In this paper, we introduce an Adaptive Graph Signal Processing with Dynamic Semantic Alignment (AGSP DSA) framework to perform robust multimodal data fusion over heterogeneous sources, including text, audio, and images. The requested approach uses a dual-graph construction to learn both intra-modal and inter-modal relations, spectral graph filtering to boost the informative signals, and effective node embedding with Multi-scale Graph Convolutional Networks (GCNs). Semantic aware attention mechanism: each modality may dynamically contribute to the context with respect to contextual relevance. The experimental outcomes on three benchmark datasets, including CMU-MOSEI, AVE, and MM-IMDB, show that AGSP-DSA performs as the state of the art. More precisely, it achieves 95.3% accuracy, 0.936 F1-score, and 0.924 mAP on CMU-MOSEI, improving MM-GNN by 2.6 percent in accuracy. It gets 93.4% accuracy and 0.911 F1-score on AVE and 91.8% accuracy and 0.886 F1-score on MM-IMDB, which demonstrate good generalization and robustness in the missing modality setting. These findings verify the efficiency of AGSP-DSA in promoting multimodal learning in sentiment analysis, event recognition and multimedia classification.

Climate change is expected to intensify rainfall and other hazards, increasing disruptions in urban transportation systems. Designing effective adaptation strategies is challenging due to the long-term, sequential nature of infrastructure investments, deep uncertainty, and complex cross-sector interactions. We propose a generic decision-support framework that couples an integrated assessment model (IAM) with reinforcement learning (RL) to learn adaptive, multi-decade investment pathways under uncertainty. The framework combines long-term climate projections (e.g., IPCC scenario pathways) with models that map projected extreme-weather drivers (e.g. rain) into hazard likelihoods (e.g. flooding), propagate hazards into urban infrastructure impacts (e.g. transport disruption), and value direct and indirect consequences for service performance and societal costs. Embedded in a reinforcement-learning loop, it learns adaptive climate adaptation policies that trade off investment and maintenance expenditures against avoided impacts. In collaboration with Copenhagen Municipality, we demonstrate the approach on pluvial flooding in the inner city for the horizon of 2024 to 2100. The learned strategies yield coordinated spatial-temporal pathways and improved robustness relative to conventional optimization baselines, namely inaction and random action, illustrating the framework's transferability to other hazards and cities.

Personality detection aims to measure an individual's corresponding personality traits through their social media posts. The advancements in Large Language Models (LLMs) offer novel perspectives for personality detection tasks. Existing approaches enhance personality trait analysis by leveraging LLMs to extract semantic information from textual posts as prompts, followed by training classifiers for categorization. However, accurately classifying personality traits remains challenging due to the inherent complexity of human personality and subtle inter-trait distinctions. Moreover, prompt-based methods often exhibit excessive dependency on expert-crafted knowledge without autonomous pattern-learning capacity. To address these limitations, we view personality detection as a ranking task rather than a classification and propose a corresponding reinforcement learning training paradigm. First, we employ supervised fine-tuning (SFT) to establish personality trait ranking capabilities while enforcing standardized output formats, creating a robust initialization. Subsequently, we introduce Group Relative Policy Optimization (GRPO) with a specialized ranking-based reward function. Unlike verification tasks with definitive solutions, personality assessment involves subjective interpretations and blurred boundaries between trait categories. Our reward function explicitly addresses this challenge by training LLMs to learn optimal answer rankings. Comprehensive experiments have demonstrated that our method achieves state-of-the-art performance across multiple personality detection benchmarks.

Parallelization in Reinforcement Learning is typically employed to speed up the training of a single policy, where multiple workers collect experience from an identical sampling distribution. This common design limits the potential of parallelization by neglecting the advantages of diverse exploration strategies. We propose K-Myriad, a scalable and unsupervised method that maximizes the collective state entropy induced by a population of parallel policies. By cultivating a portfolio of specialized exploration strategies, K-Myriad provides a robust initialization for Reinforcement Learning, leading to both higher training efficiency and the discovery of heterogeneous solutions. Experiments on high-dimensional continuous control tasks, with large-scale parallelization, demonstrate that K-Myriad can learn a broad set of distinct policies, highlighting its effectiveness for collective exploration and paving the way towards novel parallelization strategies.

