Vision Transformers rely on positional embeddings and class tokens encoding fixed spatial priors. While effective for natural images, these priors may be suboptimal when spatial layout is weakly informative, a frequent condition in medical imaging. We introduce ZACH-ViT (Zero-token Adaptive Compact Hierarchical Vision Transformer), a compact Vision Transformer that removes positional embeddings and the [CLS] token, achieving permutation-invariant patch processing via global average pooling. Zero-token denotes removal of the dedicated aggregation token and positional encodings. Patch tokens remain unchanged. Adaptive residual projections preserve training stability under strict parameter constraints. We evaluate ZACH-ViT across seven MedMNIST datasets under a strict few-shot protocol (50 samples/class, fixed hyperparameters, five seeds). Results reveal regime-dependent behavior: ZACH-ViT (0.25M parameters, trained from scratch) achieves strongest advantage on BloodMNIST and remains competitive on PathMNIST, while relative advantage decreases on datasets with stronger anatomical priors (OCTMNIST, OrganAMNIST), consistent with our hypothesis. Component and pooling ablations show positional support becomes mildly beneficial as spatial structure increases, whereas reintroducing a [CLS] token is consistently unfavorable. These findings support that architectural alignment with data structure can outweigh universal benchmark dominance. Despite minimal size and no pretraining, ZACH-ViT achieves competitive performance under data-scarce conditions, relevant for compact medical imaging and low-resource settings. Code: https://github.com/Bluesman79/ZACH-ViT

Robot failure is detrimental and disruptive, often requiring human intervention to recover. Our vision is 'fail-active' operation, allowing robots to safely complete their tasks even when damaged. Focusing on 'actuation failures', we introduce DEFT, a diffusion-based trajectory generator conditioned on the robot's current embodiment and task constraints. DEFT generalizes across failure types, supports constrained and unconstrained motions, and enables task completion under arbitrary failure. We evaluate DEFT in both simulation and real-world scenarios using a 7-DoF robotic arm. DEFT outperforms its baselines over thousands of failure conditions, achieving a 99.5% success rate for unconstrained motions versus RRT's 42.4%, and 46.4% for constrained motions versus differential IK's 30.9%. Furthermore, DEFT demonstrates robust zero-shot generalization by maintaining performance on failure conditions unseen during training. Finally, we perform real-world evaluations on two multi-step tasks, drawer manipulation and whiteboard erasing. These experiments demonstrate DEFT succeeding on tasks where classical methods fail. Our results show that DEFT achieves fail-active manipulation across arbitrary failure configurations and real-world deployments.

Molecular subtyping of PDAC into basal-like and classical has established prognostic and predictive value. However, its use in clinical practice is limited by cost, turnaround time, and tissue requirements, thereby restricting its application in the management of PDAC. We introduce PanSubNet, an interpretable deep learning framework that predicts therapy-relevant molecular subtypes directly from standard H&E-stained WSIs. PanSubNet was developed using data from 1,055 patients across two multi-institutional cohorts (PANCAN, n=846; TCGA, n=209) with paired histology and RNA-seq data. Ground-truth labels were derived using the validated Moffitt 50-gene signature refined by GATA6 expression. The model employs dual-scale architecture that fuses cellular-level morphology with tissue-level architecture, leveraging attention mechanisms for multi-scale representation learning and transparent feature attribution. On internal validation within PANCAN using five-fold cross-validation, PanSubNet achieved mean AUC of 88.5% with balanced sensitivity and specificity. External validation on the independent TCGA cohort without fine-tuning demonstrated robust generalizability (AUC 84.0%). PanSubNet preserved and, in metastatic disease, strengthened prognostic stratification compared to RNA-seq based labels. Prediction uncertainty linked to intermediate transcriptional states, not classification noise. Model predictions are aligned with established transcriptomic programs, differentiation markers, and DNA damage repair signatures. By enabling rapid, cost-effective molecular stratification from routine H&E-stained slides, PanSubNet offers a clinically deployable and interpretable tool for genetic subtyping. We are gathering data from two institutions to validate and assess real-world performance, supporting integration into digital pathology workflows and advancing precision oncology for PDAC.

