End-to-end Spoken Language Models (SLMs) hold great potential for paralinguistic perception, and numerous studies have aimed to enhance their capabilities, particularly for empathetic dialogue. However, current approaches largely depend on rigid supervised signals, such as ground-truth response in supervised fine-tuning or preference scores in reinforcement learning. Such reliance is fundamentally limited for modeling complex empathy, as there is no single "correct" response and a simple numerical score cannot fully capture the nuances of emotional expression or the appropriateness of empathetic behavior. To address these limitations, we sequentially introduce EmpathyEval, a descriptive natural-language-based evaluation model for assessing empathetic quality in spoken dialogues. Building upon EmpathyEval, we propose ReEmpathy, an end-to-end SLM that enhances empathetic dialogue through a novel Empathetic Self-Reflective Alternating Inference mechanism, which interleaves spoken response generation with free-form, empathy-related reflective reasoning. Extensive experiments demonstrate that ReEmpathy substantially improves empathy-sensitive spoken dialogue by enabling reflective reasoning, offering a promising approach toward more emotionally intelligent and empathy-aware human-computer interactions.

In many scientific and data-driven applications, machine learning models are increasingly used as measurement instruments, rather than merely as predictors of predefined labels. When the measurement function is learned from data, the mapping from observations to quantities is determined implicitly by the training distribution and inductive biases, allowing multiple inequivalent mappings to satisfy standard predictive evaluation criteria. We formalize learned measurement functions as a distinct focus of evaluation and introduce measurement stability, a property capturing invariance of the measured quantity across admissible realizations of the learning process and across contexts. We show that standard evaluation criteria in machine learning, including generalization error, calibration, and robustness, do not guarantee measurement stability. Through a real-world case study, we show that models with comparable predictive performance can implement systematically inequivalent measurement functions, with distribution shift providing a concrete illustration of this failure. Taken together, our results highlight a limitation of existing evaluation frameworks in settings where learned model outputs are identified as measurements, motivating the need for an additional evaluative dimension.

Universal approximation theory offers a foundational framework to verify neural network expressiveness, enabling principled utilization in real-world applications. However, most existing theoretical constructions are established by uniformly dividing the input space into tiny hypercubes without considering the local regularity of the target function. In this work, we investigate the universal approximation capabilities of ReLU networks from a view of polytope decomposition, which offers a more realistic and task-oriented approach compared to current methods. To achieve this, we develop an explicit kernel polynomial method to derive an universal approximation of continuous functions, which is characterized not only by the refined Totik-Ditzian-type modulus of continuity, but also by polytopical domain decomposition. Then, a ReLU network is constructed to approximate the kernel polynomial in each subdomain separately. Furthermore, we find that polytope decomposition makes our approximation more efficient and flexible than existing methods in many cases, especially near singular points of the objective function. Lastly, we extend our approach to analytic functions to reach a higher approximation rate.

Aerial images play a vital role in urban planning and environmental preservation, as they consist of various structures, representing different types of buildings, forests, mountains, and unoccupied lands. Due to its heterogeneous nature, developing robust models for scene classification remains a challenge. In this study, we conduct a literature review of various machine learning methods for aerial image classification. Our survey covers a range of approaches from handcrafted features (e.g., SIFT, LBP) to traditional CNNs (e.g., VGG, GoogLeNet), and advanced deep hybrid networks. In this connection, we have also designed Aerial-Y-Net, a spatial attention-enhanced CNN with multi-scale feature fusion mechanism, which acts as an attention-based model and helps us to better understand the complexities of aerial images. Evaluated on the AID dataset, our model achieves 91.72% accuracy, outperforming several baseline architectures.

Catastrophic forgetting impairs the continuous learning of large language models. We propose Fisher-Guided Gradient Masking (FGGM), a framework that mitigates this by strategically selecting parameters for updates using diagonal Fisher Information. FGGM dynamically generates binary masks with adaptive thresholds, preserving critical parameters to balance stability and plasticity without requiring historical data. Unlike magnitude-based methods such as MIGU, our approach offers a mathematically principled parameter importance estimation. On the TRACE benchmark, FGGM shows a 9.6% relative improvement in retaining general capabilities over supervised fine-tuning (SFT) and a 4.4% improvement over MIGU on TRACE tasks. Additional analysis on code generation tasks confirms FGGM's superior performance and reduced forgetting, establishing it as an effective solution.

