The reliable deployment of deep learning in medical imaging requires uncertainty quantification that provides rigorous error guarantees while remaining anatomically meaningful. Conformal prediction (CP) is a powerful distribution-free framework for constructing statistically valid prediction intervals. However, standard applications in segmentation often ignore anatomical context, resulting in fragmented, spatially incoherent, and over-segmented prediction sets that limit clinical utility. To bridge this gap, this paper proposes Random-Walk Conformal Prediction (RW-CP), a model-agnostic framework which can be added on top of any segmentation method. RW-CP enforces spatial coherence to generate anatomically valid sets. Our method constructs a k-nearest neighbour graph from pre-trained vision foundation model features and applies a random walk to diffuse uncertainty. The random walk diffusion regularizes the non-conformity scores, making the prediction sets less sensitive to the conformal calibration parameter $λ$, ensuring more stable and continuous anatomical boundaries. RW-CP maintains rigorous marginal coverage while significantly improving segmentation quality. Evaluations on multi-modal public datasets show improvements of up to $35.4\%$ compared to standard CP baselines, given an allowable error rate of $α=0.1$.

Reinforcement learning (RL) has emerged as a powerful framework for improving the reasoning capabilities of large language models (LLMs). However, most existing RL approaches rely on sparse outcome rewards, which fail to credit correct intermediate steps in partially successful solutions. Process reward models (PRMs) offer fine-grained step-level supervision, but their scores are often noisy and difficult to evaluate. As a result, recent PRM benchmarks focus on a more objective capability: detecting the first incorrect step in a reasoning path. However, this evaluation target is misaligned with how PRMs are typically used in RL, where their step-wise scores are treated as raw rewards to maximize. To bridge this gap, we propose Verifiable Prefix Policy Optimization (VPPO), which uses PRMs only to localize the first error during RL. Given an incorrect rollout, VPPO partitions the trajectory into a verified correct prefix and an erroneous suffix based on the first error, rewarding the former while applying targeted penalties only after the detected mistake. This design yields stable, interpretable learning signals and improves credit assignment. Across multiple reasoning benchmarks, VPPO consistently outperforms sparse-reward RL and prior PRM-guided baselines on both Pass@1 and Pass@K.

The increasing deployment of Internet-of-Things (IoT)-enabled measurement devices in modern power systems has expanded the cyberattack surface of the grid. As a result, this critical infrastructure is increasingly exposed to cyberattacks, including false data injection attacks (FDIAs) that compromise measurement integrity and threaten reliable system operation. Existing FDIA detection methods primarily exploit spatial correlations and network topology using graph-based learning; however, these approaches often rely on high-dimensional representations and shallow classifiers, limiting their ability to capture local structural dependencies and global contextual relationships. Moreover, naively incorporating Transformer architectures can result in overly deep models that struggle to model localized grid dynamics. This paper proposes a joint FDIA detection and localization framework that integrates auto-regressive moving average (ARMA) graph convolutional filters with an Encoder-Only Transformer architecture. The ARMA-based graph filters provide robust, topology-aware feature extraction and adaptability to abrupt spectral changes, while the Transformer encoder leverages self-attention to capture long-range dependencies among grid elements without sacrificing essential local context. The proposed method is evaluated using real-world load data from the New York Independent System Operator (NYISO) applied to the IEEE 14- and 300-bus systems. Numerical results demonstrate that the proposed model effectively exploits both the state and topology of the power grid, achieving high accuracy in detecting FDIA events and localizing compromised nodes.

Advances in single-cell and spatial transcriptomic technologies have transformed tumor ecosystem profiling at cellular resolution. However, large scale studies on patient cohorts continue to rely on bulk transcriptomic data, where variation in tumor purity obscures tumor-intrinsic transcriptional signals and constrains downstream discovery. Many deconvolution methods report strong performance on synthetic bulk mixtures but fail to generalize to real patient cohorts because of unmodeled biological and technical variation. Here, we introduce TwinPurify, a representation learning framework that adapts the Barlow Twins self-supervised objective, representing a fundamental departure from the deconvolution paradigm. Rather than resolving the bulk mixture into discrete cell-type fractions, TwinPurify instead learns continuous, high-dimensional tumor embeddings by leveraging adjacent-normal profiles within the same cohort as "background" guidance, enabling the disentanglement of tumor-specific signals without relying on any external reference. Benchmarked against multiple large cancer cohorts across RNA-seq and microarray platforms, TwinPurify outperforms conventional representation learning baselines like auto-encoders in recovering tumor-intrinsic and immune signals. The purified embeddings improve molecular subtype and grade classification, enhance survival model concordance, and uncover biologically meaningful pathway activities compared to raw bulk profiles. By providing a transferable framework for decontaminating bulk transcriptomics, TwinPurify extends the utility of existing clinical datasets for molecular discovery.