Aiming to advance research in the field of interpretability of deep learning models for tree species classification using TLS 3D point clouds we present insights in the classification abilities of YOLOv8 through a new framework which enables systematic analysis of saliency maps derived from CAM (Class Activation Mapping). To investigate the contribution of structural tree features to the classification decisions of the models, we link regions with high saliency derived from the application of Finer-CAM to segments of 2D side-view images that correspond to structural tree features. Using TLS 3D point clouds from 2445 trees across seven European tree species, we trained five YOLOv8 models with cross-validation, reaching a mean accuracy of 96% (SD = 0.24%) when applied to the test data. Our results demonstrate that Finer-CAM can be considered faithful in identifying discriminative regions that discriminate target tree species. This renders Finer-CAM suitable for enhancing the interpretability of the tree species classification models. Analysis of 630 saliency maps indicate that the models primarily rely on image regions associated with tree crowns for species classification. While this result is pronounced in Silver Birch, European Beech, English oak, and Norway Spruce, image regions associated with stems contribute more frequently to the differentiation of European ash, Scots pine, and Douglas-fir. We demonstrate that the visibility of detailed structural tree features in the 2D side-view images enhances the discriminative performances of the models, indicating YOLOv8`s abilities to leverage detailed point cloud representations. Our results represent a first step toward enhancing the understanding of the classification decision processes of tree species classification models, aiding in the identification of data set and model limitations, and building confidence in model predictions.

Structure-from-Motion (SfM) is a fundamental technique for recovering camera poses and scene structure from multi-view imagery, serving as a critical upstream component for applications ranging from 3D reconstruction to modern neural scene representations such as 3D Gaussian Splatting. However, most mature SfM systems remain CPU-centric and built upon traditional optimization toolchains, creating a growing mismatch with modern GPU-based, learning-driven pipelines and limiting scalability in large-scale scenes. While recent advances in GPU-accelerated bundle adjustment (BA) have demonstrated the potential of parallel sparse optimization, extending these techniques to build a complete global SfM system remains challenging due to unresolved issues in metric scale recovery and numerical robustness. In this paper, we implement a fully GPU-based and PyTorch-compatible global SfM system, named InstantSfM, to integrate seamlessly with modern learning pipelines. InstantSfM embeds metric depth priors directly into both global positioning and BA through a depth-constrained Jacobian structure, thereby resolving scale ambiguity within the optimization framework. To ensure numerical stability, we employ explicit filtering of under-constrained variables for the Jacobian matrix in an optimized GPU-friendly manner. Extensive experiments on diverse datasets demonstrate that InstantSfM achieves state-of-the-art efficiency while maintaining reconstruction accuracy comparable to both established classical pipelines and recent learning-based methods, showing up to ${\sim40\times}$ speedup over COLMAP on large-scale scenes.

Evaluating multi-turn interactive agents is challenging due to the need for human assessment. Evaluation with simulated users has been introduced as an alternative, however existing approaches typically model generic users and overlook the domain-specific principles required to capture realistic behavior. We propose SAGE, a novel user Simulation framework for multi-turn AGent Evaluation that integrates knowledge from business contexts. SAGE incorporates top-down knowledge rooted in business logic, such as ideal customer profiles, grounding user behavior in realistic customer personas. We further integrate bottom-up knowledge taken from business agent infrastructure (e.g., product catalogs, FAQs, and knowledge bases), allowing the simulator to generate interactions that reflect users' information needs and expectations in a company's target market. Through empirical evaluation, we find that this approach produces interactions that are more realistic and diverse, while also identifying up to 33% more agent errors, highlighting its effectiveness as an evaluation tool to support bug-finding and iterative agent improvement.

Clustering is a fundamental unsupervised learning task with applications across a wide range of domains. Popular algorithms such as $k$-means are efficient and widely used, but can be sensitive to outliers, ambiguous boundary points, and heterogeneous cluster geometry, which may distort centroid estimates and yield suboptimal partitions. We introduce K-Sil, a silhouette-driven $k$-means variant that, at each iteration, weights points using a centroid-margin proxy for the silhouette score, emphasizing confidently assigned instances while down-weighting borderline or noisy regions. Centroid updates take the form of a softmax-weighted mean, and an adaptive temperature automatically calibrates the sharpness of the weight distribution using a cluster-balanced, macro-averaged, silhouette criterion. Under standard separation conditions, we establish a local convergence result for the induced weighted centroid updates. Experiments on 15 real-world datasets spanning tabular, biomedical, text, and image representations show consistent gains in internal validation metrics and typical improvements in external validation metrics over $k$-means and competitive instance-weighted baselines.