Continual learning in Large Language Models (LLMs) faces the critical challenge of balancing stability (retaining old knowledge) and plasticity (learning new tasks). While Experience Replay (ER) is a standard countermeasure against catastrophic forgetting, its impact across diverse capabilities remains underexplored. In this work, we uncover a critical dichotomy in ER's behavior: while it induces positive backward transfer on robust, unstructured tasks (e.g., boosting performance on previous NLP classification tasks through repeated rehearsal), it causes severe negative transfer on fragile, structured domains like code generation (e.g., a significant relative drop in coding accuracy). This reveals that ER trades structural integrity for broad consolidation. To address this dilemma, we propose \textbf{Orthogonal Subspace Wake-up (OSW)}. OSW identifies essential parameter subspaces of previous tasks via a brief "wake-up" phase and enforces orthogonal updates for new tasks, providing a mathematically grounded "safety guarantee" for established knowledge structures. Empirical results across a diverse four-task sequence demonstrate that OSW uniquely succeeds in preserving fragile coding abilities where Replay fails, while simultaneously maintaining high plasticity for novel tasks. Our findings emphasize the necessity of evaluating structural safety alongside average retention in LLM continual learning.

Accurate evaluation of user satisfaction is critical for iterative development of conversational AI. However, for open-ended assistants, traditional A/B testing lacks reliable metrics: explicit feedback is sparse, while implicit metrics are ambiguous. To bridge this gap, we introduce BoRP (Bootstrapped Regression Probing), a scalable framework for high-fidelity satisfaction evaluation. Unlike generative approaches, BoRP leverages the geometric properties of LLM latent space. It employs a polarization-index-based bootstrapping mechanism to automate rubric generation and utilizes Partial Least Squares (PLS) to map hidden states to continuous scores. Experiments on industrial datasets show that BoRP (Qwen3-8B/14B) significantly outperforms generative baselines (even Qwen3-Max) in alignment with human judgments. Furthermore, BoRP reduces inference costs by orders of magnitude, enabling full-scale monitoring and highly sensitive A/B testing via CUPED.

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on task-specific, supervised learning paradigms. These methods are inherently fragmented, require extensive annotated datasets, and often lack generalizability across different modalities and clinical scenarios. The development of foundation models in this field has been constrained by the scarcity of large-scale, curated, and open-source musculoskeletal datasets. To address these challenges, we introduce OrthoFoundation, a multimodal vision foundation model optimized for musculoskeletal pathology. We constructed a pre-training dataset of 1.2 million unlabeled knee X-ray and MRI images from internal and public databases. Utilizing a Dinov3 backbone, the model was trained via self-supervised contrastive learning to capture robust radiological representations. OrthoFoundation achieves state-of-the-art (SOTA) performance across 14 downstream tasks. It attained superior accuracy in X-ray osteoarthritis diagnosis and ranked first in MRI structural injury detection. The model demonstrated remarkable label efficiency, matching supervised baselines using only 50% of labeled data. Furthermore, despite being pre-trained on knee images, OrthoFoundation exhibited exceptional cross-anatomy generalization to the hip, shoulder, and ankle. OrthoFoundation represents a significant advancement toward general-purpose AI for musculoskeletal imaging. By learning fundamental, joint-agnostic radiological semantics from large-scale multimodal data, it overcomes the limitations of conventional models, which provides a robust framework for reducing annotation burdens and enhancing diagnostic accuracy in clinical practice.