Motivation: Pathway enrichment analysis is widely used to interpret gene expression data. Standard approaches, such as GSEA, rely on predefined phenotypic labels and pairwise comparisons, which limits their applicability in unsupervised settings. Existing unsupervised extensions, including single-sample methods, provide pathway-level summaries but primarily capture linear relationships and do not explicitly model gene-pathway associations. More recently, deep learning models have been explored to capture non-linear transcriptomic structure. However, their interpretation has typically relied on generic explainable AI (XAI) techniques designed for feature-level attribution. As these methods are not designed for pathway-level interpretation in unsupervised transcriptomic analyses, their effectiveness in this setting remains limited. Results: To bridge this gap, we introduce LaCoGSEA (Latent Correlation GSEA), an unsupervised framework that integrates deep representation learning with robust pathway statistics. LaCoGSEA employs an autoencoder to capture non-linear manifolds and proposes a global gene-latent correlation metric as a proxy for differential expression, generating dense gene rankings without prior labels. We demonstrate that LaCoGSEA offers three key advantages: (i) it achieves improved clustering performance in distinguishing cancer subtypes compared to existing unsupervised baselines; (ii) it recovers a broader range of biologically meaningful pathways at higher ranks compared with linear dimensionality reduction and gradient-based XAI methods; and (iii) it maintains high robustness and consistency across varying experimental protocols and dataset sizes. Overall, LaCoGSEA provides state-of-the-art performance in unsupervised pathway enrichment analysis. Availability and implementation: https://github.com/willyzzz/LaCoGSEA

Mobile manipulators promise agile, long-horizon behavior by coordinating base and arm motion, yet whole-body trajectory optimization in cluttered, confined spaces remains difficult due to high-dimensional nonconvexity and the need for fast, accurate collision reasoning. Configuration Space Distance Fields (CDF) enable fixed-base manipulators to model collisions directly in configuration space via smooth, implicit distances. This representation holds strong potential to bypass the nonlinear configuration-to-workspace mapping while preserving accurate whole-body geometry and providing optimization-friendly collision costs. Yet, extending this capability to mobile manipulators is hindered by unbounded workspaces and tighter base-arm coupling. We lift this promise to mobile manipulation with Generalized Configuration Space Distance Fields (GCDF), extending CDF to robots with both translational and rotational joints in unbounded workspaces with tighter base-arm coupling. We prove that GCDF preserves Euclidean-like local distance structure and accurately encodes whole-body geometry in configuration space, and develop a data generation and training pipeline that yields continuous neural GCDFs with accurate values and gradients, supporting efficient GPU-batched queries. Building on this representation, we develop a high-performance sequential convex optimization framework centered on GCDF-based collision reasoning. The solver scales to large numbers of implicit constraints through (i) online specification of neural constraints, (ii) sparsity-aware active-set detection with parallel batched evaluation across thousands of constraints, and (iii) incremental constraint management for rapid replanning under scene changes.

Structural missingness breaks 'just impute and train': values can be undefined by causal or logical constraints, and the mask may depend on observed variables, unobserved variables (MNAR), and other missingness indicators. It simultaneously brings (i) a catch-22 situation with causal loop, prediction needs the missing features, yet inferring them depends on the missingness mechanism, (ii) under MNAR, the unseen are different, the missing part can come from a shifted distribution, and (iii) plug-in imputation, a single fill-in can lock in uncertainty and yield overconfident, biased decisions. In the Bayesian view, prediction via the posterior predictive distribution integrates over the full model posterior uncertainty, rather than relying on a single point estimate. This framework decouples (i) learning an in-model missing-value posterior from (ii) label prediction by optimizing the predictive posterior distribution, enabling posterior integration. This decoupling yields an in-model almost-free-lunch: once the posterior is learned, prediction is plug-and-play while preserving uncertainty propagation. It achieves SOTA on 43 classification and 15 imputation benchmarks, with finite-sample near Bayes-optimality guarantees under our SCM prior.