We propose a tensor-based domain alignment (DA) algorithm designed to align source and target tensors within an invariant subspace through the use of alignment matrices. These matrices along with the subspace undergo iterative optimization of which constraint is on oblique manifold, which offers greater flexibility and adaptability compared to the traditional Stiefel manifold. Moreover, regularization terms defined to preserve the variance of both source and target tensors, ensures robust performance. Our framework is versatile, effectively generalizing existing tensor-based DA methods as special cases. Through extensive experiments, we demonstrate that our approach not only enhances DA conversion speed but also significantly boosts classification accuracy. This positions our method as superior to current state-of-the-art techniques, making it a preferable choice for complex domain adaptation tasks.

As the important component of the Earth observation system, hyperspectral imaging satellites provide high-fidelity and enriched information for the formulation of related policies due to the powerful spectral measurement capabilities. However, the transmission speed of the satellite downlink has become a major bottleneck in certain applications, such as disaster monitoring and emergency mapping, which demand a fast response ability. We propose an efficient AI-enabled Satellite Edge Computing paradigm for hyperspectral image classification, facilitating the satellites to attain autonomous decision-making. To accommodate the resource constraints of satellite platforms, the proposed method adopts a lightweight, non-deep learning framework integrated with a few-shot learning strategy. Moreover, onboard processing on satellites could be faced with sensor failure and scan pattern errors, which result in degraded image quality with bad/misaligned pixels and mixed noise. To address these challenges, we develop a novel two-stage pixel-wise label propagation scheme that utilizes only intrinsic spectral features at the single pixel level without the necessity to consider spatial structural information as requested by deep neural networks. In the first stage, initial pixel labels are obtained by propagating selected anchor labels through the constructed anchor-pixel affinity matrix. Subsequently, a top-k pruned sparse graph is generated by directly computing pixel-level similarities. In the second stage, a closed-form solution derived from the sparse graph is employed to replace iterative computations. Furthermore, we developed a rank constraint-based graph clustering algorithm to determine the anchor labels.

In biomedical engineering, artificial intelligence has become a pivotal tool for enhancing medical diagnostics, particularly in medical image classification tasks such as detecting pneumonia from chest X-rays and breast cancer screening. However, real-world medical datasets frequently exhibit severe class imbalance, where positive samples substantially outnumber negative samples, leading to biased models with low recall rates for minority classes. This imbalance not only compromises diagnostic accuracy but also poses clinical misdiagnosis risks. To address this challenge, we propose SDA-QEC (Simplified Diffusion Augmentation with Quantum-Enhanced Classification), an innovative framework that integrates simplified diffusion-based data augmentation with quantum-enhanced feature discrimination. Our approach employs a lightweight diffusion augmentor to generate high-quality synthetic samples for minority classes, rebalancing the training distribution. Subsequently, a quantum feature layer embedded within MobileNetV2 architecture enhances the model's discriminative capability through high-dimensional feature mapping in Hilbert space. Comprehensive experiments on coronary angiography image classification demonstrate that SDA-QEC achieves 98.33% accuracy, 98.78% AUC, and 98.33% F1-score, significantly outperforming classical baselines including ResNet18, MobileNetV2, DenseNet121, and VGG16. Notably, our framework simultaneously attains 98.33% sensitivity and 98.33% specificity, achieving a balanced performance critical for clinical deployment. The proposed method validates the feasibility of integrating generative augmentation with quantum-enhanced modeling in real-world medical imaging tasks, offering a novel research pathway for developing highly reliable medical AI systems in small-sample, highly imbalanced, and high-risk diagnostic scenarios.