Multimodal Large Language Models (MLLMs) have shown remarkable capability in assisting disease diagnosis in medical visual question answering (VQA). However, their outputs remain vulnerable to hallucinations (i.e., responses that contradict visual facts), posing significant risks in high-stakes medical scenarios. Recent introspective detection methods, particularly uncertainty-based approaches, offer computational efficiency but are fundamentally indirect, as they estimate predictive uncertainty for an image-question pair rather than verifying the factual correctness of a specific answer. To address this limitation, we propose Visual Logical Loop Verification (V-Loop), a training-free and plug-and-play framework for hallucination detection in medical VQA. V-Loop introduces a bidirectional reasoning process that forms a visually grounded logical loop to verify factual correctness. Given an input, the MLLM produces an answer for the primary input pair. V-Loop extracts semantic units from the primary QA pair, generates a verification question by conditioning on the answer unit to re-query the question unit, and enforces visual attention consistency to ensure answering both primary question and verification question rely on the same image evidence. If the verification answer matches the expected semantic content, the logical loop closes, indicating factual grounding; otherwise, the primary answer is flagged as hallucinated. Extensive experiments on multiple medical VQA benchmarks and MLLMs show that V-Loop consistently outperforms existing introspective methods, remains highly efficient, and further boosts uncertainty-based approaches when used in combination.

Professionals working in technical domain typically hand-draw (on whiteboard, paper, etc.) technical diagrams (e.g., flowcharts, block diagrams, etc.) during discussions; however, if they want to edit these later, it needs to be drawn from scratch. Modern day VLMs have made tremendous progress in image understanding but they struggle when it comes to understanding technical diagrams. One way to overcome this problem is to fine-tune on real world hand-drawn images, but it is not practically possible to generate large number of such images. In this paper, we introduce a large synthetically generated corpus (reflective of real world images) for training VLMs and subsequently evaluate VLMs on a smaller corpus of hand-drawn images (with the help of humans). We introduce several new self-supervision tasks for training and perform extensive experiments with various baseline models and fine-tune Llama 3.2 11B-instruct model on synthetic images on these tasks to obtain LLama-VL-TUG, which significantly improves the ROUGE-L performance of Llama 3.2 11B-instruct by 2.14x and achieves the best all-round performance across all baseline models. On real-world images, human evaluation reveals that we achieve minimum compilation errors across all baselines in 7 out of 8 diagram types and improve the average F1 score of Llama 3.2 11B-instruct by 6.97x.

Detection of human emotions based on facial images in real-world scenarios is a difficult task due to low image quality, variations in lighting, pose changes, background distractions, small inter-class variations, noisy crowd-sourced labels, and severe class imbalance, as observed in the FER-2013 dataset of 48x48 grayscale images. Although recent approaches using large CNNs such as VGG and ResNet achieve reasonable accuracy, they are computationally expensive and memory-intensive, limiting their practicality for real-time applications. We address these challenges using a lightweight and efficient facial emotion recognition pipeline based on EfficientNetB2, trained using a two-stage warm-up and fine-tuning strategy. The model is enhanced with AdamW optimization, decoupled weight decay, label smoothing (epsilon = 0.06) to reduce annotation noise, and clipped class weights to mitigate class imbalance, along with dropout, mixed-precision training, and extensive real-time data augmentation. The model is trained using a stratified 87.5%/12.5% train-validation split while keeping the official test set intact, achieving a test accuracy of 68.78% with nearly ten times fewer parameters than VGG16-based baselines. Experimental results, including per-class metrics and learning dynamics, demonstrate stable training and strong generalization, making the proposed approach suitable for real-time and edge-based applications.

Large language model (LLM)-based agents are increasingly deployed in e-commerce shopping. To perform thorough, user-tailored product searches, agents should interpret personal preferences, engage in multi-turn dialogues, and ultimately retrieve and discriminate among highly similar products. However, existing research has yet to provide a unified simulation environment that consistently captures all of these aspects, and always focuses solely on evaluation benchmarks without training support. In this paper, we introduce ShopSimulator, a large-scale and challenging Chinese shopping environment. Leveraging ShopSimulator, we evaluate LLMs across diverse scenarios, finding that even the best-performing models achieve less than 40% full-success rate. Error analysis reveals that agents struggle with deep search and product selection in long trajectories, fail to balance the use of personalization cues, and to effectively engage with users. Further training exploration provides practical guidance for overcoming these weaknesses, with the combination of supervised fine-tuning (SFT) and reinforcement learning (RL) yielding significant performance improvements. Code and data will be released at https://github.com/ShopAgent-Team/ShopSimulator.