Autism spectrum disorder (ASD) represents a neurodevelopmental condition characterized by difficulties in expressing emotions and communication, particularly during early childhood. Understanding the affective state of children at an early age remains challenging, as conventional assessment methods are often intrusive, subjective, or difficult to apply consistently. This paper builds upon previous work on affective state recognition from children's drawings by presenting a comparative evaluation of machine learning models for emotion classification. Three deep learning architectures -- MobileNet, EfficientNet, and VGG16 -- are evaluated within a unified experimental framework to analyze classification performance, robustness, and computational efficiency. The models are trained using transfer learning on a dataset of children's drawings annotated with emotional labels provided by psychological experts. The results highlight important trade-offs between lightweight and deeper architectures when applied to drawing-based affective computing tasks, particularly in mobile and real-time application contexts.

Reconstructing human dynamic visual perception from electroencephalography (EEG) signals is of great research significance since EEG's non-invasiveness and high temporal resolution. However, EEG-to-video reconstruction remains challenging due to: 1) Single Modality: existing studies solely align EEG signals with the text modality, which ignores other modalities and are prone to suffer from overfitting problems; 2) Data Scarcity: current methods often have difficulty training to converge with limited EEG-video data. To solve the above problems, we propose a novel framework MindCine to achieve high-fidelity video reconstructions on limited data. We employ a multimodal joint learning strategy to incorporate beyond-text modalities in the training stage and leverage a pre-trained large EEG model to relieve the data scarcity issue for decoding semantic information, while a Seq2Seq model with causal attention is specifically designed for decoding perceptual information. Extensive experiments demonstrate that our model outperforms state-of-the-art methods both qualitatively and quantitatively. Additionally, the results underscore the effectiveness of the complementary strengths of different modalities and demonstrate that leveraging a large-scale EEG model can further enhance reconstruction performance by alleviating the challenges associated with limited data.

Diffusion Large Language Models (dLLMs) offer a compelling paradigm for natural language generation, leveraging parallel decoding and bidirectional attention to achieve superior global coherence compared to autoregressive models. While recent works have accelerated inference via KV cache reuse or heuristic decoding, they overlook the intrinsic inefficiencies within the block-wise diffusion process. Specifically, they suffer from spatial redundancy by modeling informative-sparse suffix regions uniformly and temporal inefficiency by applying fixed denoising schedules across all the decoding process. To address this, we propose Streaming-dLLM, a training-free framework that streamlines inference across both spatial and temporal dimensions. Spatially, we introduce attenuation guided suffix modeling to approximate the full context by pruning redundant mask tokens. Temporally, we employ a dynamic confidence aware strategy with an early exit mechanism, allowing the model to skip unnecessary iterations for converged tokens. Extensive experiments show that Streaming-dLLM achieves up to 68.2X speedup while maintaining generation quality, highlighting its effectiveness in diffusion decoding. The code is available at https://github.com/xiaoshideta/Streaming-dLLM.

Foundation models for tabular data, such as the Tabular Prior-data Fitted Network (TabPFN), are pre-trained on a massive number of synthetic datasets generated by structural causal models (SCM). They leverage in-context learning to offer high predictive accuracy in real-world tasks. However, the fairness properties of these foundational models, which incorporate ideas from causal reasoning during pre-training, remain underexplored. In this work, we conduct a comprehensive empirical evaluation of TabPFN and its fine-tuned variants, assessing predictive performance, fairness, and robustness across varying dataset sizes and distributional shifts. Our results reveal that while TabPFN achieves stronger predictive accuracy compared to baselines and exhibits robustness to spurious correlations, improvements in fairness are moderate and inconsistent, particularly under missing-not-at-random (MNAR) covariate shifts. These findings suggest that the causal pre-training in TabPFN is helpful but insufficient for algorithmic fairness, highlighting implications for deploying TabPFN (and similar) models in practice and the need for further fairness interventions.