Many clinical screening decisions are based on angle measurements. In particular, FemoroAcetabular Impingement (FAI) screening relies on angles traditionally measured on X-rays. However, assessing the height and span of the impingement area requires also a 3D view through an MRI scan. The two modalities inform the surgeon on different aspects of the condition. In this work, we conduct a matched-cohort validation study (89 patients, paired MRI/X-ray) using standard heatmap regression architectures to assess cross-modality clinical equivalence. Seen that landmark detection has been proven effective on X-rays, we show that MRI also achieves equivalent localisation and diagnostic accuracy for cam-type impingement. Our method demonstrates clinical feasibility for FAI assessment in coronal views of 3D MRI volumes, opening the possibility for volumetric analysis through placing further landmarks. These results support integrating automated FAI assessment into routine MRI workflows. Code is released at https://github.com/Malga-Vision/Landmarks-Hip-Conditions

Reliably ensuring Large Language Models (LLMs) follow complex instructions is a critical challenge, as existing benchmarks often fail to reflect real-world use or isolate compliance from task success. We introduce MOSAIC (MOdular Synthetic Assessment of Instruction Compliance), a modular framework that uses a dynamically generated dataset with up to 20 application-oriented generation constraints to enable a granular and independent analysis of this capability. Our evaluation of five LLMs from different families based on this new benchmark demonstrates that compliance is not a monolithic capability but varies significantly with constraint type, quantity, and position. The analysis reveals model-specific weaknesses, uncovers synergistic and conflicting interactions between instructions, and identifies distinct positional biases such as primacy and recency effects. These granular insights are critical for diagnosing model failures and developing more reliable LLMs for systems that demand strict adherence to complex instructions.

LLMs are increasingly embedded in everyday decision-making, yet their outputs can encode subtle, unintended behaviours that shape user beliefs and actions. We refer to these covert, goal-directed behaviours as hidden intentions, which may arise from training and optimisation artefacts, or be deliberately induced by an adversarial developer, yet remain difficult to detect in practice. We introduce a taxonomy of ten categories of hidden intentions, grounded in social science research and organised by intent, mechanism, context, and impact, shifting attention from surface-level behaviours to design-level strategies of influence. We show how hidden intentions can be easily induced in controlled models, providing both testbeds for evaluation and demonstrations of potential misuse. We systematically assess detection methods, including reasoning and non-reasoning LLM judges, and find that detection collapses in realistic open-world settings, particularly under low-prevalence conditions, where false positives overwhelm precision and false negatives conceal true risks. Stress tests on precision-prevalence and precision-FNR trade-offs reveal why auditing fails without vanishingly small false positive rates or strong priors on manipulation types. Finally, a qualitative case study shows that all ten categories manifest in deployed, state-of-the-art LLMs, emphasising the urgent need for robust frameworks. Our work provides the first systematic analysis of detectability failures of hidden intentions in LLMs under open-world settings, offering a foundation for understanding, inducing, and stress-testing such behaviours, and establishing a flexible taxonomy for anticipating evolving threats and informing governance.

To expedite space exploration on Mars, it is indispensable to develop an efficient Martian image compression method for transmitting images through the constrained Mars-to-Earth communication channel. Although the existing learned compression methods have achieved promising results for natural images from earth, there remain two critical issues that hinder their effectiveness for Martian image compression: 1) They overlook the highly-limited computational resources on Mars; 2) They do not utilize the strong \textit{inter-image} similarities across Martian images to advance image compression performance. Motivated by our empirical analysis of the strong \textit{intra-} and \textit{inter-image} similarities from the perspective of texture, color, and semantics, we propose a reference-based Martian asymmetrical image compression (REMAC) approach, which shifts computational complexity from the encoder to the resource-rich decoder and simultaneously improves compression performance. To leverage \textit{inter-image} similarities, we propose a reference-guided entropy module and a ref-decoder that utilize useful information from reference images, reducing redundant operations at the encoder and achieving superior compression performance. To exploit \textit{intra-image} similarities, the ref-decoder adopts a deep, multi-scale architecture with enlarged receptive field size to model long-range spatial dependencies. Additionally, we develop a latent feature recycling mechanism to further alleviate the extreme computational constraints on Mars. Experimental results show that REMAC reduces encoder complexity by 43.51\% compared to the state-of-the-art method, while achieving a BD-PSNR gain of 0.2664 dB.

