injection and downstream behavior manipulation remain underexamined. In this work, we reveal a previously overlooked threat, auditory prompt injection, under realistic constraints of audio data-only access and strong perceptual stealth. To systematically analyze this threat, we propose \textit{AudioHijack}, a general framework that generates context-agnostic and imperceptible adversarial audio to hijack LALMs. \textit{AudioHijack} employs sampling-based gradient estimation for end-to-end optimization across diverse models, bypassing non-differentiable audio tokenization. Through attention supervision and multi-context training, it steers model attention toward adversarial audio and generalizes to unseen user contexts. We also design a convolutional blending method that modulates perturbations into natural reverberation, making them highly imperceptible to users. Extensive experiments on 13 state-of-the-art LALMs show consistent hijacking across 6 misbehavior categories, achieving average success rates of 79\%-96\% on unseen user contexts with high acoustic fidelity. Real-world studies demonstrate that commercial voice agents from Mistral AI and Microsoft Azure can be induced to execute unauthorized actions on behalf of users. These findings expose critical vulnerabilities in LALMs and highlight the urgent need for dedicated defense.

2604.14603 2026-04-17 cs.IT cs.LG eess.SP math.IT

A Synonymous Variational Perspective on the Rate-Distortion-Perception Tradeoff

Zijian Liang, Kai Niu, Changshuo Wang, Jin Xu, Ping Zhang

Comments 23 pages, 6 figures. This paper is submitted to the special issue on "Data Compression: Classical Theories Meet Modern Advances" of the IEEE Journal of Selected Areas in Information Theory (IEEE JSAIT)

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The fundamental limit of natural signal compression has traditionally been characterized by classical rate-distortion (RD) theory through the tradeoff between coding rate and reconstruction distortion, while the rate-distortion-perception (RDP) framework introduces a divergence-based measure of perceptual quality as a modeling principle rather than a theoretically-derived principle, leaving its theoretical origin unclear. In this paper, motivated by a synonymity-based semantic information perspective, we reformulate perceptual reconstruction as recovering any admissible sample within an ideal synonymous set (synset) associated with the source, rather than the source sample itself, and correspondingly establish a synonymous source coding architecture. On this basis, we develop a synonymous variational inference (SVI) analysis framework with a synonymous variational lower bound (SVLBO) for tractable analysis of synset-oriented compression. Within this framework, we establish a synonymity-perception consistency principle, showing that optimal identification of semantic information is theoretically consistent with perceptual optimization. Based on its derivation result, we prove a synonymous RDP tradeoff for the proposed synonymous source coding. These analytical results show that the distributional divergence term arises naturally from the synset-based reconstruction objective, clarify its compatibility with existing RDP formulations and classical RD theory, and suggest the potential advantages of synonymous source coding.

2604.14552 2026-04-17 cs.PF cs.AR cs.LG

DEEP-GAP: Deep-learning Evaluation of Execution Parallelism in GPU Architectural Performance

Kathiravan Palaniappan

Comments 16 pages, 42 figures. Evaluation of inference performance on NVIDIA T4 and L4 GPUs across precision modes (FP32, FP16, INT8)

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Modern datacenters increasingly rely on low-power, single-slot inference accelerators to balance performance, energy efficiency, and rack density constraints. The NVIDIA T4 GPU has become widely deployed due to strong performance per watt and mature software support. Its successor, the NVIDIA L4 GPU, introduces improvements in Tensor Core throughput, cache capacity, memory bandwidth, and parallel execution capability. However, limited empirical evidence quantifies the practical inference performance gap between these two generations under controlled and reproducible conditions. This work introduces DEEP-GAP, a systematic evaluation extending the GDEV-AI methodology to GPU inference. Using identical configurations and workloads, we evaluate ResNet18, ResNet50, and ResNet101 across FP32, FP16, and INT8 precision modes using PyTorch and TensorRT. Results show that reduced precision significantly improves performance, with INT8 achieving up to 58x throughput improvement over CPU baselines. L4 achieves up to 4.4x higher throughput than T4 while reaching peak efficiency at smaller batch sizes between 16 and 32, improving latency-throughput tradeoffs for latency-sensitive workloads. T4 remains competitive for large batch workloads where cost or power efficiency is important. DEEP-GAP provides practical guidance for selecting precision modes, batch sizes, and GPU architectures for modern inference deployments.