Gaussian Splatting (GS) has demonstrated impressive quality and efficiency in novel view synthesis. However, shape extraction from Gaussian primitives remains an open problem. Due to inadequate geometry parameterization and approximation, existing shape reconstruction methods suffer from poor multi-view consistency and are sensitive to floaters. In this paper, we present a rigorous theoretical derivation that establishes Gaussian primitives as a specific type of stochastic solids. This theoretical framework provides a principled foundation for Geometry-Grounded Gaussian Splatting by enabling the direct treatment of Gaussian primitives as explicit geometric representations. Using the volumetric nature of stochastic solids, our method efficiently renders high-quality depth maps for fine-grained geometry extraction. Experiments show that our method achieves the best shape reconstruction results among all Gaussian Splatting-based methods on public datasets.

Existing Subject-to-Video Generation (S2V) methods have achieved high-fidelity and subject-consistent video generation, yet remain constrained to single-view subject references. This limitation renders the S2V task reducible to an S2I + I2V pipeline, failing to exploit the full potential of video subject control. In this work, we propose and address the challenging Multi-View S2V (MV-S2V) task, which synthesizes videos from multiple reference views to enforce 3D-level subject consistency. Regarding the scarcity of training data, we first develop a synthetic data curation pipeline to generate highly customized synthetic data, complemented by a small-scale real-world captured dataset to boost the training of MV-S2V. Another key issue lies in the potential confusion between cross-subject and cross-view references in conditional generation. To overcome this, we further introduce Temporally Shifted RoPE (TS-RoPE) to distinguish between different subjects and distinct views of the same subject in reference conditioning. Our framework achieves superior 3D subject consistency w.r.t. multi-view reference images and high-quality visual outputs, establishing a new meaningful direction for subject-driven video generation. Our project page is available at: https://szy-young.github.io/mv-s2v

It is widely accepted from transformer research that "attention is all we need", but the amount of attention required has never been systematically quantified. Is quadratic $O(L^2)$ attention necessary, or is there a sub-quadratic attention mechanism that can achieve comparable performance? To answer this question, we introduce power-based partial attention (PPA), an attention mechanism of order $O(L^{1+p})$, where $0 \leq p \leq 1$, such that $p=0$ corresponds to sliding window attention with linear complexity, and $p=1$ corresponds to full attention. With this attention construction, we can explore how transformer architecture performance varies as a function of the attention scaling behavior controlled by $p$. The overall trend from our experiments shows an S-curve-like behavior where the performance transitions from sliding-window (linear-complexity) attention to full attention over a narrow window of $p$ values, and plateaus as $p$ approaches $1$. In our experiments, we show that there exists $0<p<1$ such that $O(L^{1+p})$ attention is sufficient to achieve similar results as $O(L^2)$ full attention.

We revisit benchmarks for differentially private image classification. We suggest a comprehensive set of benchmarks, allowing researchers to evaluate techniques for differentially private machine learning in a variety of settings, including with and without additional data, in convex settings, and on a variety of qualitatively different datasets. We further test established techniques on these benchmarks in order to see which ideas remain effective in different settings. Finally, we create a publicly available leader board for the community to track progress in differentially private machine learning.

The field of image generation is currently bifurcated into autoregressive (AR) models operating on discrete tokens and diffusion models utilizing continuous latents. This divide, rooted in the distinction between VQ-VAEs and VAEs, hinders unified modeling and fair benchmarking. Finite Scalar Quantization (FSQ) offers a theoretical bridge, yet vanilla FSQ suffers from a critical flaw: its equal-interval quantization can cause activation collapse. This mismatch forces a trade-off between reconstruction fidelity and information efficiency. In this work, we resolve this dilemma by simply replacing the activation function in original FSQ with a distribution-matching mapping to enforce a uniform prior. Termed iFSQ, this simple strategy requires just one line of code yet mathematically guarantees both optimal bin utilization and reconstruction precision. Leveraging iFSQ as a controlled benchmark, we uncover two key insights: (1) The optimal equilibrium between discrete and continuous representations lies at approximately 4 bits per dimension. (2) Under identical reconstruction constraints, AR models exhibit rapid initial convergence, whereas diffusion models achieve a superior performance ceiling, suggesting that strict sequential ordering may limit the upper bounds of generation quality. Finally, we extend our analysis by adapting Representation Alignment (REPA) to AR models, yielding LlamaGen-REPA. Codes is available at https://github.com/Tencent-Hunyuan/iFSQ