We present a novel metric for the evaluation of the morphological plausibility of subword segmentation. Unlike the typically used morpheme boundary or retrieval F-score, which requires gold segmentation data that is either unavailable or of inconsistent quality across many languages, our approach utilizes morpho-syntactic features. These are available in resources such as Universal Dependencies or UniMorph for a much wider range of languages. The metric works by probabilistically aligning subwords with morphological features through an IBM Model 1. Our experiments show that the metric correlates well with traditional morpheme boundary recall while being more broadly applicable across languages with different morphological systems.

Reinforcement learning with verifiable rewards (RLVR) succeeds in reasoning tasks (e.g., math and code) by checking the final verifiable answer (i.e., a verifiable dot signal). However, extending this paradigm to open-ended generation is challenging because there is no unambiguous ground truth. Relying on single-dot supervision often leads to inefficiency and reward hacking. To address these issues, we propose reinforcement learning with verifiable reference-based rewards (RLVRR). Instead of checking the final answer, RLVRR extracts an ordered linguistic signal from high-quality references (i.e, reward chain). Specifically, RLVRR decomposes rewards into two dimensions: content, which preserves deterministic core concepts (e.g., keywords), and style, which evaluates adherence to stylistic properties through LLM-based verification. In this way, RLVRR combines the exploratory strength of RL with the efficiency and reliability of supervised fine-tuning (SFT). Extensive experiments on more than 10 benchmarks with Qwen and Llama models confirm the advantages of our approach. RLVRR (1) substantially outperforms SFT trained with ten times more data and advanced reward models, (2) unifies the training of structured reasoning and open-ended generation, and (3) generalizes more effectively while preserving output diversity. These results establish RLVRR as a principled and efficient path toward verifiable reinforcement learning for general-purpose LLM alignment. We release our code and data at https://github.com/YJiangcm/RLVRR.

With context windows of millions of tokens, Long-Context Language Models (LCLMs) can encode entire document collections, offering a strong alternative to conventional retrieval-augmented generation (RAG). However, it remains unclear whether fine-tuning strategies can improve long-context performance and translate to greater robustness under KV-cache compression techniques. In this work, we investigate which training strategies most effectively enhance LCLMs' ability to identify and use relevant information, as well as enhancing their robustness under KV-cache compression. Our experiments show substantial in-domain improvements, achieving gains of up to +20 points over the base model. However, out-of-domain generalization remains task dependent with large variance -- LCLMs excels on finance questions (+9 points), while RAG shows stronger performance on multiple-choice questions (+6 points) over the baseline models. Finally, we show that our fine-tuning approaches bring moderate improvements in robustness under KV-cache compression, with gains varying across tasks.

In multimodal learning, CLIP has been recognized as the \textit{de facto} method for learning a shared latent space across multiple modalities, placing similar representations close to each other and moving them away from dissimilar ones. Although CLIP-based losses effectively align modalities at the semantic level, the resulting latent spaces often remain only partially shared, revealing a structural mismatch known as the modality gap. While the necessity of addressing this phenomenon remains debated, particularly given its limited impact on instance-wise tasks (e.g., retrieval), we prove that its influence is instead strongly pronounced in group-level tasks (e.g., clustering). To support this claim, we introduce a novel method designed to consistently reduce this discrepancy in two-modal settings, with a straightforward extension to the general $n$-modal case. Through our extensive evaluation, we demonstrate our novel insight: while reducing the gap provides only marginal or inconsistent improvements in traditional instance-wise tasks, it significantly enhances group-wise tasks. These findings may reshape our understanding of the modality gap, highlighting its key role in improving performance on tasks requiring semantic grouping.