2604.14512 2026-04-17 cs.CR cs.AI cs.FL cs.LO

CBCL: Safe Self-Extending Agent Communication

Hugo O'Connor

Comments 10 pages. Accepted at IEEE LangSec Workshop 2026 (camera-ready). Reference implementation, Lean 4 formalization, and verified parser: https://codeberg.org/anuna/cbcl-rs ; Nostr transport binding: https://codeberg.org/anuna/cbcl-nostr

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英文摘要

Agent communication languages (ACLs) enable heterogeneous agents to share knowledge and coordinate across diverse domains. This diversity demands extensibility, but expressive extension mechanisms can push the input language beyond the complexity classes where full validation is tractable. We present CBCL (Common Business Communication Language), an agent communication language that constrains all messages, including runtime language extensions, to the deterministic context-free language (DCFL) class. CBCL allows agents to define, transmit, and adopt domain-specific "dialect" extensions as first-class messages; three safety invariants (R1--R3), machine-checked in Lean 4 and enforced in a Rust reference implementation, prevent unbounded expansion, applying declared resource limits, and preserving core vocabulary. We formalize the language and its safety properties in Lean 4, implement a reference parser and dialect engine in Rust with property-based and differential tests, and extract a verified parser binary. Our results demonstrate that homoiconic protocol design, where extension definitions share the same representation as ordinary messages, can be made provably safe. As autonomous agents increasingly extend their own communication capabilities, formally bounding what they can express to each other is a precondition for oversight.

2604.14510 2026-04-17 cs.IR cs.AI

NewsTorch: A PyTorch-based Toolkit for Learner-oriented News Recommendation

Rongyao Wang, Veronica Liesaputra, Zhiyi Huang

Comments 3 papes

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英文摘要

News recommender systems are devised to alleviate the information overload, attracting more and more researchers' attention in recent years. The lack of a dedicated learner-oriented news recommendation toolkit hinders the advancement of research in news recommendation. We propose a PyTorch-based news recommendation toolkit called NewsTorch, developed to support learners in acquiring both conceptual understanding and practical experience. This toolkit provides a modular, decoupled, and extensible framework with a learner-friendly GUI platform that supports dataset downloading and preprocessing. It also enables training, validation, and testing of state-of-the-art neural news recommendation models with standardized evaluation metrics, ensuring fair comparison and reproducible experiments. Our open-source toolkit is released on Github: https://github.com/whonor/NewsTorch.

2604.14495 2026-04-17 cs.CE cs.AI cs.CR

Decoupling Identity from Utility: Privacy-by-Design Frameworks for Financial Ecosystems

Ifayoyinsola Ibikunle, Tyler Farnan, Senthil Kumar, Mayana Pereira

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Financial institutions face tension between maximizing data utility and mitigating the re-identification risks inherent in traditional anonymization methods. This paper explores Differentially Private (DP) synthetic data as a robust "Privacy by Design" framework to resolve this conflict, ensuring output privacy while satisfying stringent regulatory obligations. We examine two distinct generative paradigms: Direct Tabular Synthesis, which reconstructs high-fidelity joint distributions from raw data, and DP-Seeded Agent-Based Modeling (ABM), which uses DP-protected aggregates to parameterize complex, stateful simulations. While tabular synthesis excels at reflecting static historical correlations for QA testing and business analytics, the DP-Seeded ABM offers a forward-looking "counterfactual laboratory" capable of modeling dynamic market behaviors and black swan events. By decoupling individual identities from data utility, these methodologies eliminate traditional data-clearing bottlenecks, enabling seamless cross-institutional research and compliant decision-making in an evolving regulatory landscape.