Deep homography estimation has broad applications in computer vision and robotics. Remarkable progresses have been achieved while the existing methods typically treat it as a direct regression or iterative refinement problem and often struggling to capture complex geometric transformations or generalize across different domains. In this work, we propose HomoFM, a new framework that introduces the flow matching technique from generative modeling into the homography estimation task for the first time. Unlike the existing methods, we formulate homography estimation problem as a velocity field learning problem. By modeling a continuous and point-wise velocity field that transforms noisy distributions into registered coordinates, the proposed network recovers high-precision transformations through a conditional flow trajectory. Furthermore, to address the challenge of domain shifts issue, e.g., the cases of multimodal matching or varying illumination scenarios, we integrate a gradient reversal layer (GRL) into the feature extraction backbone. This domain adaptation strategy explicitly constrains the encoder to learn domain-invariant representations, significantly enhancing the network's robustness. Extensive experiments demonstrate the effectiveness of the proposed method, showing that HomoFM outperforms state-of-the-art methods in both estimation accuracy and robustness on standard benchmarks. Code and data resource are available at https://github.com/hmf21/HomoFM.

Generalist LLM agents are often post-trained on a narrow set of environments but deployed across far broader, unseen domains. In this work, we investigate the challenge of agentic post-training when the eventual test domains are unknown. Specifically, we analyze which properties of reinforcement learning (RL) environments and modeling choices have the greatest influence on out-of-domain performance. First, we identify two environment axes that strongly correlate with cross-domain generalization: (i) state information richness, i.e., the amount of information for the agent to process from the state, and (ii) planning complexity, estimated via goal reachability and trajectory length under a base policy. Notably, domain realism and text-level similarity are not the primary factors; for instance, the simple grid-world domain Sokoban leads to even stronger generalization in SciWorld than the more realistic ALFWorld. Motivated by these findings, we further show that increasing state information richness alone can already effectively improve cross-domain robustness. We propose a randomization technique, which is low-overhead and broadly applicable: add small amounts of distractive goal-irrelevant features to the state to make it richer without altering the task. Beyond environment-side properties, we also examine several modeling choices: (a) SFT warmup or mid-training helps prevent catastrophic forgetting during RL but undermines generalization to domains that are not included in the mid-training datamix; and (b) turning on step-by-step thinking during RL, while not always improving in-domain performance, plays a crucial role in preserving generalization.

Search agents are language models (LMs) that reason and search knowledge bases (or the web) to answer questions; recent methods supervise only the final answer accuracy using reinforcement learning with verifiable rewards (RLVR). Most RLVR search agents tackle general-domain QA, which limits their relevance to technical AI systems in science, engineering, and medicine. In this work we propose training agents to search and reason over scientific papers -- this tests technical question-answering, it is directly relevant to real scientists, and the capabilities will be crucial to future AI Scientist systems. Concretely, we release a search corpus of 16 million biomedical paper abstracts and construct a challenging factoid QA dataset called PaperSearchQA with 60k samples answerable from the corpus, along with benchmarks. We train search agents in this environment to outperform non-RL retrieval baselines; we also perform further quantitative analysis and observe interesting agent behaviors like planning, reasoning, and self-verification. Our corpus, datasets, and benchmarks are usable with the popular Search-R1 codebase for RLVR training and released on https://huggingface.co/collections/jmhb/papersearchqa. Finally, our data creation methods are scalable and easily extendable to other scientific domains.