Accurate prediction of nuclear magnetic resonance (NMR) chemical shifts is fundamental to spectral analysis and molecular structure elucidation, yet existing machine learning methods rely on limited, labor-intensive atom-assigned datasets. We propose a semi-supervised framework that learns NMR chemical shifts from millions of literature-extracted spectra without explicit atom-level assignments, integrating a small amount of labeled data with large-scale unassigned spectra. We formulate chemical shift prediction from literature spectra as a permutation-invariant set supervision problem, and show that under commonly satisfied conditions on the loss function, optimal bipartite matching reduces to a sorting-based loss, enabling stable large-scale semi-supervised training beyond traditional curated datasets. Our models achieve substantially improved accuracy and robustness over state-of-the-art methods and exhibit stronger generalization on significantly larger and more diverse molecular datasets. Moreover, by incorporating solvent information at scale, our approach captures systematic solvent effects across common NMR solvents for the first time. Overall, our results demonstrate that large-scale unlabeled spectra mined from the literature can serve as a practical and effective data source for training NMR shift models, suggesting a broader role of literature-derived, weakly structured data in data-centric AI for science.

Urban bus transit agencies need reliable, network-wide delay predictions to provide accurate arrival information to passengers and support real-time operational control. Accurate predictions help passengers plan their trips, reduce waiting time, and allow operations staff to adjust headways, dispatch extra vehicles, and manage disruptions. Although real-time feeds such as GTFS-Realtime (GTFS-RT) are now widely available, most existing delay prediction systems handle only a few routes, depend on hand-crafted features, and offer little guidance on how to design a scalable, reusable architecture. We present a city-scale prediction pipeline that combines multi-resolution feature engineering, dimensionality reduction, and deep learning. The framework generates 1,683 spatiotemporal features by exploring 23 aggregation combinations over H3 cells, routes, segments, and temporal patterns, and compresses them into 83 components using Adaptive PCA while preserving 95% of the variance. To avoid the "giant cluster" problem that occurs when dense urban areas fall into a single H3 region, we introduce a hybrid H3+topology clustering method that yields 12 balanced route clusters (coefficient of variation 0.608) and enables efficient distributed training. We compare five model architectures on six months of bus operations from the Société de transport de Montréal (STM) network in Montréal. A global LSTM with cluster-aware features achieves the best trade-off between accuracy and efficiency, outperforming transformer models by 18 to 52% while using 275 times fewer parameters. We also report multi-level evaluation at the elementary segment, segment, and trip level with walk-forward validation and latency analysis, showing that the proposed pipeline is suitable for real-time, city-scale deployment and can be reused for other networks with limited adaptation.

Field education is the signature pedagogy of social work, yet providing timely and objective feedback during training is constrained by the availability of instructors and counseling clients. In this paper, we present SWITCH, the Social Work Interactive Training Chatbot. SWITCH integrates realistic client simulation, real-time counseling skill classification, and a Motivational Interviewing (MI) progression system into the training workflow. To model a client, SWITCH uses a cognitively grounded profile comprising static fields (e.g., background, beliefs) and dynamic fields (e.g., emotions, automatic thoughts, openness), allowing the agent's behavior to evolve throughout a session realistically. The skill classification module identifies the counseling skills from the user utterances, and feeds the result to the MI controller that regulates the MI stage transitions. To enhance classification accuracy, we study in-context learning with retrieval over annotated transcripts, and a fine-tuned BERT multi-label classifier. In the experiments, we demonstrated that both BERT-based approach and in-context learning outperforms the baseline with big margin. SWITCH thereby offers a scalable, low-cost, and consistent training workflow that complements field education, and allows supervisors to focus on higher-level mentorship.

Lipschitz-based certification offers efficient, deterministic robustness guarantees but has struggled to scale in model size, training efficiency, and ImageNet performance. We introduce \emph{LipNeXt}, the first \emph{constraint-free} and \emph{convolution-free} 1-Lipschitz architecture for certified robustness. LipNeXt is built using two techniques: (1) a manifold optimization procedure that updates parameters directly on the orthogonal manifold and (2) a \emph{Spatial Shift Module} to model spatial pattern without convolutions. The full network uses orthogonal projections, spatial shifts, a simple 1-Lipschitz $β$-Abs nonlinearity, and $L_2$ spatial pooling to maintain tight Lipschitz control while enabling expressive feature mixing. Across CIFAR-10/100 and Tiny-ImageNet, LipNeXt achieves state-of-the-art clean and certified robust accuracy (CRA), and on ImageNet it scales to 1-2B large models, improving CRA over prior Lipschitz models (e.g., up to $+8\%$ at $\varepsilon{=}1$) while retaining efficient, stable low-precision training. These results demonstrate that Lipschitz-based certification can benefit from modern scaling trends without sacrificing determinism or efficiency.