2604.14456 2026-04-17 cs.HC cs.AI

FocalLens: Visualizing Narratives through Focalization

S M Raihanul Alam, Md Dilshadur Rahman, Md Naimul Hoque

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英文摘要

Visualizing narratives is useful to writers to reflect on unfinished drafts and identify unintentional biases and inconsistencies. Literary scholars can use the visualizations to identify nuanced patterns and literary styles from written text. Current narrative visualization is limited to representing character and location co-occurrences in a timeline, omitting important and complex narrative components such as focalization, causality, and speech. This paper aims to capture and visualize underexplored, complex narrative components as a basis for narrative visualization. As a starting point, we propose a new narrative visualization, named FocalLens, that uses focalization, the component that establishes who sees or perceives the events in a narrative, for representing the narrative. We provide the theoretical foundation of focalization and describe various types and facets of focalization. The details are incorporated in the novel visualization that captures how different characters perceive an event, who directly participate in an event, who indirectly observe the event, and who narrate the event. We also developed a tool that provides fluid interaction between the text and the proposed visualization. The tool was evaluated with four writers and scholars in a qualitative study, where writers analyzed their draft stories and scholars analyzed well-known stories. The findings suggest the tool added a new dimension to the workflow for writers and scholars, an analytical lens that is not available otherwise. We conclude by identifying design implications and future directions.

2604.14451 2026-04-17 astro-ph.CO cs.AI cs.CV physics.data-an

FAIR Universe Weak Lensing ML Uncertainty Challenge: Handling Uncertainties and Distribution Shifts for Precision Cosmology

Biwei Dai, Po-Wen Chang, Wahid Bhimji, Paolo Calafiura, Ragansu Chakkappai, Yuan-Tang Chou, Sascha Diefenbacher, Jordan Dudley, Ibrahim Elsharkawy, Steven Farrell, Isabelle Guyon, Chris Harris, Elham E Khoda, Benjamin Nachman, David Rousseau, Uroš Seljak, Ihsan Ullah, Yulei Zhang

Comments Whitepaper for the FAIR Universe Weak Lensing ML Uncertainty Challenge Competition. More info is available at our GitHub repository https://github.com/FAIR-Universe/Cosmology_Challenge. 13 pages, 5 figures, 1 table

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Weak gravitational lensing, the correlated distortion of background galaxy shapes by foreground structures, is a powerful probe of the matter distribution in our universe and allows accurate constraints on the cosmological model. In recent years, high-order statistics and machine learning (ML) techniques have been applied to weak lensing data to extract the nonlinear information beyond traditional two-point analysis. However, these methods typically rely on cosmological simulations, which poses several challenges: simulations are computationally expensive, limiting most realistic setups to a low training data regime; inaccurate modeling of systematics in the simulations create distribution shifts that can bias cosmological parameter constraints; and varying simulation setups across studies make method comparison difficult. To address these difficulties, we present the first weak lensing benchmark dataset with several realistic systematics and launch the FAIR Universe Weak Lensing Machine Learning Uncertainty Challenge. The challenge focuses on measuring the fundamental properties of the universe from weak lensing data with limited training set and potential distribution shifts, while providing a standardized benchmark for rigorous comparison across methods. Organized in two phases, the challenge will bring together the physics and ML communities to advance the methodologies for handling systematic uncertainties, data efficiency, and distribution shifts in weak lensing analysis with ML, ultimately facilitating the deployment of ML approaches into upcoming weak lensing survey analysis.

2604.14444 2026-04-17 cs.CR cs.AI

Robustness Analysis of Machine Learning Models for IoT Intrusion Detection Under Data Poisoning Attacks

Fortunatus Aabangbio Wulnye, Justice Owusu Agyemang, Kwame Opuni-Boachie Obour Agyekum, Kwame Agyeman-Prempeh Agyekum, Kingsford Sarkodie Obeng Kwakye, Francisca Adomaa Acheampong

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Ensuring the reliability of machine learning-based intrusion detection systems remains a critical challenge in Internet of Things (IoT) environments, particularly as data poisoning attacks increasingly threaten the integrity of model training pipelines. This study evaluates the susceptibility of four widely used classifiers, Random Forest, Gradient Boosting Machine, Logistic Regression, and Deep Neural Network models, against multiple poisoning strategies using three real-world IoT datasets. Results show that while ensemble-based models exhibit comparatively stable performance, Logistic Regression and Deep Neural Networks suffer degradation of up to 40% under label manipulation and outlier-based attacks. Such disruptions significantly distort decision boundaries, reduce detection fidelity, and undermine deployment readiness. The findings highlight the need for adversarially robust training, continuous anomaly monitoring, and feature-level validation within operational Network Intrusion Detection Systems. The study also emphasizes the importance of integrating resilience testing into regulatory and compliance frameworks for AI-driven IoT security. Overall, this work provides an empirical foundation for developing more resilient intrusion detection pipelines and informs future research on adaptive, attack-aware models capable of maintaining reliability under adversarial IoT conditions.