Venture capital (VC) investments in early-stage startups that end up being successful can yield high returns. However, predicting early-stage startup success remains challenging due to data scarcity (e.g., many VC firms have information about only a few dozen of early-stage startups and whether they were successful). This limits the effectiveness of traditional machine learning methods that rely on large labeled datasets for model training. To address this challenge, we propose an in-context learning framework for startup success prediction using large language models (LLMs) that requires no model training and leverages only a small set of labeled startups as demonstration examples. Specifically, we propose a novel k-nearest-neighbor-based in-context learning framework, called kNN-ICL, which selects the most relevant past startups as examples based on similarity. Using real-world profiles from Crunchbase, we find that the kNN-ICL approach achieves higher prediction accuracy than supervised machine learning baselines and vanilla in-context learning. Further, we study how performance varies with the number of in-context examples and find that a high balanced accuracy can be achieved with as few as 50 examples. Together, we demonstrate that in-context learning can serve as a decision-making tool for VC firms operating in data-scarce environments.

We propose a novel training objective for GPs constructed using lower-dimensional linear projections of the data, referred to as \emph{projected likelihood} (PL). We provide a closed-form expression for the information loss related to the PL and empirically show that it can be reduced with random projections on the unit sphere. We show the superiority of the PL, in terms of accuracy and computational efficiency, over the exact GP training and the variational free energy approach to sparse GPs over different optimisers, kernels and datasets of moderately large sizes.

Edge devices operate in constrained and varying resource settings, requiring dynamic architectures that can adapt to limitations of the available resources. To meet such demands, layer dropping ($\mathcal{LD}$) approach is typically used to transform static models into dynamic ones by skipping parts of the network along with reducing overall computational complexity. However, existing $\mathcal{LD}$ methods greatly impact the dynamic model's performance for low and high dropping cases, deteriorating the performance-computation trade-off. To this end, we propose a distillation-based layer dropping (DLD) framework that effectively combines the capabilities of knowledge distillation and $\mathcal{LD}$ in an end-to-end fashion, thereby achieving state-of-the-art performance for dynamic speech networks. Comprehensive experimentation utilizing well-known speech recognition methods, including conformer and WavLM, on three public benchmarks demonstrates the effectiveness of our framework, reducing the word error rate by $9.32\%$ and $2.25\%$ for high and no dropping cases with $33.3\%$ reduction in training time.

Significant progress has been made in low-light image enhancement with respect to visual quality. However, most existing methods primarily operate in the pixel domain or rely on implicit feature representations. As a result, the intrinsic geometric structural priors of images are often neglected. 2D Gaussian Splatting (2DGS) has emerged as a prominent explicit scene representation technique characterized by superior structural fitting capabilities and high rendering efficiency. Despite these advantages, the utilization of 2DGS in low-level vision tasks remains unexplored. To bridge this gap, LL-GaussianMap is proposed as the first unsupervised framework incorporating 2DGS into low-light image enhancement. Distinct from conventional methodologies, the enhancement task is formulated as a gain map generation process guided by 2DGS primitives. The proposed method comprises two primary stages. First, high-fidelity structural reconstruction is executed utilizing 2DGS. Then, data-driven enhancement dictionary coefficients are rendered via the rasterization mechanism of Gaussian splatting through an innovative unified enhancement module. This design effectively incorporates the structural perception capabilities of 2DGS into gain map generation, thereby preserving edges and suppressing artifacts during enhancement. Additionally, the reliance on paired data is circumvented through unsupervised learning. Experimental results demonstrate that LL-GaussianMap achieves superior enhancement performance with an extremely low storage footprint, highlighting the effectiveness of explicit Gaussian representations for image enhancement.

Tabular data is a fundamental form of data structure. The evolution of table analysis tools reflects humanity's continuous progress in data acquisition, management, and processing. The dynamic changes in table columns arise from technological advancements, changing needs, data integration, etc. However, the standard process of training AI models on tables with fixed columns and then performing inference is not suitable for handling dynamically changed tables. Therefore, new methods are needed for efficiently handling such tables in an unsupervised manner. In this paper, we introduce a new task, Tabular Incremental Inference (TabII), which aims to enable trained models to incorporate new columns during the inference stage, enhancing the practicality of AI models in scenarios where tables are dynamically changed. Furthermore, we demonstrate that this new task can be framed as an optimization problem based on the information bottleneck theory, which emphasizes that the key to an ideal tabular incremental inference approach lies in minimizing mutual information between tabular data and representation while maximizing between representation and task labels. Under this guidance, we design a TabII method with Large Language Model placeholders and Pretrained TabAdapter to provide external knowledge and Incremental Sample Condensation blocks to condense the task-relevant information given by incremental column attributes. Experimental results across eight public datasets show that TabII effectively utilizes incremental attributes, achieving state-of-the-art performance.