Modern neural sequence models are designed to meet the dual mandate of parallelizable training and fast sequential inference. Recent developments have given rise to various models, such as Gated Linear Attention (GLA) and Mamba, that achieve such ``sequential-parallel duality.'' This raises a natural question: can we characterize the full class of neural sequence models that support near-constant-time parallel evaluation and linear-time, constant-space sequential inference? We begin by describing a broad class of such models -- state space models -- as those whose state updates can be computed using the classic parallel prefix scan algorithm with a custom associative aggregation operator. We then define a more general class, Prefix-Scannable Models (PSMs), by relaxing the state aggregation operator to allow arbitrary (potentially non-associative) functions such as softmax attention. This generalization unifies many existing architectures, including element-wise RNNs (e.g., Mamba) and linear transformers (e.g., GLA, Mamba2, mLSTM), while also introducing new models with softmax-like operators that achieve O(1) amortized compute per token and log(N) memory for sequence length N. We empirically evaluate such models on illustrative small-scale language modeling and canonical synthetic tasks, including state tracking and associative recall. Empirically, we find that PSMs retain the expressivity of transformer-based architectures while matching the inference efficiency of state space models -- in some cases exhibiting better length generalization than either.

Recent advances in large language model (LLM) reasoning have shown that sophisticated behaviors such as planning and self-reflection can emerge through reinforcement learning (RL). However, despite these successes, RL in its current form remains insufficient to induce capabilities that exceed the limitations of the base model, as it is primarily optimized based on existing knowledge of the model rather than facilitating the acquisition of new information. To address this limitation, we employ supervised fine-tuning (SFT) to learn what RL cannot, which enables the incorporation of new knowledge and reasoning patterns by leveraging high-quality demonstration data. We analyze the training dynamics of RL and SFT for LLM reasoning and find that RL excels at maintaining and improving performance on questions within the model's original capabilities, while SFT is more effective at enabling progress on questions beyond the current scope of the model. Motivated by the complementary strengths of RL and SFT, we introduce a novel training approach, \textbf{ReLIFT} (\textbf{Re}inforcement \textbf{L}earning \textbf{I}nterleaved with Online \textbf{F}ine-\textbf{T}uning). In ReLIFT, the model is primarily trained using RL, but when it encounters challenging questions, high-quality solutions are collected for fine-tuning, and the training process alternates between RL and fine-tuning to enhance the model's reasoning abilities. ReLIFT achieves an average improvement of over +5.2 points across five competition-level benchmarks and one out-of-distribution benchmark compared to other zero-RL models. Furthermore, we demonstrate that ReLIFT outperforms both RL and SFT while using only 13\% of the detailed demonstration data, highlighting its scalability. These results provide compelling evidence that ReLIFT overcomes the fundamental limitations of RL and underscores the significant potential.

Current color fundus image registration approaches are limited, among other things, by the lack of labeled data, which is even more significant in the medical domain, motivating the use of unsupervised learning. Therefore, in this work, we develop a novel unsupervised descriptor learning method that does not rely on keypoint detection. This enables the resulting descriptor network to be agnostic to the keypoint detector used during the registration inference. To validate this approach, we perform an extensive and comprehensive comparison on the reference public retinal image registration dataset. Additionally, we test our method with multiple keypoint detectors of varied nature, even proposing some novel ones. Our results demonstrate that the proposed approach offers accurate registration, not incurring in any performance loss versus supervised methods. Additionally, it demonstrates accurate performance regardless of the keypoint detector used. Thus, this work represents a notable step towards leveraging unsupervised learning in the medical domain.