This study introduces a methodological framework that uses large language models to create virtual personas of real top managers. Drawing on real CEO communications and Moral Foundations Theory, we construct LLM-based participants that simulate the decision-making of individual leaders. Across three phases, we assess construct validity, reliability, and behavioral fidelity by benchmarking these virtual CEOs against human participants. Our results indicate that theoretically scaffolded personas approximate the moral judgements observed in human samples, suggesting that LLM-based personas can serve as credible and complementary tools for organizational research in contexts where direct access to executives is limited. We conclude by outlining implications for future research using LLM-based personas in organizational settings.

Timely interpretation of satellite imagery is critical for disaster response, yet existing vision-language benchmarks for remote sensing largely focus on coarse labels and image-level recognition, overlooking the functional understanding and instruction robustness required in real humanitarian workflows. We introduce DisasterInsight, a multimodal benchmark designed to evaluate vision-language models (VLMs) on realistic disaster analysis tasks. DisasterInsight restructures the xBD dataset into approximately 112K building-centered instances and supports instruction-diverse evaluation across multiple tasks, including building-function classification, damage-level and disaster-type classification, counting, and structured report generation aligned with humanitarian assessment guidelines. To establish domain-adapted baselines, we propose DI-Chat, obtained by fine-tuning existing VLM backbones on disaster-specific instruction data using parameter-efficient Low-Rank Adaptation (LoRA). Extensive experiments on state-of-the-art generic and remote-sensing VLMs reveal substantial performance gaps across tasks, particularly in damage understanding and structured report generation. DI-Chat achieves significant improvements on damage-level and disaster-type classification as well as report generation quality, while building-function classification remains challenging for all evaluated models. DisasterInsight provides a unified benchmark for studying grounded multimodal reasoning in disaster imagery.

Vision-and-Language Navigation (VLN) requires an embodied agent to navigate in a complex 3D environment according to natural language instructions. Recent progress in large language models (LLMs) has enabled language-driven navigation with improved interpretability. However, most LLM-based agents still rely on single-shot action decisions, where the model must choose one option from noisy, textualized multi-perspective observations. Due to local mismatches and imperfect intermediate reasoning, such decisions can easily deviate from the correct path, leading to error accumulation and reduced reliability in unseen environments. In this paper, we propose DV-VLN, a new VLN framework that follows a generate-then-verify paradigm. DV-VLN first performs parameter-efficient in-domain adaptation of an open-source LLaMA-2 backbone to produce a structured navigational chain-of-thought, and then verifies candidate actions with two complementary channels: True-False Verification (TFV) and Masked-Entity Verification (MEV). DV-VLN selects actions by aggregating verification successes across multiple samples, yielding interpretable scores for reranking. Experiments on R2R, RxR (English subset), and REVERIE show that DV-VLN consistently improves over direct prediction and sampling-only baselines, achieving competitive performance among language-only VLN agents and promising results compared with several cross-modal systems.Code is available at https://github.com/PlumJun/DV-VLN.

Large Language Models (LLMs) offer strong generative capabilities, but many applications require explicit and \textit{fine-grained} control over specific textual concepts, such as humor, persuasiveness, or formality. Prior approaches in prompting and representation engineering can provide coarse or single-attribute control, but systematic evaluation of multi-attribute settings remains limited. We introduce an evaluation framework for fine-grained controllability for both single- and dual-concept scenarios, focusing on linguistically distinct concept pairs (e.g., persuasiveness vs.~humor). Surprisingly, across multiple LLMs and generative tasks, we find that performance often drops in the dual-concept setting, even though the chosen concepts should in principle be separable. This reveals a fundamental limitation of naive prompting-based control: models struggle with compositionality even when concepts are intuitively independent. Our framework provides systematic evidence of this gap and offers a principled approach for measuring the ability of future methods for multi-concept control.