Large language model-based agents operating in long-horizon interactions require memory systems that support temporal consistency, multi-hop reasoning, and evidence-grounded reuse across sessions. Existing approaches largely rely on unstructured retrieval or coarse abstractions, which often lead to temporal conflicts, brittle reasoning, and limited traceability. We propose MemWeaver, a unified memory framework that consolidates long-term agent experiences into three interconnected components: a temporally grounded graph memory for structured relational reasoning, an experience memory that abstracts recurring interaction patterns from repeated observations, and a passage memory that preserves original textual evidence. MemWeaver employs a dual-channel retrieval strategy that jointly retrieves structured knowledge and supporting evidence to construct compact yet information-dense contexts for reasoning. Experiments on the LoCoMo benchmark demonstrate that MemWeaver substantially improves multi-hop and temporal reasoning accuracy while reducing input context length by over 95\% compared to long-context baselines.

Deep search agents, which aim to answer complex questions requiring reasoning across multiple documents, can significantly speed up the information-seeking process. Collecting human annotations for this application is prohibitively expensive due to long and complex exploration trajectories. We propose an agentic pipeline that automatically generates high quality, difficulty-controlled deep search question-answer pairs for a given corpus and a target difficulty level. Our pipeline, SAGE, consists of a data generator which proposes QA pairs and a search agent which attempts to solve the generated question and provide execution feedback for the data generator. The two components interact over multiple rounds to iteratively refine the question-answer pairs until they satisfy the target difficulty level. Our intrinsic evaluation shows SAGE generates questions that require diverse reasoning strategies, while significantly increases the correctness and difficulty of the generated data. Our extrinsic evaluation demonstrates up to 23% relative performance gain on popular deep search benchmarks by training deep search agents with our synthetic data. Additional experiments show that agents trained on our data can adapt from fixed-corpus retrieval to Google Search at inference time, without further training.

Wireless foundation models promise transformative capabilities for channel state information (CSI) processing across diverse 6G network applications, yet face fundamental challenges due to the inherent dual heterogeneity of CSI across both scale and scenario dimensions. However, current pretraining approaches either constrain inputs to fixed dimensions or isolate training by scale, limiting the generalization and scalability of wireless foundation models. In this paper, we propose HeterCSI, a channel-adaptive pretraining framework that reconciles training efficiency with robust cross-scenario generalization via a new understanding of gradient dynamics in heterogeneous CSI pretraining. Our key insight reveals that CSI scale heterogeneity primarily causes destructive gradient interference, while scenario diversity actually promotes constructive gradient alignment when properly managed. Specifically, we formulate heterogeneous CSI batch construction as a partitioning optimization problem that minimizes zero-padding overhead while preserving scenario diversity. To solve this, we develop a scale-aware adaptive batching strategy that aligns CSI samples of similar scales, and design a double-masking mechanism to isolate valid signals from padding artifacts. Extensive experiments on 12 datasets demonstrate that HeterCSI establishes a generalized foundation model without scenario-specific finetuning, achieving superior average performance over full-shot baselines. Compared to the state-of-the-art zero-shot benchmark WiFo, it reduces NMSE by 7.19 dB, 4.08 dB, and 5.27 dB for CSI reconstruction, time-domain, and frequency-domain prediction, respectively. The proposed HeterCSI framework also reduces training latency by 53% compared to existing approaches while improving generalization performance by 1.53 dB on average.

While Large Vision-Language Models (LVLMs) have significantly advanced GUI agents' capabilities in parsing textual instructions, interpreting screen content, and executing tasks, a critical challenge persists: the irreversibility of agent operations, where a single erroneous action can trigger catastrophic deviations. To address this, we propose the GUI Action Critic's Data Flywheel System (GAIA), a training framework that enables the models to have iterative critic capabilities, which are used to improve the Test-Time Scaling (TTS) of basic GUI agents' performance. Specifically, we train an Intuitive Critic Model (ICM) using positive and negative action examples from a base agent first. This critic evaluates the immediate correctness of the agent's intended actions, thereby selecting operations with higher success probability. Then, the initial critic guides agent actions to collect refined positive/negative samples, initiating the self-improving cycle. The augmented data then trains a second-round critic with enhanced discernment capability. We conduct experiments on various datasets and demonstrate that the proposed ICM can improve the test-time performance of various closed-source and open-source models, and the performance can be gradually improved as the data is recycled. The code and dataset will be publicly released.