Deep noise suppression (DNS) models enjoy widespread use throughout a variety of high-stakes speech applications. However, we show that four recent DNS models can each be reduced to outputting unintelligible gibberish through the addition of psychoacoustically hidden adversarial noise, even in low-background-noise and simulated over-the-air settings. For three of the models, a small transcription study with audio and multimedia experts confirms unintelligibility of the attacked audio; simultaneously, an ABX study shows that the adversarial noise is generally imperceptible, with some variance between participants and samples. While we also establish several negative results around targeted attacks and model transfer, our results nevertheless highlight the need for practical countermeasures before open-source DNS systems can be used in safety-critical applications.

Partial differential equations (PDEs) are widely used to model complex physical systems, but solving them efficiently remains a significant challenge. Recently, Transformers have emerged as the preferred architecture for PDEs due to their ability to capture intricate dependencies. However, they struggle with representing continuous dynamics and long-range interactions. To overcome these limitations, we introduce the Mamba Neural Operator (MNO), a novel framework that enhances neural operator-based techniques for solving PDEs. MNO establishes a formal theoretical connection between structured state-space models (SSMs) and neural operators, offering a unified structure that can adapt to diverse architectures, including Transformer-based models. By leveraging the structured design of SSMs, MNO captures long-range dependencies and continuous dynamics more effectively than traditional Transformers. Through extensive analysis, we show that MNO significantly boosts the expressive power and accuracy of neural operators, making it not just a complement but a superior framework for PDE-related tasks, bridging the gap between efficient representation and accurate solution approximation. Our code is available on https://github.com/Math-ML-X/Mamba-Neural-Operator

Large language models are increasingly adopted as semantic backbones for neural text-to-speech systems. However, frozen LLM representations are insufficient for modeling speaker specific acoustic and perceptual characteristics. Our experiments involving fine tuning of the Language Model backbone of TTS show promise in improving the voice consistency and Signal to Noise ratio SNR in voice cloning task. Across multiple speakers LoRA finetuning consistently outperforms the non-finetuned base Qwen-0.5B model across three complementary dimensions of speech quality. First, perceptual quality improves significantly with DNS-MOS gains of up to 0.42 points for speakers whose training data exhibits sufficient acoustic variability. Second, speaker fidelity improves for all evaluated speakers with consistent increases in voice similarity indicating that LoRA effectively adapts speaker identity representations without degrading linguistic modeling. Third, signal level quality improves in most cases with signal to noise ratio increasing by as much as 34 percent. Crucially these improvements are strongly governed by the characteristics of the training data. Speakers with high variability in acoustic energy and perceptual quality achieve simultaneous gains in DNS-MOS voice similarity and SNR. Overall this work establishes that LoRA finetuning is not merely a parameter efficient optimization technique but an effective mechanism for better speaker level adaptation in compact LLM-based TTS systems. When supported by sufficiently diverse training data LoRA adapted Qwen-0.5B consistently surpasses its frozen base model in perceptual quality speaker similarity with low latency using GGUF model hosted in quantized form.

Transformer-based large language models (LLMs) rely on key-value (KV) caching to avoid redundant computation during autoregressive inference. While this mechanism greatly improves efficiency, the cache size grows linearly with the input sequence length, quickly becoming a bottleneck for long-context tasks. Existing solutions mitigate this problem by evicting prompt KV that are deemed unimportant, guided by estimated importance scores. Notably, a recent line of work proposes to improve eviction quality by "glimpsing into the future", in which a draft generator produces a surrogate future response approximating the target model's true response, and this surrogate is subsequently used to estimate the importance of cached KV more accurately. However, these approaches rely on computationally expensive draft generation, which introduces substantial prefilling overhead and limits their practicality in real-world deployment. To address this challenge, we propose LookaheadKV, a lightweight eviction framework that leverages the strength of surrogate future response without requiring explicit draft generation. LookaheadKV augments transformer layers with parameter-efficient modules trained to predict true importance scores with high accuracy. Our design ensures negligible runtime overhead comparable to existing inexpensive heuristics, while achieving accuracy superior to more costly approximation methods. Extensive experiments on long-context understanding benchmarks, across a wide range of models, demonstrate that our method not only outperforms recent competitive baselines in various long-context understanding tasks, but also reduces the eviction cost by up to 14.5x, leading to significantly faster time-to-first-token. Our code is available at https://github.com/SamsungLabs/LookaheadKV.