Deep reinforcement learning has proven to be a powerful approach to solving control tasks, but its characteristic high-frequency oscillations make it difficult to apply in real-world environments. While prior methods have addressed action oscillations via architectural or loss-based methods, the latter typically depend on heuristic or synthetic definitions of state similarity to promote action consistency, which often fail to accurately reflect the underlying system dynamics. In this paper, we propose a novel loss-based method by introducing a transition-induced similar state. The transition-induced similar state is defined as the distribution of next states transitioned from the previous state. Since it utilizes only environmental feedback and actually collected data, it better captures system dynamics. Building upon this foundation, we introduce Action Smoothing by Aligning Actions with Predictions from Preceding States (ASAP), an action smoothing method that effectively mitigates action oscillations. ASAP enforces action smoothness by aligning the actions with those taken in transition-induced similar states and by penalizing second-order differences to suppress high-frequency oscillations. Experiments in Gymnasium and Isaac-Lab environments demonstrate that ASAP yields smoother control and improved policy performance over existing methods.

Large language models store biomedical facts with uneven strength after pretraining: some facts are present in the weights but are not reliably accessible under deterministic decoding (latent knowledge), while others are scarcely represented. We fine tuned Llama 3.1 8B Instruct to learn ontology term identifier mappings from the Human Phenotype Ontology (800 pairs) and the Gene Ontology (400 training pairs), withholding 400 GO pairs to test generalization. Treating learning as a time to event process across 20 epochs, we used stochastic decoding to detect latent knowledge at baseline and Cox proportional hazards models to identify predictors of acquisition, generalization, and degradation. Baseline deterministic recall for HPO was 2.8%, rising to 71.9% after fine-tuning. Latent knowledge was the strongest predictor of faster fact acquisition (HR 2.6) and was associated with earlier, higher peak learning rates and faster convergence; identifier frequency and curated annotation counts had smaller effects. Generalization to withheld GO facts was uncommon (5.8%) but more likely when latent knowledge was present. Previously correct GO mappings degraded more often for withheld (unseen) terms than for trained (seen) terms, suggesting a protective effect of reinforcement during training. These results show that latent knowledge predicts both the speed of factual learning during fine-tuning and the limited generalization of unseen ontology facts, while resistance to degradation depends on whether facts are reinforced.

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or loosely linked examinations, introducing subjectivity and fragmented care. Limited access to high-quality imaging tools and specialist expertise further compromises consistency and equity in real-world use. To address these gaps, we developed Fair-Eye Net, a fair, reliable multimodal AI system closing the clinical loop from glaucoma screening to follow-up and risk alerting. It integrates fundus photos, OCT structural metrics, VF functional indices, and demographic factors via a dual-stream heterogeneous fusion architecture, with an uncertainty-aware hierarchical gating strategy for selective prediction and safe referral. A fairness constraint reduces missed diagnoses in disadvantaged subgroups. Experimental results show it achieved an AUC of 0.912 (96.7% specificity), cut racial false-negativity disparity by 73.4% (12.31% to 3.28%), maintained stable cross-domain performance, and enabled 3-12 months of early risk alerts (92% sensitivity, 88% specificity). Unlike post hoc fairness adjustments, Fair-Eye Net optimizes fairness as a primary goal with clinical reliability via multitask learning, offering a reproducible path for clinical translation and large-scale deployment to advance global eye health equity.