Real-world scientific applications frequently encounter incomplete observational data due to sensor limitations, geographic constraints, or measurement costs. Although neural operators significantly advanced PDE solving in terms of computational efficiency and accuracy, their underlying assumption of fully-observed spatial inputs severely restricts applicability in real-world applications. We introduce the first systematic framework for learning neural operators from partial observation. We identify and formalize two fundamental obstacles: (i) the supervision gap in unobserved regions that prevents effective learning of physical correlations, and (ii) the dynamic spatial mismatch between incomplete inputs and complete solution fields. Specifically, our proposed Latent Autoregressive Neural Operator(LANO) introduces two novel components designed explicitly to address the core difficulties of partial observations: (i) a mask-to-predict training strategy that creates artificial supervision by strategically masking observed regions, and (ii) a Physics-Aware Latent Propagator that reconstructs solutions through boundary-first autoregressive generation in latent space. Additionally, we develop POBench-PDE, a dedicated and comprehensive benchmark designed specifically for evaluating neural operators under partial observation conditions across three PDE-governed tasks. LANO achieves state-of-the-art performance with 18--69$\%$ relative L2 error reduction across all benchmarks under patch-wise missingness with less than 50$\%$ missing rate, including real-world climate prediction. Our approach effectively addresses practical scenarios involving up to 75$\%$ missing rate, to some extent bridging the existing gap between idealized research settings and the complexities of real-world scientific computing.

The rapid adoption of LLMs has increased the need for reliable AI text detection, yet existing detectors often fail outside controlled benchmarks. We systematically evaluate 2 dominant paradigms (training-free and supervised) and show that both are brittle under distribution shift, unseen generators, and simple stylistic perturbations. To address these limitations, we propose a supervised contrastive learning (SCL) framework that learns discriminative style embeddings. Experiments show that while supervised detectors excel in-domain, they degrade sharply out-of-domain, and training-free methods remain highly sensitive to proxy choice. Overall, our results expose fundamental challenges in building domain-agnostic detectors. Our code is available at: https://github.com/HARSHITJAIS14/DetectAI

Large language models (LLMs) have demonstrated strong capabilities in knowledge representation and reasoning based on textual data. However, their reliance on language material alone limits their ability to adapt, verify reasoning outcomes, and operate effectively in open and dynamic real-world environments. In this paper, we propose Human Simulation Computation (HSC), a human-inspired computational framework that models intelligence as a continuous, closed-loop process involving thinking, action, learning, reflection, and activity scheduling, collectively referred to as the internal reasoning process. HSC emphasizes active participation both within the internal reasoning process and in interactions with the environment, where actions are used not only to achieve goals but also to automatically refine and improve internal reasoning mechanisms without external intervention. Furthermore, HSC incorporates commonly used human thinking strategies across all stages of the internal reasoning process, such as main-feature-oriented reasoning, scope expansion through action, and on-time learning driven by environmental feedback. Through theoretical analysis, we argue that human simulation strategies cannot be fully learned from language material alone, and that human-like reasoning processes and action-grounded reasoning methods are essential for robust adaptation and effective interaction with real-world environments.

Existing dynamic Theory of Mind (ToM) benchmarks mostly place language models in a passive role: the model reads a sequence of connected scenarios and reports what people believe, feel, intend, and do as these states change. In real social interaction, ToM is also used for action: a speaker plans what to say in order to shift another person's mental-state trajectory toward a goal. We introduce SocialMindChange, a benchmark that moves from tracking minds to changing minds in social interaction. Each instance defines a social context with 4 characters and five connected scenes. The model plays one character and generates dialogue across the five scenes to reach the target while remaining consistent with the evolving states of all participants. SocialMindChange also includes selected higher-order states. Using a structured four-step framework, we construct 1,200 social contexts, covering 6000 scenarios and over 90,000 questions, each validated for realism and quality. Evaluations on ten state-of-the-art LLMs show that their average performance is 54.2% below human performance. This gap suggests that current LLMs still struggle to maintain and change mental-state representations across long, linked interactions.