In reinforcement learning, we typically aim to optimize the expected value of the sum of rewards an agent collects over a trajectory. However, if the process generating these rewards is non-ergodic, the expected value, i.e., the average over infinitely many trajectories with a given policy, is uninformative for the average over a single, but infinitely long trajectory. Thus, if we care about how the individual agent performs during deployment, the expected value is not a good optimization objective. In this paper, we discuss the impact of non-ergodic reward processes on reinforcement learning agents through an instructive example, relate the notion of ergodic reward processes to more widely used notions of ergodic Markov chains, and present existing solutions that optimize long-term performance of individual trajectories under non-ergodic reward dynamics.

Explicit 3D representations have already become an essential medium for 3D simulation and understanding. However, the most commonly used point cloud and 3D Gaussian Splatting (3DGS) each suffer from non-photorealistic rendering and significant degradation under sparse inputs. In this paper, we introduce Sparse to Dense lifting (S2D), a novel pipeline that bridges the two representations and achieves high-quality 3DGS reconstruction with minimal inputs. Specifically, the S2D lifting is two-fold. We first present an efficient one-step diffusion model that lifts sparse point cloud for high-fidelity image artifact fixing. Meanwhile, to reconstruct 3D consistent scenes, we also design a corresponding reconstruction strategy with random sample drop and weighted gradient for robust model fitting from sparse input views to dense novel views. Extensive experiments show that S2D achieves the best consistency in generating novel view guidance and first-tier sparse view reconstruction quality under different input sparsity. By reconstructing stable scenes with the least possible captures among existing methods, S2D enables minimal input requirements for 3DGS applications.

Medication errors pose a significant threat to patient safety, making pharmacist verification (PV) a critical, yet heavily burdened, final safeguard. The direct application of Large Language Models (LLMs) to this zero-tolerance domain is untenable due to their inherent factual unreliability, lack of traceability, and weakness in complex reasoning. To address these challenges, we introduce PharmGraph-Auditor, a novel system designed for safe and evidence-grounded prescription auditing. The core of our system is a trustworthy Hybrid Pharmaceutical Knowledge Base (HPKB), implemented under the Virtual Knowledge Graph (VKG) paradigm. This architecture strategically unifies a relational component for set constraint satisfaction and a graph component for topological reasoning via a rigorous mapping layer. To construct this HPKB, we propose the Iterative Schema Refinement (ISR) algorithm, a framework that enables the co-evolution of both graph and relational schemas from medical texts. For auditing, we introduce the KB-grounded Chain of Verification (CoV), a new reasoning paradigm that transforms the LLM from an unreliable generator into a transparent reasoning engine. CoV decomposes the audit task into a sequence of verifiable queries against the HPKB, generating hybrid query plans to retrieve evidence from the most appropriate data store. Experimental results demonstrate robust knowledge extraction capabilities and show promises of using PharmGraph-Auditor to enable pharmacists to achieve safer and faster prescription verification.

Separating thin, flexible layers that must be individually grasped is a common but challenging manipulation primitive for most off-the-shelf grippers. A prominent example arises in clinical settings: the opening of sterile flat pouches for the preparation of the operating room, where the first step is to separate and grasp the flaps. We present a novel gripper design and opening strategy that enables reliable flap separation and robust seal opening. This capability addresses a high-volume repetitive hospital procedure in which nurses manually open up to 240 bags per shift, a physically demanding task linked to musculoskeletal injuries. Our design combines an active dented-roller fingertip with compliant fingers that exploit environmental constraints to robustly grasp thin flexible flaps. Experiments demonstrate that the proposed gripper reliably grasps and separates sealed bag flaps and other thin-layered materials from the hospital, the most sensitive variable affecting performance being the normal force applied. When two copies of the gripper grasp both flaps, the system withstands the forces needed to open the seals robustly. To our knowledge, this is one of the first demonstrations of robotic assistance to automate this repetitive, low-value, but critical hospital task.