Real-world audio recordings often contain multiple speakers and various degradations, which limit both the quantity and quality of speech data available for building state-of-the-art speech processing models. Although end-to-end approaches that concatenate speech enhancement (SE) and speech separation (SS) to obtain a clean speech signal for each speaker are promising, conventional SE-SS methods suffer from complex degradations beyond additive noise. To this end, we propose \textbf{Geneses}, a generative framework to achieve unified, high-quality SE--SS. Our Geneses leverages latent flow matching to estimate each speaker's clean speech features using multi-modal diffusion Transformer conditioned on self-supervised learning representation from noisy mixture. We conduct experimental evaluation using two-speaker mixtures from LibriTTS-R under two conditions: additive-noise-only and complex degradations. The results demonstrate that Geneses significantly outperforms a conventional mask-based SE--SS method across various objective metrics with high robustness against complex degradations. Audio samples are available in our demo page.

Generating holistic co-speech gestures that integrate full-body motion with facial expressions suffers from semantically incoherent coordination on body motion and spatially unstable meaningless movements due to existing part-decomposed or frame-level regression methods, We introduce 3DGesPolicy, a novel action-based framework that reformulates holistic gesture generation as a continuous trajectory control problem through diffusion policy from robotics. By modeling frame-to-frame variations as unified holistic actions, our method effectively learns inter-frame holistic gesture motion patterns and ensures both spatially and semantically coherent movement trajectories that adhere to realistic motion manifolds. To further bridge the gap in expressive alignment, we propose a Gesture-Audio-Phoneme (GAP) fusion module that can deeply integrate and refine multi-modal signals, ensuring structured and fine-grained alignment between speech semantics, body motion, and facial expressions. Extensive quantitative and qualitative experiments on the BEAT2 dataset demonstrate the effectiveness of our 3DGesPolicy across other state-of-the-art methods in generating natural, expressive, and highly speech-aligned holistic gestures.

Geometric morphometrics (GMM) is widely used to quantify shape variation, more recently serving as input for machine learning (ML) analyses. Standard practice aligns all specimens via Generalized Procrustes Analysis (GPA) prior to splitting data into training and test sets, potentially introducing statistical dependence and contaminating downstream predictive models. Here, the effects of GPA-induced contamination are formally characterised using controlled 2D and 3D simulations across varying sample sizes, landmark densities, and allometric patterns. A novel realignment procedure is proposed, whereby test specimens are aligned to the training set prior to model fitting, eliminating cross-sample dependency. Simulations reveal a robust "diagonal" in sample-size vs. landmark-space, reflecting the scaling of RMSE under isotropic variation, with slopes analytically derived from the degrees of freedom in Procrustes tangent space. The importance of spatial autocorrelation among landmarks is further demonstrated using linear and convolutional regression models, highlighting performance degradation when landmark relationships are ignored. This work establishes the need for careful preprocessing in ML applications of GMM, provides practical guidelines for realignment, and clarifies fundamental statistical constraints inherent to Procrustes shape space.

Deep graph learning models have demonstrated remarkable capabilities in processing graph-structured data and have been widely applied across various fields. However, their complex internal architectures and lack of transparency make it difficult to explain their decisions, resulting in opaque models that users find hard to understand and trust. In this paper, we explore model-level explanation techniques for deep graph learning models, aiming to provide users with a comprehensive understanding of the models' overall decision-making processes and underlying mechanisms. Specifically, we address the problem of counterfactual explanations for deep graph learning models by introducing a generative model-level counterfactual explanation approach called GCFX, which is based on deep graph generation. This approach generates a set of high-quality counterfactual explanations that reflect the model's global predictive behavior by leveraging an enhanced deep graph generation framework and a global summarization algorithm. GCFX features an architecture that combines dual encoders, structure-aware taggers, and Message Passing Neural Network decoders, enabling it to accurately learn the true latent distribution of input data and generate high-quality, closely related counterfactual examples. Subsequently, a global counterfactual summarization algorithm selects the most representative and comprehensive explanations from numerous candidate counterfactuals, providing broad insights into the model's global predictive patterns. Experiments on a synthetic dataset and several real-world datasets demonstrate that GCFX outperforms existing methods in terms of counterfactual validity and coverage while maintaining low explanation costs, thereby offering crucial support for enhancing the practicality and trustworthiness of global counterfactual explanations.