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding real-time researcher guidance. This paper introduces Deep Research, a multi-agent system enabling interactive scientific investigation with turnaround times measured in minutes. The architecture comprises specialized agents for planning, data analysis, literature search, and novelty detection, unified through a persistent world state that maintains context across iterative research cycles. Two operational modes support different workflows: semi-autonomous mode with selective human checkpoints, and fully autonomous mode for extended investigations. Evaluation on the BixBench computational biology benchmark demonstrated state-of-the-art performance, achieving 48.8% accuracy on open response and 64.4% on multiple-choice evaluation, exceeding existing baselines by 14 to 26 percentage points. Analysis of architectural constraints, including open access literature limitations and challenges inherent to automated novelty assessment, informs practical deployment considerations for AI-assisted scientific workflows.

Efficient fine-tuning of visual-language models like CLIP has become crucial due to their large-scale parameter size and extensive pretraining requirements. Existing methods typically address either the issue of unseen classes or unseen domains in isolation, without considering a joint framework for both. In this paper, we propose \textbf{Fed}erated Joint Learning for \textbf{D}omain and \textbf{C}lass \textbf{G}eneralization, termed \textbf{FedDCG}, a novel approach that addresses both class and domain generalization in federated learning settings. Our method introduces a domain grouping strategy where class-generalized networks are trained within each group to prevent decision boundary confusion. During inference, we aggregate class-generalized results based on domain similarity, effectively integrating knowledge from both class and domain generalization. Specifically, a learnable network is employed to enhance class generalization capabilities, and a decoupling mechanism separates general and domain-specific knowledge, improving generalization to unseen domains. Extensive experiments across various datasets show that \textbf{FedDCG} outperforms state-of-the-art baselines in terms of accuracy and robustness.

Access to mental healthcare is increasingly strained by workforce shortages and rising demand, motivating the development of intelligent systems that can support mental healthcare experts. We introduce coTherapist, a unified framework utilizing a small language model to emulate core therapeutic competencies through domain-specific fine-tuning, retrieval augmentation, and agentic reasoning. Evaluation on clinical queries demonstrates that coTherapist generates more relevant and clinically grounded responses than contemporary baselines. Using our novel T-BARS rubric and psychometric profiling, we confirm coTherapist exhibits high empathy and therapist-consistent personality traits. Furthermore, human evaluation by domain experts validates that coTherapist delivers accurate, trustworthy, and safe responses. coTherapist was deployed and tested by clinical experts. Collectively, these findings demonstrate that small models can be engineered to exhibit expert-like behavior, offering a scalable pathway for digital mental health tools.

This work proposes a contextualised detection framework for implicitly hateful speech, implemented as a multi-agent system comprising a central Moderator Agent and dynamically constructed Community Agents representing specific demographic groups. Our approach explicitly integrates socio-cultural context from publicly available knowledge sources, enabling identity-aware moderation that surpasses state-of-the-art prompting methods (zero-shot prompting, few-shot prompting, chain-of-thought prompting) and alternative approaches on a challenging ToxiGen dataset. We enhance the technical rigour of performance evaluation by incorporating balanced accuracy as a central metric of classification fairness that accounts for the trade-off between true positive and true negative rates. We demonstrate that our community-driven consultative framework significantly improves both classification accuracy and fairness across all target groups.

Point cloud completion aims to recover complete 3D geometry from partial observations caused by limited viewpoints and occlusions. Existing learning-based works, including 3D Convolutional Neural Network (CNN)-based, point-based, and Transformer-based methods, have achieved strong performance on synthetic benchmarks. However, due to the limitations of modality, scalability, and generative capacity, their generalization to novel objects and real-world scenarios remains challenging. In this paper, we propose MGPC, a generalizable multimodal point cloud completion framework that integrates point clouds, RGB images, and text within a unified architecture. MGPC introduces an innovative modality dropout strategy, a Transformer-based fusion module, and a novel progressive generator to improve robustness, scalability, and geometric modeling capability. We further develop an automatic data generation pipeline and construct MGPC-1M, a large-scale benchmark with over 1,000 categories and one million training pairs. Extensive experiments on MGPC-1M and in-the-wild data demonstrate that the proposed method consistently outperforms prior baselines and exhibits strong generalization under real-world conditions.