Visual quality assessment (VQA) is increasingly shifting from scalar score prediction toward interpretable quality understanding -- a paradigm that demands \textit{fine-grained spatiotemporal perception} and \textit{auxiliary contextual information}. Current approaches rely on supervised fine-tuning or reinforcement learning on curated instruction datasets, which involve labor-intensive annotation and are prone to dataset-specific biases. To address these challenges, we propose \textbf{QualiRAG}, a \textit{training-free} \textbf{R}etrieval-\textbf{A}ugmented \textbf{G}eneration \textbf{(RAG)} framework that systematically leverages the latent perceptual knowledge of large multimodal models (LMMs) for visual quality perception. Unlike conventional RAG that retrieves from static corpora, QualiRAG dynamically generates auxiliary knowledge by decomposing questions into structured requests and constructing four complementary knowledge sources: \textit{visual metadata}, \textit{subject localization}, \textit{global quality summaries}, and \textit{local quality descriptions}, followed by relevance-aware retrieval for evidence-grounded reasoning. Extensive experiments show that QualiRAG achieves substantial improvements over open-source general-purpose LMMs and VQA-finetuned LMMs on visual quality understanding tasks, and delivers competitive performance on visual quality comparison tasks, demonstrating robust quality assessment capabilities without any task-specific training. The code will be publicly available at https://github.com/clh124/QualiRAG.

Vision-Language Pre-training (VLP) models like CLIP have significantly advanced Remote Sensing Image-Text Retrieval (RSITR). However, existing methods predominantly rely on coarse-grained global alignment, which often overlooks the dense, multi-scale semantics inherent in overhead imagery. Moreover, adapting these heavy models via full fine-tuning incurs prohibitive computational costs and risks catastrophic forgetting. To address these challenges, we propose MPS-CLIP, a parameter-efficient framework designed to shift the retrieval paradigm from global matching to keyword-guided fine-grained alignment. Specifically, we leverage a Large Language Model (LLM) to extract core semantic keywords, guiding the Segment Anything Model (SamGeo) to generate semantically relevant sub-perspectives. To efficiently adapt the frozen backbone, we introduce a Gated Global Attention (G^2A) adapter, which captures global context and long-range dependencies with minimal overhead. Furthermore, a Multi-Perspective Representation (MPR) module aggregates these local cues into robust multi-perspective embeddings. The framework is optimized via a hybrid objective combining multi-perspective contrastive and weighted triplet losses, which dynamically selects maximum-response perspectives to suppress noise and enforce precise semantic matching. Extensive experiments on the RSICD and RSITMD benchmarks demonstrate that MPS-CLIP achieves state-of-the-art performance with 35.18% and 48.40% mean Recall (mR), respectively, significantly outperforming full fine-tuning baselines and recent competitive methods. Code is available at https://github.com/Lcrucial1f/MPS-CLIP.

Continuous optimization has significantly advanced causal discovery, yet existing methods (e.g., NOTEARS) generally guarantee only asymptotic convergence to a stationary point. This often yields dense weighted matrices that require arbitrary post-hoc thresholding to recover a DAG. This gap between continuous optimization and discrete graph structures remains a fundamental challenge. In this paper, we bridge this gap by proposing the Hybrid-Order Acyclicity Constraint (AHOC) and optimizing it via the Smoothed Proximal Gradient (SPG-AHOC). Leveraging the Manifold Identification Property of proximal algorithms, we provide a rigorous theoretical guarantee: the Finite-Time Oracle Property. We prove that under standard identifiability assumptions, SPG-AHOC recovers the exact DAG support (structure) in finite iterations, even when optimizing a smoothed approximation. This result eliminates structural ambiguity, as our algorithm returns graphs with exact zero entries without heuristic truncation. Empirically, SPG-AHOC achieves state-of-the-art accuracy and strongly corroborates the finite-time identification theory.