Healthcare professionals work in complex, high-stakes environments where effective communication is critical for care delivery, team coordination, and individual well-being. However, communication activity in everyday clinical settings remains challenging to measure and largely unexplored in human behavioral research. We present VoxCare, a scalable egocentric wearable audio sensing and computing system that captures natural communication behaviors of hospital professionals in real-world settings without storing raw audio. VoxCare performs real-time, on-device acoustic feature extraction and applies a speech foundation model-guided teacher-student framework to identify foreground speech activity. From these features, VoxCare derives interpretable behavioral measures of communication frequency, duration, and vocal arousal. Our analyses reveal how, when, and how often clinicians communicate across different shifts and working units, and suggest that communication activity reflects underlying workload and stress. By enabling continuous assessment of communication patterns in everyday contexts, this study provides data-driven approaches to understand the behaviors of healthcare providers and ultimately improve healthcare delivery.

Reinforcement learning (RL) finetuning has become a key technique for enhancing the reasoning abilities of large language models (LLMs). However, its effectiveness critically depends on the selection of training data. Recent advances underscore the importance of online prompt selection methods, which typically concentrate training on partially solved or moderately challenging examples under the current policy, thereby yielding more effective model updates. While significantly accelerating RL finetuning in terms of training steps, they also incur substantial computational overhead by requiring extensive LLM rollouts over large candidate batches to identify informative samples, an expense that can outweigh the finetuning process itself. To address this challenge, this work proposes Dynamics-Predictive Sampling (DPS), which online predicts and selects informative prompts by inferring their learning dynamics prior to costly rollouts. Specifically, we introduce a new perspective by modeling each prompt's solving progress during RL finetuning as a dynamical system, where the extent of solving is represented as the state and the transition is characterized by a hidden Markov model. Using historical rollout reward signals, we perform online Bayesian inference to estimate evolving state distributions, and the inference outcome provides a predictive prior for efficient prompt selection without rollout-intensive filtering. Empirical results across diverse reasoning tasks, including mathematics, planning, and visual geometry, demonstrate that DPS substantially reduces redundant rollouts, accelerates the training process, and achieves superior reasoning performance.

We present a parameter-efficient Diffusion Transformer (DiT) for generating 200bp cell-type-specific regulatory DNA sequences. By replacing the U-Net backbone of DNA-Diffusion with a transformer denoiser equipped with a 2D CNN input encoder, our model matches the U-Net's best validation loss in 13 epochs (60$\times$ fewer) and converges 39% lower, while reducing memorization from 5.3% to 1.7% of generated sequences aligning to training data via BLAT. Ablations show the CNN encoder is essential: without it, validation loss increases 70% regardless of positional embedding choice. We further apply DDPO finetuning using Enformer as a reward model, achieving a 38$\times$ improvement in predicted regulatory activity. Cross-validation against DRAKES on an independent prediction task confirms that improvements reflect genuine regulatory signal rather than reward model overfitting.

Knowledge distillation (KD) methods are pivotal in compressing large pre-trained language models into smaller models, ensuring computational efficiency without significantly dropping performance. Traditional KD techniques assume homogeneity in modalities between the teacher (source) and the student (target) models. On the other hand, existing multimodal knowledge distillation methods require modality-specific pre-training of the teacher model, which is computationally infeasible in most cases. In this paper, we introduce ARMADA, an efficient cross-modal knowledge distillation framework designed to transfer knowledge from large vision-language models, including black-box models, to language-only models. Unlike existing KD techniques that rely on the internal structures of multimodal teachers or require computationally expensive pre-training, ARMADA leverages novel alignment techniques to distil knowledge without altering the teacher model, ensuring efficiency and scalability. We empirically validate ARMADA on twelve natural language understanding, eight complex generative reasoning and five instruction-tuning tasks, demonstrating consistent performance improvements in large models such as DeBERTa-v2-1.4B, OPT-1.3B, LLaMA-{3B, 7B, 8B}. ARMADA achieves up to 3.4% improvement on language understanding tasks and 2.6% boost in generative reasoning, all without requiring expensive multimodal pre-training or fine-tuning of the teacher model. Our findings challenge conventional knowledge distillation paradigms by demonstrating that even vision-language models, despite lacking direct textual understanding, can significantly enhance language models when distilled appropriately.