One-stage object detection, particularly the YOLO series, strikes a favorable balance between accuracy and efficiency. However, existing YOLO detectors lack explicit modeling of heterogeneous object responses within shared feature channels, which limits further performance gains. To address this, we propose YOLO-DS, a framework built around a novel Dual-Statistic Synergy Operator (DSO). The DSO decouples object features by jointly modeling the channel-wise mean and the peak-to-mean difference. Building upon the DSO, we design two lightweight gating modules: the Dual-Statistic Synergy Gating (DSG) module for adaptive channel-wise feature selection, and the Multi-Path Segmented Gating (MSG) module for depth-wise feature weighting. On the MS-COCO benchmark, YOLO-DS consistently outperforms YOLOv8 across five model scales (N, S, M, L, X), achieving AP gains of 1.1% to 1.7% with only a minimal increase in inference latency. Extensive visualization, ablation, and comparative studies validate the effectiveness of our approach, demonstrating its superior capability in discriminating heterogeneous objects with high efficiency.

Unsupervised Domain Adaptation (UDA) aims to mitigate performance degradation when training and testing data are sampled from different distributions. While significant progress has been made in enhancing overall accuracy, most existing methods overlook performance disparities across categories-an issue we refer to as category fairness. Our empirical analysis reveals that UDA classifiers tend to favor certain easy categories while neglecting difficult ones. To address this, we propose Virtual Label-distribution-aware Learning (VILL), a simple yet effective framework designed to improve worst-case performance while preserving high overall accuracy. The core of VILL is an adaptive re-weighting strategy that amplifies the influence of hard-to-classify categories. Furthermore, we introduce a KL-divergence-based re-balancing strategy, which explicitly adjusts decision boundaries to enhance category fairness. Experiments on commonly used datasets demonstrate that VILL can be seamlessly integrated as a plug-and-play module into existing UDA methods, significantly improving category fairness.

Transarterial chemoembolization (TACE) is a preferred treatment option for hepatocellular carcinoma and other liver malignancies, yet it remains a highly challenging procedure due to complex intra-operative vascular navigation and anatomical variability. Accurate and robust 2D-3D vessel registration is essential to guide microcatheter and instruments during TACE, enabling precise localization of vascular structures and optimal therapeutic targeting. To tackle this issue, we develop a coarse-to-fine registration strategy. First, we introduce a global alignment module, structure-aware perspective n-point (SA-PnP), to establish correspondence between 2D and 3D vessel structures. Second, we propose TempDiffReg, a temporal diffusion model that performs vessel deformation iteratively by leveraging temporal context to capture complex anatomical variations and local structural changes. We collected data from 23 patients and constructed 626 paired multi-frame samples for comprehensive evaluation. Experimental results demonstrate that the proposed method consistently outperforms state-of-the-art (SOTA) methods in both accuracy and anatomical plausibility. Specifically, our method achieves a mean squared error (MSE) of 0.63 mm and a mean absolute error (MAE) of 0.51 mm in registration accuracy, representing 66.7\% lower MSE and 17.7\% lower MAE compared to the most competitive existing approaches. It has the potential to assist less-experienced clinicians in safely and efficiently performing complex TACE procedures, ultimately enhancing both surgical outcomes and patient care. Code and data are available at: \textcolor{blue}{https://github.com/LZH970328/TempDiffReg.git}

Fine-grained emotion recognition is a challenging multi-label NLP task due to label overlap and class imbalance. In this work, we benchmark three modeling families on the GoEmotions dataset: a TF-IDF-based logistic regression system trained with binary relevance, a BiLSTM with attention, and a BERT model fine-tuned for multi-label classification. Experiments follow the official train/validation/test split, and imbalance is mitigated using inverse-frequency class weights. Across several metrics, namely Micro-F1, Macro-F1, Hamming Loss, and Subset Accuracy, we observe that logistic regression attains the highest Micro-F1 of 0.51, while BERT achieves the best overall balance surpassing the official paper's reported results, reaching Macro-F1 0.49, Hamming Loss 0.036, and Subset Accuracy 0.36. This suggests that frequent emotions often rely on surface lexical cues, whereas contextual representations improve performance on rarer emotions and more ambiguous examples.

Safe reinforcement learning (Safe RL) seeks to maximize rewards while satisfying safety constraints, typically addressed through Lagrangian-based methods. However, existing approaches, including PID and classical Lagrangian methods, suffer from oscillations and frequent safety violations due to parameter sensitivity and inherent phase lag. To address these limitations, we propose ADRC-Lagrangian methods that leverage Active Disturbance Rejection Control (ADRC) for enhanced robustness and reduced oscillations. Our unified framework encompasses classical and PID Lagrangian methods as special cases while significantly improving safety performance. Extensive experiments demonstrate that our approach reduces safety violations by up to 74%, constraint violation magnitudes by 89%, and average costs by 67\%, establishing superior effectiveness for Safe RL in complex environments.

While agent evaluation has shifted toward long-horizon tasks, most benchmarks still emphasize local, step-level reasoning rather than the global constrained optimization (e.g., time and financial budgets) that demands genuine planning ability. Meanwhile, existing LLM planning benchmarks underrepresent the active information gathering and fine-grained local constraints typical of real-world settings. To address this, we introduce DeepPlanning, a challenging benchmark for practical long-horizon agent planning. It features multi-day travel planning and multi-product shopping tasks that require proactive information acquisition, local constrained reasoning, and global constrained optimization. Evaluations on DeepPlanning show that even frontier agentic LLMs struggle with these problems, highlighting the importance of reliable explicit reasoning patterns and parallel tool use for achieving better effectiveness-efficiency trade-offs. Error analysis further points to promising directions for improving agentic LLMs over long planning horizons. We open-source the code and data to support future research.

Missed and delayed diagnosis remains a major challenge in rare disease care. At the initial clinical encounters, physicians assess rare disease risk using only limited information under high uncertainty. When high-risk patients are not recognised at this stage, targeted diagnostic testing is often not initiated, resulting in missed diagnosis. Existing primary care triage processes are structurally insufficient to reliably identify patients with rare diseases at initial clinical presentation and universal screening is needed to reduce diagnostic delay. Here we present RareAlert, an early screening system which predict patient-level rare disease risk from routinely available primary-visit information. RareAlert integrates reasoning generated by ten LLMs, calibrates and weights these signals using machine learning, and distils the aligned reasoning into a single locally deployable model. To develop and evaluate RareAlert, we curated RareBench, a real-world dataset of 158,666 cases covering 33 Orphanet disease categories and more than 7,000 rare conditions, including both rare and non-rare presentations. The results showed that rare disease identification can be reconceptualised as a universal uncertainty resolution process applied to the general patient population. On an independent test set, RareAlert, a Qwen3-4B based model trained with calibrated reasoning signals, achieved an AUC of 0.917, outperforming the best machine learning ensemble and all evaluated LLMs, including GPT-5, DeepSeek-R1, Claude-3.7-Sonnet, o3-mini, Gemini-2.5-Pro, and Qwen3-235B. These findings demonstrate the diversity in LLM medical reasoning and the effectiveness of aligning such reasoning in highly uncertain clinical tasks. By incorporating calibrated reasoning into a single model, RareAlert enables accurate, privacy-preserving, and scalable rare disease risk screening suitable for large-scale local deployment.

Mixture-of-Agents (MoA) improves LLM performance through layered collaboration, but its dense topology raises costs and latency. Existing methods employ LLM judges to filter responses, yet still require all models to perform inference before judging, failing to cut costs effectively. They also lack model selection criteria and struggle with large model pools, where full inference is costly and can exceed context limits. To address this, we propose RouteMoA, an efficient mixture-of-agents framework with dynamic routing. It employs a lightweight scorer to perform initial screening by predicting coarse-grained performance from the query, narrowing candidates to a high-potential subset without inference. A mixture of judges then refines these scores through lightweight self- and cross-assessment based on existing model outputs, providing posterior correction without additional inference. Finally, a model ranking mechanism selects models by balancing performance, cost, and latency. RouteMoA outperforms MoA across varying tasks and model pool sizes, reducing cost by 89.8% and latency by 63.6% in the large-scale model pool.