Subject indexing is vital for discovery but hard to sustain at scale and across languages. We release a large bilingual (English/German) corpus of catalog records annotated with the Integrated Authority File (GND), plus a machine-actionable GND taxonomy. The resource enables ontology-aware multi-label classification, mapping text to authority terms, and agent-assisted cataloging with reproducible, authority-grounded evaluation. We provide a brief statistical profile and qualitative error analyses of three systems. We invite the community to assess not only accuracy but usefulness and transparency, toward authority-anchored AI co-pilots that amplify catalogers' work.

Polygenic risk scores and other genomic analyses require large individual-level genotype datasets, yet strict data access restrictions impede sharing. Synthetic genotype generation offers a privacy-preserving alternative, but most existing methods operate unconditionally, producing samples without phenotype alignment, or rely on unsupervised compression, creating a gap between statistical fidelity and downstream task utility. We present SNPgen, a two-stage conditional latent diffusion framework for generating phenotype-supervised synthetic genotypes. SNPgen combines GWAS-guided variant selection (1,024-2,048 trait-associated SNPs) with a variational autoencoder for genotype compression and a latent diffusion model conditioned on binary disease labels via classifier-free guidance. Evaluated on 458,724 UK Biobank individuals across four complex diseases (coronary artery disease, breast cancer, type 1 and type 2 diabetes), models trained on synthetic data matched real-data predictive performance in a train-on-synthetic, test-on-real protocol, approaching genome-wide PRS methods that use $2$-$6\times$ more variants. Privacy analysis confirmed zero identical matches, near-random membership inference (AUC $\approx 0.50$), preserved linkage disequilibrium structure, and high allele frequency correlation ($r \geq 0.95$) with source data. A controlled simulation with known causal effects verified faithful recovery of the imposed genetic association structure.

Learning-based real image dehazing methods have achieved notable progress, yet they still face adaptation challenges in diverse real haze scenes. These challenges mainly stem from the lack of effective unsupervised mechanisms for unlabeled data and the heavy cost of full model fine-tuning. To address these challenges, we propose the haze-to-clear text-directed loss that leverages CLIP's cross-modal capabilities to reformulate real image dehazing as a semantic alignment problem in latent space, thereby providing explicit unsupervised cross-modal guidance in the absence of reference images. Furthermore, we introduce the Bilevel Layer-positioning LoRA (BiLaLoRA) strategy, which learns both the LoRA parameters and automatically search the injection layers, enabling targeted adaptation of critical network layers. Extensive experiments demonstrate our superiority against state-of-the-art methods on multiple real-world dehazing benchmarks. The code is publicly available at https://github.com/YanZhang-zy/BiLaLoRA.

Recent advancements in integrating tactile sensing into vision-language-action (VLA) models have demonstrated transformative potential for robotic perception. However, existing tactile representations predominantly rely on qualitative descriptors (e.g., texture), neglecting quantitative contact states such as force magnitude, contact geometry, and principal axis orientation, which are indispensable for fine-grained manipulation. To bridge this gap, we propose FG-CLTP, a fine-grained contrastive language tactile pretraining framework. We first introduce a novel dataset comprising over 100k tactile 3D point cloud-language pairs that explicitly capture multidimensional contact states from the sensor's perspective. We then implement a discretized numerical tokenization mechanism to achieve quantitative-semantic alignment, effectively injecting explicit physical metrics into the multimodal feature space. The proposed FG-CLTP model yields a 95.9% classification accuracy and reduces the regression error (MAE) by 52.6% compared to state-of-the-art methods. Furthermore, the integration of 3D point cloud representations establishes a sensor-agnostic foundation with a minimal sim-to-real gap of 3.5%. Building upon this fine-grained representation, we develop a 3D tactile-language-action (3D-TLA) architecture driven by a flow matching policy to enable multimodal reasoning and control. Extensive experiments demonstrate that our framework significantly outperforms strong baselines in contact-rich manipulation tasks, providing a robust and generalizable foundation for tactile-language-action models.

Despite the remarkable capabilities of Multimodal Large Language Models (MLLMs), they still suffer from visual fading in long-context scenarios. Specifically, the attention to visual tokens diminishes as the text sequence lengthens, leading to text generation detached from visual constraints. We attribute this degradation to the inherent inductive bias of Multimodal RoPE, which penalizes inter-modal attention as the distance between visual and text tokens increases. To address this, we propose inter-modal Distance Invariant Position Encoding (DIPE), a simple but effective mechanism that disentangles position encoding based on modality interactions. DIPE retains the natural relative positioning for intra-modal interactions to preserve local structure, while enforcing an anchored perceptual proximity for inter-modal interactions. This strategy effectively mitigates the inter-modal distance-based penalty, ensuring that visual signals remain perceptually consistent regardless of the context length. Experimental results demonstrate that by integrating DIPE with Multimodal RoPE, the model maintains stable visual grounding in long-context scenarios, significantly alleviating visual fading while preserving performance on standard short-context benchmarks. Code is available at https://github.com/lchen1019/DIPE.

Recent advancements in Speech Large Language Models have significantly enhanced multi-dimensional speech understanding. However, the majority of high-performance frameworks are predominantly optimized for GPU centric ecosystems and proprietary backbones, creating a significant gap for deployment on non-CUDA computing infrastructures. In this paper, we present OSUM-Pangu, a fully open-source speech understanding foundation model developed on a completely non-CUDA software and hardware stack. By integrating an audio encoder with the openPangu-7B LLM backbone, we successfully implement the entire training and inference pipeline on the Ascend NPU platform. To facilitate efficient task alignment under non-CUDA resource constraints, we adopt a practical training process that sequentially bridges speech perception and user intent recognition. Experimental results demonstrate that OSUM-Pangu achieves task accuracy comparable to mainstream GPU-based models while maintaining robust natural language interaction capabilities. Our work provides a reproducible, non-CUDA baseline for the open-source speech community, promoting the independent evolution of multimodal intelligence.

SiDiaC-v.2.0 is the largest comprehensive Sinhala Diachronic Corpus to date, covering a period from 1800 CE to 1955 CE in terms of publication dates, and a historical span from the 5th to the 20th century CE in terms of written dates. The corpus consists of 244k words across 185 literary works that underwent thorough filtering, preprocessing, and copyright compliance checks, followed by extensive post-processing. Additionally, a subset of 59 documents totalling 70k words was annotated based on their written dates. Texts from the National Library of Sri Lanka were selected from the SiDiaC-v.1.0 non-filtered list, which was digitised using Google Document AI OCR. This was followed by post-processing to correct formatting issues, address code-mixing, include special tokens, and fix malformed tokens. The construction of SiDiaC-v.2.0 was informed by practices from other corpora, such as FarPaHC, SiDiaC-v.1.0, and CCOHA. This was particularly relevant for syntactic annotation and text normalisation strategies, given the shared characteristics of low-resource language status between Faroese and the similar cleaning strategies utilised in CCOHA. This corpus is categorised into two layers based on genres: primary and secondary. The primary categorisation is binary, assigning each book to either Non-Fiction or Fiction. The secondary categorisation is more detailed, grouping texts under specific genres such as Religious, History, Poetry, Language, and Medical. Despite facing challenges due to limited resources, SiDiaC-v.2.0 serves as a comprehensive resource for Sinhala NLP, building upon the work previously done in SiDiaC-v.1.0.

Advancing Multi-Agent Pathfinding (MAPF) and Multi-Robot Motion Planning (MRMP) requires platforms that enable transparent, reproducible comparisons across modeling choices. Existing tools either scale under simplifying assumptions (grids, homogeneous agents) or offer higher fidelity with less comparable instrumentation. We present GRACE, a unified 2D simulator+benchmark that instantiates the same task at multiple abstraction levels (grid, roadmap, continuous) via explicit, reproducible operators and a common evaluation protocol. Our empirical results on public maps and representative planners enable commensurate comparisons on a shared instance set. Furthermore, we quantify the expected representation-fidelity trade-offs (MRMP solves instances at higher fidelity but lower speed, while grid/roadmap planners scale farther). By consolidating representation, execution, and evaluation, GRACE thereby aims to make cross-representation studies more comparable and provides a means to advance multi-robot planning research and its translation to practice.